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Found 300 clinical trials
Catalysing the Containment of COVID-19

profile. No clinically significant interactions are expected with commonly used antihypertensive agents, antidiabetics drugs, antiretroviral agents, steroids or commonly prescribed analgesics

nitazoxanide
organ failure
interferon
oseltamivir
antihypertensive drugs
  • 42 views
  • 25 Jan, 2021
  • 1 location
Emtricitabine Given Once A Day With Other Anti-HIV Drugs in Children With HIV

The purpose of this study is to see if emtricitabine is safe in children infected with HIV and to determine the best dose.

emtricitabine
anti-hiv drugs
lamivudine
stavudine
lopinavir/ritonavir
  • 151 views
  • 07 Nov, 2020
  • 2 locations
Feasibility and Interest of a HIV Quarterly Preventive Global Care in Men Who Have Sex With Men in Sub-Saharan Africa

The objective of the study is to evaluate the feasibility and interest of a HIV quarterly preventive global care for men who have sex with men (MSM) in sub-Saharan Africa to help reducing HIV incidence in this key population, their female partners, and the general population. This interventional, open label, …

HIV Vaccine
venereal disease
  • 22 views
  • 08 Nov, 2020
  • 4 locations
A Trial of Lopinavir/Ritonavir Dosed According to the Who Pediatric Weight Band Dosing Guidelines

The main purpose of this study is to measure the amount of lopinavir/ritonavir (two anti-HIV medications) in the blood. Results from this study will be compared to the levels of the drugs that have been found in other studies that showed that these medications were safe and effective.

kaletra
HIV Vaccine
lopinavir/ritonavir
lopinavir
ritonavir
  • 340 views
  • 08 Nov, 2020
  • 56 locations
HIV Patients Cohort

The purpose of this study is to improve our knowledge concerning HIV infection, treated or not, in the current conditions of care to optimize it.

  • 1 views
  • 23 Jan, 2021
  • 2 locations
Prevention of Mother-to-child Transmission of HIV-1 Using a Rescue Intervention

The second visit of the Expanded Programme of Immunization when the child is 2 months old (EPI-2) represents a unique opportunity to link the EPI and PMTCT programmes and to introduce preventive and therapeutic rescue interventions in order to: 1) Assess the efficacy of the PMTCT cascade up to 2 …

  • 0 views
  • 23 Jan, 2021
  • 3 locations
HIV Antiretroviral Drugs and Metabolism

Hypothesis 1: Ritonavir-based regimens increase triglycerides and VLDL by both increasing VLDL production and decreasing VLDL clearance. Specific Aim 1A: To quantify the effect of ritonavir on VLDL production and clearance using stable isotope turnover and other clearance methods. Specific Aim 1B: To determine the composition of the triglyceride rich …

atazanavir
efavirenz
lopinavir/ritonavir
lopinavir
ritonavir
  • 6 views
  • 07 Nov, 2020
  • 1 location
Combination Antiretroviral Therapy (cART) for PBC

Placebo Controlled, double-blind randomized controlled trial (RCT) with 12 months Tenofovir Disoproxil and Raltegravir for primary biliary cholangitis (PBC) patients unresponsive to Ursodeoxycholic Acid (UDCA). Placebo patients will be offered 12 months open label therapy at unblinding. All patients will be offered an additional 12 months open label therapy. Observational, …

  • 0 views
  • 27 Dec, 2020
  • 5 locations
Alendronate for Prevention of AntiRetroviral Therapy-associated Bone Loss

Antiretroviral therapy (ART) initiation is associated with a significant loss of bone mineral density (BMD), characterised by increases in bone turnover, which is largely limited to the first 48

  • 10 views
  • 23 Jan, 2021
  • 2 locations
Mycophenolate Mofetil in Antiretroviral Na ve Patients 2 (MAN2 Study)

count in chronically HIV-1 infected patients who are not treated with antiretroviral therapy (ART). The researchers also want to know what the effect is of treatment with MMF on plasma HIV-1

antiretroviral therapy
AIDS
hiv-1 rna measurement
antiretroviral agents
hiv-1 infection
  • 17 views
  • 07 Nov, 2020
  • 5 locations