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Found 74 clinical trials
A Pilot Study of Creatine Monohydrate as an Augmenting Agent for ECT in Persons With Major Depressive Disorder

We propose to determine if augmentation of electroconvulsive therapy (ECT) utilized for the treatment of major depressive disorder (MDD) with daily oral creatine will lead to an accelerated response to treatment, an overall increase in response rate, and will protect against cognitive adverse effects associated with ECT. We propose to …

creatine monohydrate
electroconvulsive therapy
major depressive disorder
depression
  • 0 views
  • 25 Jan, 2021
  • 1 location
DNA Diagnostics for Minimizing Metabolic Side-Effects of Antipsychotics

The purpose of this study is to assess patients treated with the antipsychotics aripiprazole (Abilify®), olanzapine (Zyprexa®), quetiapine (Seroquel®), risperidone (Risperdal®), or

antipsychotics
risperidone
aripiprazole
atypical antipsychotic
quetiapine
  • 202 views
  • 07 Nov, 2020
  • 2 locations
A Study of Antipsychotics in Individuals at Clinical High-risk for Psychosis (the SHARP-2 Study)

The current study will improve knowledge on the effectiveness and safety of the use of antipsychotics at the prodromal phase and on factors influencing the outcome, and will eventually

  • 0 views
  • 26 Jan, 2021
  • 1 location
Phenomics and Genomics of Clozapine Pharmacotherapy

A burgeoning body of research has pointed to increased efficacy of clozapine (CLZ) over other antipsychotics in schizophrenia (SCZ). On the other hand, safety concerns likely cause

  • 8 views
  • 23 Jan, 2021
  • 13 locations
Development of Population Norms of the Computerized Neuropsychological Assessment for Effectiveness of the Antipsychotic Treatment in Schizophrenia

routine evaluation of schizophrenia patients. Pharmaceutical industry initiated numerous large scale, multisite studies on the impact of novel antipsychotics on cognitive deficits in

antipsychotics
cognitive deficits
  • 0 views
  • 07 Nov, 2020
  • 1 location
Long-term Antipsychotic Pediatric Safety Trial

The purpose is to evaluate the long-term pathologic weight changes associated with multi-year risperidone or aripiprazole therapy in 3 - <18-year-old children, who have varying durations of prior antipsychotic drug exposure from the start of study Month 0 (M0). This is critical because children appear to have greater vulnerability to …

  • 64 views
  • 25 Feb, 2021
  • 40 locations
Antipsychotic Medicine and Metabolic Syndrome

The purpose of the study is to determine whether antipsychotic treatment is influence psychiatric patients due to endocrine and metabolic status and a quality of life. The investigators expect, that 30-50% of patients will show pharmacon - gene induced weight gain (> 7% of initial bodyweight) while the rest of …

antipsychotics
  • 4 views
  • 07 Nov, 2020
  • 1 location
National Pregnancy Registry for Atypical Antipsychotics

The purpose of the National Pregnancy Registry for Atypical Antipsychotics is to determine the frequency of birth defects among infants exposed to atypical antipsychotics.

antipsychotics
atypical antipsychotic
typical antipsychotic
  • 352 views
  • 24 Jan, 2021
  • 1 location
Pharmacogenetic Profiling of Antipsychotics-Induced X-Syndrome and Diabetes (PAXD)

antipsychotics may be at a higher risk for developing diabetes and ketoacidosis. The association between these atypical antipsychotics and the onset of diabetes is further strengthened by observations

diabetes
antipsychotics
low density lipoprotein
hypertension
hypertriglyceridemia
  • 3 views
  • 07 Nov, 2020
  • 1 location
Prevalence of the Metabolic Syndrome in SPR Taking Antipsychotics

The purpose of this study is to assess the cross-sectional prevalence of the metabolic syndrome in patients with schizophrenia taking antipsychotics.

schizoaffective disorder
antipsychotics
  • 5 views
  • 07 Nov, 2020
  • 1 location