antihistamines Clinical Research Trials

featured

An investigational biologic medication for the treatment of uncontrolled hives despite antihistamine use.

5 Clinic visits over 40 weeks testing a self injected investigational medication versus placebo for the treatment of uncontrolled hives despite antihistamines. You will

29 views
23 Nov, 2020
1 location

featured

A research study for those suffering with chronic hives despite treatment with an antihistamine.

The purpose of this study is to evaluate the safety and effectiveness of an investigational oral medication for the treatment of hives. This study includes 7 clinical visits over approximately 18 weeks.

177 views
26 Sep, 2019
1 location

Antihistamines in Eosinophilic Esophagitis

Researchers are assessing the safety and effectiveness of antihistamines in the treatment of eosinophilic esophagitis.

loratadine

famotidine

eosinophil count

0 views
26 Aug, 2020
1 location

A Safety and Efficacy Study of Ligelizumab in the Treatment of CSU in Japanese Patients Inadequately Controlled With H1- Antihistamines

The purpose of this study is to evaluate the safety and efficacy of ligelizumab in adult Japanese subjects with CSU, who remain symptomatic despite treatment with H1-antihistamines (AHs) at

ligelizumab

a 12

urticaria

antihistamines

4 views
08 Oct, 2020
10 locations

Tranexamic Acid and Spontaneous Chronic Urticaria

that correlates with the severity of symptoms. Patients with UCS resistant to levocetirizine were shown to have higher D-dimer levels than patients who responded to antihistamines. Tranexamic acid is a

levocetirizine

biotherapy

urticaria

antihistamines

omalizumab

0 views
29 Dec, 2019

A Phase I/II Study of Paclitaxel Plus Carboplatin Plus Vorinostat in Recurrent Ovarian Cancer

of each subsequent 21-day treatment cycle. Patients will receive antiemetic therapy according to institutional guidelines as well as premedication with dexamethasone, and antihistamines (an

cancer antigen 125

doxorubicin

paclitaxel

carboplatin

fallopian tube

10 views
07 Nov, 2020
1 location

Cholinergic Urticaria - Efficacy of Dupilumab

The purpose of this study is to assess the efficacy in reducing disease activity and safety of Dupilumab in adult patients with cholinergic urticarial (CholU) who are symptomatic despite H1-antihistamine treatment (licensed dose).

52 views
12 Aug, 2019
2 locations

Open Label Clinical Trial of Intravenous Crotoxin

The primary objective of the study is to assess whether human subjects can be made tolerant to intravenously administered Crotoxin and achieve higher and more therapeutically effective doses levels without the previously reported adverse effects associated with bolus i.m. administration.

investigational treatment

neutrophil count

metastasis

0 views
08 Nov, 2020

EWO1 in Persistent Allergic Rhinitis Patients

The aim of this double-blind, randomized, parallel group, placebo-controlled study is to assess the efficacy and safety of EWO1 in patients with moderate to severe perennial allergic rhinitis (AR).

congestion

allergen

nasal symptoms

rhinitis

nasal congestion

34 views
07 Nov, 2020
1 location

Evaluation of the Safety and Tolerability of TAK-228 With TAK-117 and Paclitaxel in Advanced Solid Tumors

This is an open-label, cohort study to determine the feasibility and tolerability of the combination of TAK-228 and TAK-117 given on days 2-4, 9-11, 16-18, and 23-25 with paclitaxel on days 1, 8, and 15 for one 28-day cycle in patients with advanced solid tumors.

solid tumour