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Found 39 clinical trials
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A Phase 2a, Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-1942 Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression

Merck Sharp & Dohme Corp. is conducting this trial to test the investigational drug MK-1942 in people with treatment-resistant depression. The purpose of this trial is to test the safety, efficacy, and tolerability of the trial drug, MK-1942.Additionally, the sponsor is interested to see if subjects who get MK-1942 have …

  • 0 views
  • 06 Apr, 2021
  • 1 location
featured
A Phase 2a, Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-1942 Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression

) on a stable course of antidepressant therapy.The dual primary hypotheses of the study are that the daily MK-1942 treatment and/or intermittent MK-1942 treatment are superior

  • 0 views
  • 23 Mar, 2021
  • 1 location
featured
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of Brexipiprazole as Adjunctive Therapy in the Maintenance of Adults With Major Depressive Disorder

A study to compare the efficacy of brexpiprazole to placebo as adjunctive therapy to antidepressant therapy for the maintenance treatment in adults with major depressive disorder.  

antidepressant therapy
depressive disorder
  • 75 views
  • 23 Nov, 2020
  • 1 location
featured
A Double-Blind, Placebo-Controlled Study of Cariprazine as an Adjunct to Antidepressants in the Treatment of Patients With Major Depressive Disorder Who Have Had an Indadequate Response to Antidepressants Alone

A study to evaluate the efficacy, safety, and tolerability of cariprazine compared with placebo as an adjunctive treatment to ongoing antidepressant therapy in patients with major depressive

antidepressant therapy
antidepressants
depressive disorder
  • 94 views
  • 23 Nov, 2020
  • 1 location
featured
Long-term Safety Study of Rapastinel as Adjunctive Therapy in Patients With Major Depressive Disorder

Long-term Safety Study of Rapastinel as Adjunctive Therapy in Patients With Major Depressive Disorder

  • 264 views
  • 25 Mar, 2021
  • 1 location
featured
An Efficacy and Safety Study of Sirukumab in Participants With Major Depressive Disorder

An Efficacy and Safety Study of Sirukumab in Participants With Major Depressive Disorder

  • 394 views
  • 23 Nov, 2020
  • 1 location
featured
A Randomized, Double-blind, Placebo-controlled, Multicenter Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder

A Randomized, Double-blind, Placebo-controlled, Multicenter Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder

  • 532 views
  • 25 Mar, 2021
  • 1 location
featured
A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-02)

A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-02)

  • 370 views
  • 25 Mar, 2021
  • 1 location
featured
An Investigational Medication for Major Depressive Disorder

An Investigational Medication for Major Depressive Disorder

  • 476 views
  • 08 Nov, 2020
  • 1 location
Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With TRD

adequate antidepressant therapy (ADT). Adequate ADT is defined as a therapeutically sufficient dose for a sufficient treatment period, which would be expected to be effective as listed in the MGH

  • 788 views
  • 25 Jan, 2021
  • 22 locations