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Found 45 clinical trials
Featured trial
Protective Role of Pre-/ Post-biotics on Gut Inflammation, Dysbiosis, and Life Quality in Rett Syndrome (Biotics_RTT) (Biotics_RTT)

The study will examine the potential efficacy and safety of two pre- and post-biotics on markers for gut inflammation and intestinal microbiota ecology in patients with Rett syndrome. Moreover, this trial will search for possible effects on epileptogenesis and quality of life.

seizure
  • 0 views
  • 11 Jul, 2022
  • 1 location
Featured trial
Double blind, randomized, historical control study of the safety and efficacy of Eslicarbazepine Acetate Monotherapy in subjects with partial epilepsy not well controlled by current antiepileptic drugs

Double blind, randomized, historical control study of the safety and efficacy of Eslicarbazepine Acetate Monotherapy in subjects with partial epilepsy not well controlled by current antiepileptic

  • 736 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Efficacy and Safety of Eslicarbazepine Acetate as adjunctive Therapy for refractory partial seizures in a double blind, randomized, placebo-controlled, parallel-group multicenter clinical trial

Efficacy and Safety of Eslicarbazepine Acetate as adjunctive Therapy for refractory partial seizures in a double blind, randomized, placebo-controlled, parallel-group multicenter clinical trial

  • 62 views
  • 08 Nov, 2020
  • 1 location
Cannabidiol and Focus Study (CBD-Focus) (CBD-Focus)

Cannabidiol (CBD), a non-psychoactive hemp derivative, is an attractive therapeutic target, and is most supported by the scientific community as an antiepileptic, anxiolytic, and antipsychotic

Accepts healthy volunteers
  • 0 views
  • 27 Apr, 2022
  • 1 location
Social Cognition in Pediatric Epilepsy (TOMEPI)

The purpose of this study is to investigate the development of social cognition skills in pediatric epilepsy compared to healthy children. There are evidences indicating that children with epilepsy have executive dysfunctions and language problems. Executive functions refer to multiple cognitive processes that contribute to human higher order abilities, such …

Accepts healthy volunteers
  • 1 views
  • 23 Apr, 2022
  • 1 location
EEG Monitoring for Refractory Status Epilepticus

This is a prospective randomized study to investigate the yield of continuous electroencephalogram (cEEG), as a diagnostic tool in intensive care unit (ICU), for patients with refractory status epilepticus (RSE) and the contribution of this test to the patient final outcome, compared with standard medical care. Specifically, the hypothesis is …

  • 0 views
  • 31 Jul, 2021
  • 1 location
Pharmacokinetic and Placental Transfer of Levetiracetam (EPICEINTE)

Hypotheses: The treatment of epilepsy during pregnancy is difficult because of the risk of anti-epileptic drugs on the one hand and the risk of destabilization of epilepsy in the mother on the other hand. There is limited data on the pharmacokinetics (concentration study) and pharmacodynamics (efficacy and toxicity effects study) …

  • 0 views
  • 12 May, 2022
  • 1 location
Longitudinal Neuroimaging in Sturge-Weber Syndrome

In this project the accuracy of a novel, rapid magnetic resonance imaging (MRI) approach to detect brain abnormalities in patients with Sturge-Weber syndrome (SWS) will be tested; this new imaging approach, that can create multiple types of MR images in about 5 minutes, without contrast administration (and sedation even in …

Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
  • 1 location
In-depth Investigation of Brain Network Interactions (BNI)

Brain stimulation is a means to potentially remediate symptoms in a range of neurological and psychiatric diseases, however, precise targeting of stimulation is necessary to ensure efficacy. The proposed project will use recent advances in functional magnetic resonance imaging to delineate distributed brain networks within individuals, and use these network …

  • 128 views
  • 23 Jul, 2022
  • 1 location
Epilepsy Adherence in Children and Technology (eACT) (eACT)

Fifty-eight percent of children with new-onset epilepsy do not take their antiepileptic drugs (AEDs) as prescribed, which is associated with continued seizures, mortality, poor quality of life

antiepileptics
seizure
  • 78 views
  • 23 Apr, 2022
  • 3 locations