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Found 34 clinical trials
Efficacy and Safety of a Single-pill Fixed Combination of Sufficient Losartan/Hydrochlorothiazide in Chinese Hypertensive Patients

Study name: Efficacy and safety of a single-pill fixed combination of sufficient losartan/hydrochlorothiazide in Chinese hypertensive patients (FOCUS) Medicine: Losartan 100 mg/hydrochlorothiazide 25 mg single-pill fixed combination; amlodipine besylate tablet (5 mg/tablet); hydrochlorothiazide tablets (25 mg/tablet) Rationale: Angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) combined with thiazide diuretic …

ace inhibitor
angiotensin
diuretics
hypertension
ambulatory blood pressure monitoring
  • 0 views
  • 06 Feb, 2022
  • 1 location
Study 1: Effect of Minocycline Treatment on Drug-Resistant Hypertensive Patients

Hypertension (HTN) is the single most prevalent risk factor for cardiovascular disease, diabetes, obesity and metabolic syndrome. Recent American Heart Association (AHA) statistics indicate that one-third of all adults in the United States of America suffer from HTN. Despite advances in life style modification and multi-drug therapies, 20-30% of all …

diabetes
cardiovascular disease
systolic blood pressure
metabolic syndrome
diuretics
  • 41 views
  • 08 Jun, 2022
  • 1 location
D-CTAG in the Treatment of Newly Diagnosed Acute Myeloid Leukemia in Elderly Patients

With the aging of society, the incidence of elderly leukemia in China has been increasing year by year. The elderly patients with Acute Leukemia have poor basal state, and there are many important organ diseases such as heart, liver and kidney. The incidence of infection and hemorrhage is high in …

colony stimulating factor
decitabine
filgrastim
granulocyte colony stimulating factor
cytarabine
  • 0 views
  • 18 Feb, 2022
  • 1 location
Effect of Renal Denervation on Stress, Hypertension and Anxiety Management (ERSHAM)

The ERSHAM (Effect of Renal Denervation on Stress, Hypertension and Anxiety Management) is a single-center, interventional, open-label, randomized controlled trial that will be conducted at the Hypertension Unit "ESH Excellence Center'', 1st Cardiology Department of the Medical School of the National and Kapodistrian University of Athens at the General Hospital …

uncontrolled hypertension
angiotensin
antihypertensive therapy
calcium
renin
  • 0 views
  • 04 Oct, 2022
  • 1 location
Efficacy and Safety of EXOSOME-MSC Therapy to Reduce Hyper-inflammation In Moderate COVID-19 Patients (EXOMSC-COV19)

In COVID-19 infection caused by the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is a dysregulation of the immune system response that causes cytokine storm syndrome. SARS-CoV-2 works like a hijacker (hackers), sabotaging communication between cells so that the immune system, like T-cells, kills not only infected cells but …

  • 0 views
  • 26 Mar, 2022
A Pilot Study in Severe Patients With Takayasu Arteritis.

Takayasu arteritis (TAK) is a rare chronic inflammatory arteritis, which lacks an effective well-accepted intervention strategy. We classify TAK patients into 3 levels, including mild, moderate, and severe. And the biological agents tocilizumab and adalimumab are randomly prescribed in severe patients, to find out the relatively better treatment strategy, facilitating …

tocilizumab
adalimumab
  • 0 views
  • 01 Mar, 2022
  • 1 location
Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients

Takayasu arteritis (TAK) is a rare chronic inflammatory arteritis, which lacks an effective well-accepted intervention strategy. Here we tried to classify TAK patients in 3 levels, including mild, moderate, and severe, and prescribe methotrexate and tofacitinib randomly in mild and moderate patients, to observe the relatively better treatment strategy, facilitating …

tofacitinib
methotrexate
  • 4 views
  • 01 Mar, 2022
  • 1 location
The Patients' Disease Management and Self-management Levels

The purpose of this research; The aim of this study is to examine the effects of self-management support given for hypertension patients on patients' adherence to treatment and disease, self-efficacy level, self-care management. This research is a randomized controlled and pretest-posttest applied design. The research will be carried out in …

chronic obstructive pulmonary disease
diabetes
antihypertensive drugs
essential hypertension
hypertension
  • 0 views
  • 03 May, 2022
  • 1 location
Urinary Prostaglandin as a Potential Predictive Marker for Thiazide-induced Hyponatremia: a Prospective Cohort Study (The PROPHECY Study) (PROPHECY)

Thiazides and thiazide-like diuretics are one of the five major classes of antihypertensive drugs. This study is to investigate whether urinary PGE2 concentration at baseline (prior to thiazide

  • 0 views
  • 14 Oct, 2022
  • 1 location
Long-term Cardiovascular Outcomes in Patients With RH and OSA With or Without Treatment With CPAP (SARAH)

control and number of antihypertensive drugs needed is different depending on OSA diagnosis and its treatment; ii) to identify epigenetic profiles and clinical, biological and polygraphic variables with a

sleep apnea
resistant hypertension
antihypertensive drugs
diuretics
hypertension
  • 6 views
  • 27 Jan, 2022
  • 1 location