Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 87 clinical trials
Arsenic Trioxide in Recurrent and Metastatic Ovarian Cancer and Endometrial Cancer With P53 Mutation

This study is a Single-center, open, single-arm and non-randomized clinical trial in China. The aim of this study is to evaluate the efficacy, safety, and tolerability of Arsenic trioxide for injection in patients with recurrent and metastatic ovarian cancer and endometrial cancer with P53 mutation A group of 20 women …

cancer of the ovary
ovarian cancer
cancer
solid tumour
metastasis
  • 1 views
  • 25 Jan, 2021
  • 1 location
Anlotinib Plus Toripalimab as First-line Treatment for Advanced Gastric or Gastro-esophageal Junction Cancer (APICAL-GE)

This study is designed to evaluate the efficacy and safety of the combination of Anlotinib wiht Toripalimab in advanced gastric or gastro-oesophageal junction cancer as first-line treatment.

metastasis
liver metastasis
measurable disease
adjuvant chemotherapy
immunostimulants
  • 0 views
  • 27 Feb, 2022
  • 1 location
Oral Gallium Maltolate for the Treatment of Relapsed and Refractory Glioblastoma

This is a phase 1 investigational study to assess the safety and preliminary efficacy of oral gallium maltolate (GaM) in participants with relapsed glioblastoma (GBM).

neutrophil count
platelet count
measurable disease
temozolomide
MRI
  • 0 views
  • 15 Jun, 2022
  • 1 location
Rose Geranium in Sesame Oil Nasal Spray for the Improvement of Nasal Vestibulitis Symptoms in Cancer Patients Receiving Chemotherapy

This phase III trial compares rose geranium in sesame oil nasal spray to isotonic nasal saline in improving symptoms of nasal vestibulitis in cancer patients receiving chemotherapy. Nasal (nose) symptoms (dryness, discomfort, bleeding, scabbing or sores) due to inflammation, termed nasal vestibulitis, is reported as a side effect of cancer-directed …

cancer
antineoplastic
  • 4 views
  • 25 Mar, 2022
  • 20 locations
A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors

This phase II trial studies how well Pemigatinib (an orally administered inhibitor of fibroblast growth factor receptors 1, 2, and 3) works in non-muscle invasive bladder cancer (NMIBC) patients with recurrent tumors and a prior history of low- or intermediate-risk NMIBC tumors. Participants will receive pemigatinib for 4-6 weeks prior …

bladder cancer
neutrophil count
bladder tumor
cancer
white blood cell count
  • 48 views
  • 19 Feb, 2022
  • 1 location
Donafenib Monotherapy for Previously Treated Metastatic Nasopharyngeal Carcinoma

The investigators do the clinical trial (patients with metastatic nasopharyngeal carcinoma treated with donafenib after failure of standard therapy) to assess safety and efficacy of donafenib in patients with metastatic nasopharyngeal carcinoma, progressing after all approved standard therapies.

renal function test
fluoropyrimidine
nasopharyngeal carcinoma
renal function
carcinoma
  • 1 views
  • 26 Jan, 2022
  • 1 location
Radiotherapy for Locally Advanced Pancreatic Carcinomas (Phase II Trial) (LAPC)

This is an interventional, single-arm, open-label study with high dose short course radiotherapy for patients with locally advanced pancreatic cancer.

metastasis
celiac
cancer chemotherapy
  • 0 views
  • 25 Apr, 2022
  • 1 location
ADT +/- Darolutamide in de Novo Metastatic Prostate Cancer Patients With Vulnerable Functional Ability (PEACE6-Vulnerable)

This is a Phase III, international, multicentre, randomised, double-blinded placebo controlled trial, evaluating the efficacy and safety of ADT +/- darolutamide in castration-naïve de novo metastatic prostate cancer patients with vulnerable functional ability who have not elected for docetaxel or other androgen receptor pathway inhibitors.

  • 0 views
  • 16 May, 2022
  • 2 locations
Phase I/II Trial of CPX-351 + Palbociclib in Patients With Acute Myeloid Leukemia

The purpose of this study is to evaluate the safety and tolerability of Palbociclib in combination with investigational (experimental) drug, CPX-351 and evaluate the efficacy of Palbociclib in combination with chemotherapy as measured by overall response rate (ORR), i.e. complete response (CR) and CR with incomplete blood count recovery (CRi) …

chronic myelomonocytic leukemia
daunorubicin
secondary acute myeloid leukemia
ejection fraction
cancer
  • 2 views
  • 13 Jun, 2022
  • 1 location
Efficacy and Safety of Dronabinol in the Improvement of Chemotherapy-induced and Tumor-related Symptoms in Advanced Pancreatic Cancer

Aim of this phase III trial is to investigate the efficacy and safety of dronabinol (orally administered tetrahydrocannabinol (THC)) as adjuvant therapy to first-line standard chemotherapy in patients with metastatic pancreatic cancer for improvement of chemotherapyand tumor-related symptoms applicated by individual titration up to the maximum tolerated dose.

adjuvant therapy
abraxane
gemcitabine
cancer
folfirinox
  • 2 views
  • 21 Mar, 2022
  • 10 locations