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Found 128 clinical trials
PREvention of STroke in Intracerebral haemorrhaGE Survivors With Atrial Fibrillation

Atrial fibrillation (AF) is the most common form of irregular heart rhythm. In people with AF, blood clots often form in the heart, which can travel to the brain. Blockage of brain arteries by these clots is a major cause of stroke. This type of stroke is called an ischaemic …

clot
edoxaban
brain imaging
intracerebral hemorrhage
apixaban oral tablet
  • 13 views
  • 25 Feb, 2021
  • 28 locations
ALLiance for sEcondary PREvention After an Episode of Acute Coronary Syndrome (ALLEPRE)

The purpose of the ALLEPRE trial is to compare the benefit offered by a structured, intensive and fully nurse-led intensive secondary prevention intervention programme with that offered by standard of care in a high-risk population of patients admitted to hospital because of an ACS.

unstable angina
myocardial infarction
infarct
secondary prevention
angina pectoris
  • 11 views
  • 25 Jan, 2021
  • 7 locations
SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy

SONOBIRDIE Trial is a randomized, single-blind, sham-controlled study designed for a demonstration of the safety and effectiveness of sonolysis (continual transcranial Doppler (TCD) monitoring) in reduction of risk of stroke or transient ischemic attack (TIA), brain infarctions and cognitive decline using a 2-MHz diagnostic probe with a maximal diagnostic energy …

stenosis
carotid artery stenosis
endarterectomy
angiography
MRI
  • 6 views
  • 26 Jan, 2021
  • 2 locations
Optimal Antiplatelet Therapy Following Left Atrial Appendage Closure

SAFE-LAAC Trial has been designed to gather data on the most optimal strategy of antiplatelet therapy after transcatheter left atrial appendage occlusion with Amplatzer Amulet device

left atrial appendage occlusion
transesophageal echocardiography
left atrial appendage closure
aspirin
antiplatelet agents
  • 19 views
  • 22 Jan, 2021
  • 1 location
Dual Antiplatelet Therapy For Shock Patients With Acute Myocardial Infarction

Multicenter randomized double blind trial comparing intravenous cangrelor and oral ticagrelor in patients with acute myocardial infarction complicated by initial cardiogenic shock and treated with primary angioplasty.

ticagrelor
myocardial infarction
percutaneous coronary intervention
cold
heart failure
  • 24 views
  • 25 Jan, 2021
  • 29 locations
Comparison of Cilostazol-based Triple Antiplatelet Therapy Versus Dual Antiplatelet Therapy for Outcomes of below-the Knee Endovascular Intervention in Patients With Critical Limb Ischemia (TAP CLI Study)

. Patients will be randomized in a 1:1:1 manner into triple antiplatelet therapy (TAP: aspirin, clopidogrel, cilostazol) group, dual antiplatelet therapy (DAP: aspirin, clopidogrel) A group, or

  • 0 views
  • 22 Jan, 2021
Short-Term Anticoagulation Versus Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure

The objective of the study is to compare short-term (8 weeks) anticoagulation therapy (DOAC) vs. antiplatelet therapy for the prevention of device thrombosis following transcatheter LAAC

clot
thrombosis
edoxaban
left atrial appendage closure
rivaroxaban
  • 10 views
  • 28 Mar, 2021
  • 1 location
Proton Pump Inhibitor Preventing Upper Gastrointestinal Injury In Patients On Dual Antiplatelet Therapy After CABG

The purpose of this study is to compare the efficacy of 12 months and 1 month of pantoprazole treatment to prevent upper gastrointestinal mucosal injury in patients on dual antiplatelet therapy

  • 0 views
  • 23 Jan, 2021
  • 1 location
Statin and Dual Antiplatelet Therapy to Prevent Early Neurological Deterioration in Branch Atheromatous Disease

pathology of BAD is due to atherosclerosis, the investigators postulate that early intensive medical treatment with dual antiplatelet therapy(DAPT) and high-intensity statin may prevent END and recurrent

  • 0 views
  • 11 Apr, 2021
  • 1 location
Anticoagulant Versus Dual Antiplatelet Therapy for Preventing Leaflet Thrombosis and Cerebral Embolization After Transcatheter Aortic Valve Replacement

This trial is to compare the efficacy of NOAC(Novel Oral Anticoagulants) with edoxaban vs. dual antiplatelet therapy (DAPT) for prevention of leaflet thrombosis (documented by cardiac CT imaging

anticoagulants
regurgitation
MRI
stroke
aortic valve replacement
  • 10 views
  • 27 Jan, 2021
  • 6 locations