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Found 20 clinical trials
Safety and Feasibility Study of Methylene Blue Photodynamic Therapy to Sterilize Deep Tissue Abscess Cavities

The objectives of this Phase 1 study are to evaluate the safety and feasibility of methylene-blue-mediated photodynamic therapy (MB-PDT) performed at the time of abscess drainage to treat deep tissue abscesses. Safety will be evaluated by physical examination and imaging and laboratory studies in order to identify adverse events that …

drainage
cavities
methylene
  • 26 views
  • 05 Apr, 2022
  • 1 location
Oral Akynzeo vs Standard of Care in Preventing CINV in High-risk MEC Patients (MyRisk)

have been identified and an algorithm has been developed to incorporate these factors into the optimal selection of prophylactic antiemetics nausea and/or vomiting

  • 3 views
  • 25 Sep, 2021
  • 5 locations
Triple Therapy for Postoperative Nausea and Vomiting in Laparoscopic Gastrointestinal Surgery

of PONV is very complex, there is an increasing focus on combining antiemetics from different classes for PONV prophylaxis. Fosaprepitant is a neurokinin-1 (NK-1) receptor antagonist to prevent PONV

  • 0 views
  • 26 May, 2022
  • 1 location
RCT of Olanzapine for Control of CIV in Children Receiving HSCT Conditioning

psychiatric illness, does not interact with chemotherapy and is inexpensive. We hypothesize that the addition of olanzapine to standard antiemetics will improve chemotherapy-induced vomiting (CIV) control in

antiemetics
vomiting
granisetron
ondansetron
cancer
  • 2 views
  • 21 Apr, 2022
  • 9 locations
The Effects of Acupuncture and the Therapist´s Communication on Chemotherapy Induced Nausea and Vomiting: a Randomized, Sham-controlled Trial

investigate if chemotherapy-induced emesis, treatment expectancy and quality of life differ between patients who receive A) standard care including antiemetics, B) standard care plus sham acupuncture or C

antiemetics
weak
emetic
acupuncture
immunological adjuvant
  • 47 views
  • 21 Oct, 2022
  • 1 location
Fosaprepitant Combined With Tropisetron Plus Dexamethasone in Preventing Nausea and Emesis During Fractionated Radiotherapy With Weekly Cisplatin Chemotherapy in Cervical Cancer and Nasopharyngeal Cancer

The study is to evaluate the antiemetic effect of adding fosaprepitant to biplet regimen of tropisetron and dexamethasone for patients with cervical cancer or nasopharyngeal cancer treated with radiotherapy and concomitant weekly cisplatin chemotherapy in a south Chinese cohort.

cancer
nasopharyngeal carcinoma
concurrent radiochemotherapy
treatment regimen
carcinoma
  • 0 views
  • 22 Oct, 2022
  • 1 location
BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron

Patients undergoing either an autologous or allogeneic hematopoietic stem cell transplant (HSCT) and receiving preparative chemotherapy experience a considerable amount of chemotherapy-induced nausea and vomiting (CINV). Current strategies at reducing CINV in this patient population are suboptimal due to lack of efficacy and supportive evidence, potential for increased adverse events, …

antiemetics
dexamethasone
preparative regimen
quetiapine
granisetron
  • 1 views
  • 16 Jun, 2022
  • 1 location
The Effects of Inhaled Aromatherapy on Chemotherapy Induced Nausea (CINV) and Vomiting (CINV)

This study is a three group, randomized, double blind, placebo-controlled trial with two repeated measurements. The same measurements will be collected for each participant during two consecutive chemotherapy treatment cycles.Subjects will be provided with written instructions as an educational handout as well as essential oil safety information. Subjects will be …

cancer
ginger extract
nausea
  • 0 views
  • 07 Oct, 2022
  • 1 location
Comparing the Current Hydration Regimen for the ABC02 Chemotherapy Regimen Versus a Shorter Hydration

This is an open label study for any patients with a bile duct cancer or gallbladder cancer, who will be treated with gemcitabine and cisplatin chemotherapy (the ABC02 regime). Patients recruited onto this study will have a reduction of their hydration time and be given Akynzeo as an anti-sickness drug, …

carcinoma
renal function
cholangiocarcinoma
akynzeo
gemcitabine
  • 4 views
  • 04 Oct, 2022
  • 1 location
Alvimopan as a Rescue Treatment of Postoperative Ileus

This study aims to evaluate the cost effectiveness of Alvimopan as rescue therapy in patients undergoing colorectal or small bowel resection who develop POI, and its safety and effectiveness in reducing LOS and POI duration. This will be a prospective randomized control trial with a total of 58 patients, 29 …

bowel resection
rectal disease
flatus
vomiting
postoperative ileus
  • 0 views
  • 07 Oct, 2022
  • 1 location