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Found 89 clinical trials
Chk2 Inhibitor for Recurrent EpitheliAl periToneal fallopIan or oVarian cancEr (CREATIVE Phase IA Trial)

potential of PHI-101 as a new treatment or concomitant cytotoxic chemotherapeutics for patients with ovarian cancer who are resistant to existing antineoplastic drugs was confirmed.

  • 29 Jan, 2021
  • 1 location
Dabrafenib and Trametinib Combination as a Neoadjuvant Strategy in BRAF-positive Anaplastic Thyroid Cancer

anaplastic thyroid cancer. The prognosis in patients with ATC is poor due to the rapid and invasive tumor growth and the rapid development of metastases. Dabrafenib is an antineoplastic agent, a

  • 16 Feb, 2021
  • 1 location
Cryospray Therapy Versus Standard of Care for Benign Airway Stenosis (CryoStasis)

increase the area of patency. Clinicians may also inject steroids or antineoplastic agents such as mitomycin C. All of these methods have benefits and associated risks. Symptomatic stenosis frequently

  • 22 Apr, 2022
  • 1 location
Anti-PD-1 Antibody in the Treatment of Patients With Malignant Melanoma of the Female Genital Tract

assess efficacy until radiographic progression, initiation of new antineoplastic therapy, withdrawal of consent, or subject lost to follow-up/death. After the end of treatment, an end-of

  • 28 Jan, 2021
  • 1 location
Study Evaluating Neurotoxicity in Patients With Metastatic Gastro Intestinal Cancer Taking Phycocare® or Placebo During Oxaliplatin Based Chemotherapy (PROPERTY)

Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most frequent side effects caused by antineoplastic agents, with a prevalence from 19% to over 85%. Clinically, CIPN is a mostly

  • 12 May, 2022
  • 4 locations
Adjuvant Durvalumab Plus Regorafenib vs Untreated Control in Stage IV Colorectal Cancer Patients With no Evidence of Disease (NED): VIVA Trial (VIVA)

radiofrequency, the erogation of ≥ 60 Gy for stereotactic radiotherapy, complete response to antineoplastic treatments on CT scan. In all these cases CEA and CA 19.9 must be within normal

  • 04 Jun, 2022
  • 1 location
To Assess Efficacy and Safety of Oral Reparixin in Patients With Fatigue and Locally Advanced / Metastatic Breast Cancer

concomitant antineoplastic agents (paclitaxel, or nab-paclitaxel or docetaxel) in adult patients with locally advanced or metastatic breast cancer.

  • 30 May, 2022
  • 6 locations
Fiber to Reduce Colon Cancer in Alaska Native People

-inflammatory and antineoplastic n-3 fish oils, are at increased risk of colon cancer because of colonic butyrate deficiency resulting from their remarkably low consumption of fiber-containing foods. We

Accepts healthy volunteers
cancer screening
colon cancer screening
screening colonoscopy
  • 14 Mar, 2022
  • 2 locations
Immunotherapy In Locally Advanced Rectal Cancer

-mediated anticancer immune response has been widely elucidated. Moreover, antineoplastic agents can be exploited to target other crucial cellular effectors of immunosuppressive tumor microenvironment (i.e

  • 22 Jan, 2021
  • 1 location
Natural Killer Cell (CYNK-001) Infusions in Adults With AML (CYNK001AML01)

This study will find the maximum tolerated dose or the maximum planned dose of CYNK-001 which contains natural killer (NK) cells derived from human placental CD34+ cells and culture-expanded. CYNK-001 cells will be given after lymphodepleting chemotherapy. The safety of this treatment will be evaluated, and researchers want to learn …

secondary acute myeloid leukemia
cancer therapy
treatment regimen
bilateral oophorectomy
  • 27 Jun, 2022
  • 7 locations