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Found 256 clinical trials
Supporting Treatment Outcomes Among PWID (STOP-C)

The goal of this study is to improve HCV care continuum outcomes for people who inject drugs (PWID), reduce potential onward transmission to others and improve HIV outcomes among those who are HIV/HCV coinfected. The study will evaluate whether HCV treatment outcomes (sustained virologic response, treatment completion, adherence) and post …

atazanavir
HIV Vaccine
  • 0 views
  • 23 May, 2022
  • 1 location
A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women

To achieve an AIDS-free generation, there is a critical need for programs which go beyond individual-level behavior change to reduce HIV and STI infections among adolescent girls and young women in sub-Saharan Africa. Informed, Motivated, Aware, and Responsible Adolescents and Adults (IMARA) is an evidence-based HIV-prevention intervention for adolescent girls …

HIV Vaccine
Accepts healthy volunteers
hiv test
pre-exposure prophylaxis (prep)
AIDS
  • 0 views
  • 23 Nov, 2021
  • 1 location
Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among Justice-involved Populations (ACTION)

This is a 5-year Hybrid Type 1 Effectiveness-Implementation Randomized Control Trial (RCT) that compares two models of linking and retaining individuals recently released from custody to the continuum of community-based HIV and opioid use disorder (OUD) prevention and treatment, medication for opioid use disorder (MOUD) service cascades of care.

stimulant
opioid use
opioid
injection drug
  • 17 views
  • 27 Apr, 2022
  • 2 locations
Isisekelo Sempilo Trial to Optimize Peer (Thetha Nami) Delivery of HIV Prevention to Young People in Rural KwaZulu-Natal

Despite advances in efficacious, efficient and safe biomedical tools to reduce HIV transmission and acquisition the HIV epidemic in South Africa(SA) remains an intractable problem, with the lifetime risk of infection approaching 70% for a 15-year-old girl currently living in northern KwaZulu-Natal, the Africa Health Research Institute(AHRI) research setting. This …

Accepts healthy volunteers
  • 0 views
  • 10 Mar, 2022
  • 1 location
Improve Treatment Outcomes for Tuberculosis Infection in Tertiary Care Hospitals

Early diagnosis can contribute to good treatment outcomes and isolate infection control.

  • 4 views
  • 11 Apr, 2022
  • 4 locations
IMPACt of an Enhanced Screening Program on the Detection of Non-AIDS NEOplasms in HIV Patients

Introduction: The incidence of malignancies is higher in the HIV-infected population than in the general population, and it is already one of the leading causes of death in people living with the virus. It is estimated that the situation will be aggravated by the progressive aging of the HIV-infected population. …

  • 0 views
  • 15 Feb, 2021
  • 1 location
Reaching 90 90 90 in Adolescents in Zambia: Using All Our SKILLZ (SKILLZ)

"SKILLZ," is a mixed methods evaluation of the Grassroots Soccer (GRS) SKILLZ Package based in Lusaka, Zambia. The package is made up of three football-based programs: (1) SKILLZ-Girl - implemented in schools as part of a 10-week program culminating in a tournament event; (2) SKILLZ-Club - implemented as an ongoing …

hiv test
Accepts healthy volunteers
AIDS
HIV Vaccine
  • 0 views
  • 11 Jul, 2022
  • 1 location
Expedited Partner Therapy and the HIV Prevention Cascade (EPT and MSM)

The HIV epidemic in Peru remains concentrated in the subpopulation of men who have sex with men (MSM), where the prevalence of disease has been estimated between 10-22% in recent epidemiologic surveys. Partner-based methods to limit the spread of HIV and STI co-infection, including partner notification and partner treatment, provide …

  • 0 views
  • 03 Jun, 2022
  • 1 location
Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity

This study will address whether cannabis affects antiretroviral therapy (ART) drug concentrations, mood, and thinking. The project will have two phases. Phase 1 is an observational study, in

antiretroviral therapy
Accepts healthy volunteers
dolutegravir
  • 5 views
  • 27 May, 2022
  • 1 location
Rapid Start vs. Standard Start Antiretroviral Therapy (ART) in HIV

This study plans to learn about whether starting HIV treatment very soon after diagnosis is more beneficial than waiting until entering routine clinical care after diagnosis.

  • 0 views
  • 28 Jan, 2021
  • 3 locations