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Found 32 clinical trials
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An investigational biologic medication for the treatment of uncontrolled hives despite antihistamine use.

5 Clinic visits over 40 weeks testing a self injected investigational medication versus placebo for the treatment of uncontrolled hives despite antihistamines. You will

  • 29 views
  • 23 Nov, 2020
  • 1 location
featured
A research study for those suffering with chronic hives despite treatment with an antihistamine.

The purpose of this study is to evaluate the safety and effectiveness of an investigational oral medication for the treatment of hives. This study includes 7 clinical visits over approximately 18 weeks.  

  • 177 views
  • 26 Sep, 2019
  • 1 location
Antihistamines in Eosinophilic Esophagitis

Researchers are assessing the safety and effectiveness of antihistamines in the treatment of eosinophilic esophagitis.

loratadine
famotidine
eosinophil count
  • 0 views
  • 26 Aug, 2020
  • 1 location
A Safety and Efficacy Study of Ligelizumab in the Treatment of CSU in Japanese Patients Inadequately Controlled With H1- Antihistamines

The purpose of this study is to evaluate the safety and efficacy of ligelizumab in adult Japanese subjects with CSU, who remain symptomatic despite treatment with H1-antihistamines (AHs) at

ligelizumab
a 12
urticaria
antihistamines
  • 4 views
  • 08 Oct, 2020
  • 10 locations
Tranexamic Acid and Spontaneous Chronic Urticaria

that correlates with the severity of symptoms. Patients with UCS resistant to levocetirizine were shown to have higher D-dimer levels than patients who responded to antihistamines. Tranexamic acid is a

levocetirizine
biotherapy
urticaria
antihistamines
omalizumab
  • 0 views
  • 29 Dec, 2019
A Phase I/II Study of Paclitaxel Plus Carboplatin Plus Vorinostat in Recurrent Ovarian Cancer

of each subsequent 21-day treatment cycle. Patients will receive antiemetic therapy according to institutional guidelines as well as premedication with dexamethasone, and antihistamines (an

cancer antigen 125
doxorubicin
paclitaxel
carboplatin
fallopian tube
  • 10 views
  • 07 Nov, 2020
  • 1 location
Cholinergic Urticaria - Efficacy of Dupilumab

The purpose of this study is to assess the efficacy in reducing disease activity and safety of Dupilumab in adult patients with cholinergic urticarial (CholU) who are symptomatic despite H1-antihistamine treatment (licensed dose).

  • 52 views
  • 12 Aug, 2019
  • 2 locations
Open Label Clinical Trial of Intravenous Crotoxin

The primary objective of the study is to assess whether human subjects can be made tolerant to intravenously administered Crotoxin and achieve higher and more therapeutically effective doses levels without the previously reported adverse effects associated with bolus i.m. administration.

investigational treatment
neutrophil count
metastasis
  • 0 views
  • 08 Nov, 2020
EWO1 in Persistent Allergic Rhinitis Patients

The aim of this double-blind, randomized, parallel group, placebo-controlled study is to assess the efficacy and safety of EWO1 in patients with moderate to severe perennial allergic rhinitis (AR).

congestion
allergen
nasal symptoms
rhinitis
nasal congestion
  • 34 views
  • 07 Nov, 2020
  • 1 location
Evaluation of the Safety and Tolerability of TAK-228 With TAK-117 and Paclitaxel in Advanced Solid Tumors

This is an open-label, cohort study to determine the feasibility and tolerability of the combination of TAK-228 and TAK-117 given on days 2-4, 9-11, 16-18, and 23-25 with paclitaxel on days 1, 8, and 15 for one 28-day cycle in patients with advanced solid tumors.

solid tumour
paclitaxel
glycosylated hemoglobin
blood transfusion
metastasis
  • 31 views
  • 21 Jun, 2020
  • 1 location