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Found 24 clinical trials
Featured trial
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of Brexipiprazole as Adjunctive Therapy in the Maintenance of Adults With Major Depressive Disorder

A study to compare the efficacy of brexpiprazole to placebo as adjunctive therapy to antidepressant therapy for the maintenance treatment in adults with major depressive disorder.  

antidepressant therapy
depressive disorder
  • 143 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Double-Blind, Placebo-Controlled Study of Cariprazine as an Adjunct to Antidepressants in the Treatment of Patients With Major Depressive Disorder Who Have Had an Indadequate Response to Antidepressants Alone

A study to evaluate the efficacy, safety, and tolerability of cariprazine compared with placebo as an adjunctive treatment to ongoing antidepressant therapy in patients with major depressive

antidepressant therapy
depressive disorder
antidepressants
  • 120 views
  • 23 Nov, 2020
  • 1 location
Featured trial
An Efficacy and Safety Study of Sirukumab in Participants With Major Depressive Disorder

An Efficacy and Safety Study of Sirukumab in Participants With Major Depressive Disorder

  • 394 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Randomized, Double-blind, Placebo-controlled, Multicenter Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder

A Randomized, Double-blind, Placebo-controlled, Multicenter Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder

  • 540 views
  • 25 Mar, 2021
  • 1 location
Featured trial
An Investigational Medication for Major Depressive Disorder

An Investigational Medication for Major Depressive Disorder

  • 554 views
  • 08 Nov, 2020
  • 1 location
A Phase 2a, Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-1942 Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression

) on a stable course of antidepressant therapy. The dual primary hypotheses of the study are that the daily MK-1942 treatment and/or intermittent MK-1942 treatment are superior to placebo in reducing

  • 76 views
  • 15 Sep, 2022
  • 25 locations
High-definition Transcranial Direct Current Stimulation (HD-tDCS) in Late-life Depression (LLD)

To determine the efficacy of a 2-week daily programme (10 sessions) of HD-tDCS to augment antidepressant therapy in subjects with late-life depression who had residual depressive symptoms

  • 0 views
  • 27 Apr, 2022
  • 1 location
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

depressive disorder with insomnia symptoms (MDDIS) who have had an inadequate response to current antidepressant therapy with a selective serotonin reuptake inhibitor (SSRI) or serotonin-norepinephrine

  • 258 views
  • 10 May, 2022
  • 76 locations
A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

participants with major depressive disorder with insomnia symptoms (MDDIS) who have had an inadequate response to current antidepressant therapy with a selective serotonin reuptake inhibitor (SSRI) or

selective serotonin reuptake inhibitors
vilazodone
citalopram
vortioxetine
antidepressant therapy
  • 1390 views
  • 14 Jul, 2022
  • 123 locations
  • 0 views
  • 18 Sep, 2022
  • 6 locations