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Found 50 clinical trials
Combined Antioxidant Therapy Against Myocardial Reperfusion Injury. Phase I Study.

Background: Acute myocardial infarction (AMI) has remained a leading cause of mortality and disability worldwide. Although percutaneous coronary angioplasty (PCA) is the best treatment for these patients, paradoxically this procedure causes reperfusion injury. Considerable efforts aimed to reduce this damage have been made, but the results are disappointing and there …

myocardial infarction
Accepts healthy volunteers
infarct
antioxidant
  • 0 views
  • 21 Mar, 2022
  • 1 location
Antioxidant Supplement Associated With Oral Probiotics in Patients With PCOS in IVF

The aim of the study is to study the effect of an antioxidant food supplement associated with probiotics on the oocyte quality response, oxidative stress and microbiota function in an in vitro fertilization cycle in patients with polycystic ovarian syndrome

  • 4 views
  • 26 Jan, 2021
  • 1 location
Impacts of Mitochondrial-targeted Antioxidant on Peripheral Artery Disease Patients

Title: Impacts of mitochondrial-targeted antioxidant on leg blood flow and skeletal muscle mitochondrial function in peripheral artery disease patients. Peripheral artery disease (PAD) is a common cardiovascular disease, in which narrowed arteries reduce blood flow to the limbs, causing pain, immobility and in some cases amputation or death. PAD patients …

intermittent claudication
diabetes
arteriopathy
treadmill test
peripheral arterial diseases
  • 5 views
  • 01 Jul, 2022
  • 1 location
Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock (CORVICTES-ΥΜ)

This study has been approved as a nested substudy of a multicenter trial (CORVICTES, Clinicaltrials.gov Identifier: NCT03592693). The current, randomized, placebo-controlled study will compare steroids/vitamin C versus placebo/placebo in septic shock, with respect to cerebral autoregulation, biomarkers, and functional outcome. The following hypotheses will be tested: The steroids/vitamin C/thiamine intervention …

thiamine
  • 10 views
  • 22 Mar, 2022
  • 1 location
Effect of Natural Antioxidant Supplement on Sperm DNA Fragmentation

Observational study to see the effect of use of natural Antioxidant supplement on sperm DNA fragmentation. Subjects will take the natural antioxidant for 3 months prior to repeat testing.

  • 292 views
  • 13 Feb, 2022
  • 1 location
Canadian Children Inflammatory Bowel Disease Network (CIDsCANN)

The initial network clinical study will be an inception cohort study in children with new onset IBD (Inflammatory Bowel Disease) rigorously phenotyped and prospectively followed. Focusing on a prospective, inception cohort of Canadian children of widely varied racial origins provides a unique opportunity to explore environmental risk factors early in …

enteropathy
crohn's disease
ulceration
ulcerative colitis
inflammatory bowel disease
  • 73 views
  • 16 Feb, 2021
  • 13 locations
Study of the Association Between Presbycusis With the Incidence of Frailty

6 months, questions and answers, audiometries, study of fragility, analysis of antioxidants in blood, and samples of urine will be measured Total polyphenols and oxidant capacity.

Accepts healthy volunteers
  • 0 views
  • 29 Oct, 2021
  • 1 location
Long Term Effects of Different Dietary Protocols on Determinants of Health in Patients' Lymphocytes (FTIR)

Food choices and eating habits play an important role in the management of common noncommunicable diseases, i.e. diabetes type II, hypertension, metabolic syndrome and others. However, for many popular diets there is yet no consensus on their actual ability to exert health effects and, regardless of some promising results, the …

  • 0 views
  • 28 Jul, 2022
  • 1 location
Nutritional Status in Subacute Stroke Patients Under Rehabilitation

Recently, is becoming more evident a relationship between malnutrition, stroke-related sarcopenia and/or altered systemic oxidative status in patients with subacute stroke . The aim of this study is the evaluation of nutritional status, the presence of stroke-related sarcopenia and systemic oxidative status in patients with subacute stroke outcomes; another aim …

  • 0 views
  • 24 Nov, 2021
  • 1 location
Systemic Nitrosative/Oxidative Stress in Patients With Acute Brain Injury

Acute brain injury due to traumatic brain injury (TBI), intracerebral haemorrhage (ICH), and aneurysmal subarachnoid haemorrhage (SAH) carries a high morbidity and mortality, in part due to the development of secondary brain injury. The mechanisms behind secondary brain injury are incompletely understood, but oxidative/nitrosative stress and disturbances in the metabolism …

traumatic brain injury
acute brain injuries
  • 0 views
  • 24 Oct, 2021
  • 1 location