Found 128 clinical trials
Antiplatelet Therapy in Acute Mild-Moderate Ischemic Stroke
The risk of early recurrence or progression of acute ischemic stroke is very high, even in patients treated with aspirin. The Chance study show that clopidogrel plus aspirin treatment reduced the risk of recurrent stroke in patients with transient ischemic attack (TIA) or minor ischemic stroke (NIHSS 3) within 24 …
- 4 views
- 15 Feb, 2021
- 1 location
Optimal antiPlatelet Therapy for High Bleeding and Ischemic RISK Patients Trial
Current guidelines recommend that patients with ACS undergoing stent implantation might be offered extended DAPT treatment for up to 30 months if necessary. Therefore, we designed a prospective, multicenter, randomized, placebo-controlled trial among ACS patients with high-risk on ischemic and bleeding who received a new generation of DES and received …
- 8 views
- 26 Jan, 2021
- 1 location
Study to Gather Information About the Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following an Acute Heart Attack
The purpose of this study is to try to find the best dose of the new drug BAY 2433334 to give to participants and to look at how well BAY 2433334 works on top of a dual antiplatelet therapy
- 57 views
- 09 Jun, 2021
- 193 locations
Balloon Angioplasty for Symptomatic Intracranial Artery Stenosis
aggressive medical management including dual antiplatelet therapy and strict management of risk factors, 12.2 percent of patients with 70-99 percent stenosis of intracranial artery had stroke or death during
- 0 views
- 28 Jan, 2021
- 23 locations
Second Enhanced Control of Hypertension and Thrombectomy Stroke Study (ENCHANTED2)
ENCHANTED2 is an international, multicenter, prospective, randomised, open, blinded end-point assessed (PROBE) trial, to assess different approaches to manage blood pressure (BP) in acute ischemic stroke (AIS) patients who have undergone mechanical thrombectomy (MT). There are two nested substudies evaluating different approaches to secondary prevention in this high-risk stroke population.
- 0 views
- 25 Jan, 2021
- 1 location
Ticagrelor Antiplatelet Therapy to Reduce Graft Events and Thrombosis
Saphenous vein graft disease remains an unresolved medical problem. Many vein grafts occlude in the first year after bypass surgery, leading to adverse cardiovascular outcomes, including recurrent angina, myocardial infarction, and the need for repeat coronary intervention. While aspirin is the standard antiplatelet treatment after CABG surgery, 10-20% of vein …
- 28 views
- 23 Jan, 2021
- 2 locations
Optical Coherence Tomography-Guided PCI With Single-Antiplatelet Therapy
Rationale: Dual antiplatelet therapy (DAPT), consisting of aspirin and a P2Y12-inhibitor, reduces the risk of stent thrombosis, myocardial infarction and stroke after coronary stent implantation
- 0 views
- 02 Mar, 2021
- 1 location
Platelet REACtivity According to TICagrelor Dose After Transcatheter AorticValve Implantation
during the first months after the procedure. This treatment is not yet well established. Current guidelines recommend dual antiplatelet therapy with Aspirin and Clopidogrel for 3-6 months after TAVI to
- 0 views
- 25 Jan, 2021
- 1 location
Chronic Subdural Hematoma and Aspirin
The aim of this randomized, blinded, placebo controlled clinical study is to compare the peri- and postoperative bleeding and cardiovascular complication rates of patients undergoing burr-hole trepanation for chronic subdural hematoma with and without discontinuation of low-dose aspirin
- 62 views
- 24 Jan, 2021
- 1 location