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Found 271 clinical trials
Imaging and Biopsy of HIV-Infected Individuals Undergoing Analytic Treatment Interruption

Background Human immunodeficiency virus (HIV) infects CD4 T cells. There is no cure for HIV. People with HIV need to take daily medications called antiretroviral

  • 02 Jul, 2022
  • 1 location
Probiotic Supplementation for Those Immune Non-responders With HIV-1 Infection

Gut bacterial community diversity and composition, immune recovery and activation in peripheral plasma/mucosa, plasma levels of gut damage, microbial translocation and inflammation at baseline and after 6 months of receiving intervention will be analyzed.

  • 25 Apr, 2022
  • 1 location
Artificial Intelligence to Measure Adherence to Oral Medication

The aims of this project is to use an artificial intelligence (AI) smartphone app to provide support for medication adherence by patients with first episode psychosis.

  • 25 Mar, 2022
  • 2 locations
Unobtrusive Sensing of Medication Intake ("USE-MI") (USE-MI)

The purpose of this study is to test the USE-MI system hardware and software to see if it can accurately measure when subjects take their HIV-related medications and help them remember to take these medications. With the use of a smartwatch and smartphone "app", investigators hope to be able to …

  • 16 May, 2022
  • 1 location
The Effectiveness of High Resolution Microendoscopy for People Living With HIV

The investigators have developed a portable, battery-operated, mobile high-resolution microendoscope (mHRME) that provides subcellular images of the anal epithelium, delineating the cellular and morphologic changes associated with neoplasia. The investigators' central hypothesis is that this 'optical' approach will increase the efficiency, clinical impact, and cost-effectiveness of the current standard of …

  • 18 Sep, 2021
  • 1 location
Dolutegravir-Lamivudine for na ve HIV-Infected Patients With 200 CD4/mm3

Protocol Title: DOLCE: Dolutegravir-Lamivudine for nave HIV-Infected Patients with 200 CD4/mm3 Protocol Number: FH-57 Study Objectives: To assess the antiviral activity at week 48 of DTG+3TC among nave HIV patients with a CD4 count 200 cells /mm3.

  • 04 Oct, 2021
  • 4 locations
Intermittent Oral Naltrexone Enhanced With an Ecological Momentary Intervention for Methamphetamine-using MSM

This is a double-blind, placebo-controlled phase 2b trial in which 54 MSM who use meth will be randomly assigned (2:1) to receive 12 weeks of as-needed intermittent oral naltrexone 50 mg enhanced with an EMA-informed EMI platform, or receive as-needed placebo with EMA-informed EMI. The 12-week treatment period is consistent …

Accepts healthy volunteers
  • 10 Apr, 2022
  • 1 location
PrEP Talk: PrEP Uptake With Young Black MSM and Their Close Friends

Young Black MSM (YBMSM) are at critically high and disproportionate HIV risk. Reducing HIV incidence rates among YBMSM will likely require increased adoption of additional strategies such as pre-exposure prophylaxis (PrEP). PrEP is a FDA approved medication for HIV that also prevents HIV transmission when taken appropriately. Interventions are needed …

  • 26 Jan, 2021
  • 1 location
Antiretroviral Therapy for Acute and Chronic HIV Infection (AAHIV)

This is a protocol designed to randomize subjects with acute HIV infection to receive standard HAART or mega-HAART for subject who are enrolled in SEARCH 010 study (protocol title: Establish and characterize an acute HIV infection cohort in a Thai high risk population. To describe the impact of standard HAART …

  • 23 Jan, 2022
  • 1 location
Community-Based Model for Delivery of Antiretroviral Therapy in Cambodia

The community-based ART delivery (CAD) model will build on the existing framework to engage community action, operationalized in the current Global Fund-supported project. Community Action Workers (CAW), who are assigned to ART centers and conduct outreach work, are well-suited to administer CAD scheme. KHANA and the project partners all have …

antiretroviral therapy
HIV Vaccine
coronary heart diseases
  • 11 Sep, 2021
  • 3 locations