Found 33 clinical trials
Double blind, randomized, historical control study of the safety and efficacy of Eslicarbazepine Acetate Monotherapy in subjects with partial epilepsy not well controlled by current antiepileptic drugs
Double blind, randomized, historical control study of the safety and efficacy of Eslicarbazepine Acetate Monotherapy in subjects with partial epilepsy not well controlled by current antiepileptic
- 736 views
- 08 Nov, 2020
- 1 location
Efficacy and Safety of Eslicarbazepine Acetate as adjunctive Therapy for refractory partial seizures in a double blind, randomized, placebo-controlled, parallel-group multicenter clinical trial
Efficacy and Safety of Eslicarbazepine Acetate as adjunctive Therapy for refractory partial seizures in a double blind, randomized, placebo-controlled, parallel-group multicenter clinical trial
- 62 views
- 08 Nov, 2020
- 1 location
Longitudinal Neuroimaging in Sturge-Weber Syndrome
In this project the accuracy of a novel, rapid magnetic resonance imaging (MRI) approach to detect brain abnormalities in patients with Sturge-Weber syndrome (SWS) will be tested; this new imaging approach, that can create multiple types of MR images in about 5 minutes, without contrast administration (and sedation even in …
- 0 views
- 23 Mar, 2022
- 1 location
In-depth Investigation of Brain Network Interactions (BNI)
Brain stimulation is a means to potentially remediate symptoms in a range of neurological and psychiatric diseases, however, precise targeting of stimulation is necessary to ensure efficacy. The proposed project will use recent advances in functional magnetic resonance imaging to delineate distributed brain networks within individuals, and use these network …
- 128 views
- 04 Oct, 2022
- 1 location
Epilepsy Adherence in Children and Technology (eACT) (eACT)
Fifty-eight percent of children with new-onset epilepsy do not take their antiepileptic drugs (AEDs) as prescribed, which is associated with continued seizures, mortality, poor quality of life
- 78 views
- 23 Apr, 2022
- 3 locations
Generating Evidence on NonEpileptic Stereotypical and Intermittent Symptoms (NESIS) in Chronic Subdural Hematomas
Some patients with chronic subdural hematomas and transient neurological symptoms do not respond to standard antiepileptic drugs. The investigators think that some of them could have cortical
- 0 views
- 07 May, 2021
- 1 location
Treating Hyperexcitability in AD With Levetiracetam (LeAD)
administration of the antiepileptic medication levetiracetam (LEV) normalizes these measures and improves cognition.
- 0 views
- 25 Jan, 2022
- 1 location
Effects of Low-dose Levetiracetam on Clinical Symptoms, Cognition and Hippocampal Hyperactivity in Schizophrenia
Levetiracetam (LEV: (S)-α-ethyl-2-oxo-pyrrolidine acetamide) is an anticonvulsant/antiepileptic drug. The specific aim of this study is to assess the efficacy of low-dose LEV in reducing
- 69 views
- 27 Apr, 2022
- 1 location
STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis (STTEPP)
The investigators propose to conduct a dose-escalation trial of an FDA-approved antiepileptic drug, lacosamide, added to opioid therapy in patients with chronic abdominal pain from chronic
- 0 views
- 12 Aug, 2023
- 4 locations
PREemptive Analgesia With preGABAlin in HEART Surgery
BACKGROUND: Postoperative pain after cardiac surgery has high incidence and is associated with worse morbidity. Pregabalin is a new antiepileptic drug used in patients with chronic pain and has
- 0 views
- 04 Mar, 2021
- 2 locations