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Found 35 clinical trials
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Hypertension Intracranial Pulsatility and Brain Amyloid-beta Accumulation in Older Adults (HIPAC Trial)

The aim of this study is to determine if lowering blood pressure using FDA approved medication (antihypertensive drugs) alters brain pulsatility and reduces brain amyloid beta protein

cognitive impairment
dementia
electrocardiogram
calcium
mini-mental state examination
  • 0 views
  • 16 Jun, 2021
  • 1 location
EndovaScular Versus mediCaL mAnagement of Uncomplicated Type B Intramural heMatoma Trial (ESCLAIM)

This trial is a multicenter, open-label and prospective randomized controlled study to compare 1-year outcomes of uncomplicated type B intramural hematoma (IMH) patients undergoing thoracic endovascular aortic repair (TEVAR) plus optimal medical therapy (OMT) with that of those undergoing OMT alone. The primary objective is to test the hypothesis that …

  • 0 views
  • 10 Jun, 2021
  • 1 location
Comparison of Optimal Hypertension Regimens

compare differences in hypertension treatments and ethnicity. The primary objective of this study is to determine if the response to antihypertensive drugs differs by self defined ethnicity.

nephropathy
amlodipine
combinations
stroke
hypertension
  • 601 views
  • 08 Aug, 2021
  • 14 locations
Impact of the Reduction in Antihypertensive Treatment on Total Mortality in Frail Subjects With Low Systolic Blood Pressure: Study in Subjects Over 80 Years Living in Nursing Homes

The investigators hypothesize that a gradual reduction in antihypertensive treatment in nursing home (NH) patients with low systolic blood pressure (SBP) can improve survival through a controlled increase in SBP and a decrease in secondary morbidity due to 'overmedication'. Accordingly, the investigators propose a randomized, case/control trial in NH patients …

hypertension
antihypertensive drugs
systolic blood pressure
  • 10 views
  • 26 Jan, 2021
  • 2 locations
Intensive Management of Blood Pressure and Cholesterol in Elderly Chinese With Hypertension and Atrial Fibrillation

Study name: Intensive management of blood pressure and cholesterol in elderly Chinese with hypertension and atrial fibrillation (IMPRESSION) Medicine: amlodipine/atorvastatin (5/10mg tablet); amlodipine/atorvastatin (5/20mg tablet); allisartan (240mg/tablet). Rationale: controlling blood pressure and cholesterol are both effective means to reduce cardiovascular risks, however, it is still unknown whether high cardiovascular risk …

systolic blood pressure
blood pressure diastolic
amlodipine
fibrillation
cholesterol level
  • 0 views
  • 25 Jan, 2021
  • 1 location
SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy

SONOBIRDIE Trial is a randomized, single-blind, sham-controlled study designed for a demonstration of the safety and effectiveness of sonolysis (continual transcranial Doppler (TCD) monitoring) in reduction of risk of stroke or transient ischemic attack (TIA), brain infarctions and cognitive decline using a 2-MHz diagnostic probe with a maximal diagnostic energy …

angiography
stenosis
carotid artery stenosis
MRI
endarterectomy
  • 6 views
  • 26 Jan, 2021
  • 2 locations
The Effect of Timing of Antihypertensive Medication on Diurnal Fluctuations in Blood Pressure Using a Wearable Sensor With Continuous Monitoring

antihypertensive drugs to balance daytime/nighttime fluctuations in BP to reduce the risk for cardiovascular morbidity and all-cause mortality. To date, the most widely used method for semi-continuous

  • 0 views
  • 08 Apr, 2021
  • 1 location
Early Vascular Adjustments During Hypertensive Pregnancy

Paradoxical fetal and maternal results of studies have led to inconsistent use of antihypertensive drugs or no treatment at all in mild to moderate gestational hypertension in the Netherlands

labetalol
gestational hypertension
antihypertensive therapy
hypertension
diastolic blood pressure
  • 20 views
  • 01 Apr, 2021
  • 1 location
Hypertension Intracranial Pulsatility and Brain Amyloid-beta Accumulation in Older Adults (HIPAC Trial)

The aim of this study is to determine if lowering blood pressure using FDA approved medication (antihypertensive drugs) alters brain pulsatility and reduces brain amyloid beta protein

systolic blood pressure
electrocardiogram
amlodipine
calcium
hypertension
  • 25 views
  • 16 Jun, 2021
  • 1 location
Evaluation of Intestinal Microbiota Manipulation to Treat Resistant Hypertension

) accompanied with increased cardiovascular morbidity and mortality. Hypertensive individuals may present controlled blood pressure (use of up to 03 antihypertensive drugs) or resistant without blood pressure

cardiovascular morbidity
biochemical tests
dysbiosis
glycosylated hemoglobin
obesity
  • 62 views
  • 05 Mar, 2021
  • 1 location