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Found 88 clinical trials
Vacuolar ATPase and Drug Resistance of High Grade Gliomas (GLIODRUG-V)

role in chemoresistance. In fact, a low extracellular pH can reduce the efficacy of antineoplastic agents since a low pH might affect the structural integrity of drugs and their ability to pass through

  • 03 May, 2022
  • 1 location
Retrospective Study on the Use of Immunotherapy in Patients With MSI-H Metastatic Colorectal Cancer

oral multikinase inhibitor), trifluridine/tipiracil hydrochloride (TAS-102), an antineoplastic nucleoside analogue, and antibodies anti-epidermal growth factor receptor (EGFR) in patients with RAS wild

  • 26 Jan, 2021
  • 1 location
The Potential of HemoScreen for Monitoring Blood Values in Cancer Patients at Home

To keep cancer patients safe, whilst in chemo therapy, patients come into the hospital for multiple blood tests, in order to provide safe antineoplastic treatment and supportive care. Monitoring

primary cancer
neutrophil count
Accepts healthy volunteers
  • 25 Dec, 2021
  • 1 location
A Registry Study on HIV-related Lymphoma

Retrospective und prospective registry on HIV-associated lymphoma. Data on characteristics, type and toxicity of treatment and outcome of patients with HIV-lymphoma will be collected.

  • 22 Mar, 2022
  • 4 locations
Eribulin as a Second-line Treatment in Triple-negative Advanced Breast Cancer (HERMIONE-10)

Multicenter, retrospective and prospective, cohort, observational study evaluating the clinical efficacy and tolerability of Eribulin as second-line treatment in accordance with the indications authorized by AIFA in patients with triple negative advanced breast cancer in a real world setting.

advanced breast cancer
  • 07 Apr, 2022
  • 1 location
Immune Checkpoint Inhibitors Nephrotoxicity

In recent years, immunotherapy has been postulated as one of the most effective strategy in the fight against cancer. The greatest success in this field has been achieved through the inhibition of molecules involved in the brake of the adaptive immune response. The compounds capable of blocking the action of …

  • 04 Jun, 2021
  • 2 locations
Long Term Implications of Rare Brain Tumours'

Patients diagnosed with oligodendroglioma with a specific molecular profile represent rare tumour groups (about 10% of adult gliomas) with relatively favourable prognosis (median survival between 8 and 12 years). These patients are often treated with surgery, chemotherapy and/or radiotherapy. However, as patients live for a long period of time, they …

  • 03 Feb, 2021
  • 2 locations
Metabolic and Bone Changes After Adjuvant Cancer Treatments in Early Non-metastatic Breast Cancer

Breast cancer is the most common cancer type in European women. Patients treated for early non-metastatic breast cancer comprise a growing group of survivors due to early diagnosis and improved treatment. Many of these survivors experience adverse effects such as decreased bone mineral density, derangement of metabolic markers (fat, glucose, …

bone mineral density
type 2 diabetes mellitus
breast cancer
  • 27 Feb, 2022
  • 1 location