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Found 20 clinical trials
CLOSE Versus High Density Mapping Guided Catheter Ablation of Paroxysmal Atrial Fibrillation

The aim of this study is to compare two methods of catheter ablation for treatment of paroxysmal atrial fibrillation (AF). The first method being a modified CLOSE protocol used for the control group and the second high density mapping guided isolation of pulmonary veins used for the interventional group. Comparison …

  • 0 views
  • 09 Mar, 2021
  • 1 location
FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study (LESS-VT)

-refractory monomorphic ventricular tachycardia in whom ventricular tachycardia recurs despite antiarrhythmic drug therapy or when antiarrhythmic drugs are not tolerated or desired.

heart disease
amiodarone
sotalol
antiarrhythmic drug
catheter ablation
  • 40 views
  • 09 Apr, 2022
  • 24 locations
Pragmatic Randomized Clinical Trial of Early Dronedarone Versus Usual Care to Change and Improve Outcomes in Persons With First-Detected Atrial Fibrillation (CHANGE-AFIB)

therapy. The investigators hypothesize that earlier administration of a well-tolerated antiarrhythmic drug proven to reduce hospitalization may result in improved cardiovascular outcomes and quality of

beta blockers
stroke
vascular disease
antiarrhythmic drug
fibrillation
  • 0 views
  • 19 Sep, 2022
  • 19 locations
Safety Assessment for Sotalol Protocol in Outpatient Unit (Sotalol)

Sotalol is an antiarrhythmic medication with proven effects for the suppression and prevention of supraventricular and ventricular arrhythmias. Due to its potential proarrhythmic effect, its introduction should be cautious, and several guidelines recommend starting the medication in hospital settings. However, patients at low risk for a proarrhythmic effect start the …

  • 0 views
  • 25 Jul, 2022
  • 1 location
Refralon in Patients With Recurrence Paroxysmal and Persistent Forms of Atrial Fibrillation Who Underwent Catheter Ablation

It is planned to evaluate the efficacy and safety of the class III antiarrhythmic drug refralon as a drug for pharmacological cardioversion in patients with recurrent atrial fibrillation (AF

radiofrequency ablation
cardioversion
antiarrhythmic drug
arrhythmia
fibrillation
  • 0 views
  • 25 Jul, 2022
  • 1 location
Assessment of Flecainide to Lower the Patent Foramen Ovale Closure Risk of Atrial Fibrillation or Tachycardia (AFLOAT)

assessing the efficacy of any antiarrhythmic drug in the prevention of AF after PFO closure. AFLOAT will be the first randomized study to possibly validate flecainide to prevent AF in these patients.

  • 0 views
  • 18 Sep, 2022
  • 1 location
Using Electrical Nerve Stimulation to Control Atrial Fibrillation (STALL-AF)

The purpose of this study is to examine if sending mild electrical signals just under your skin will improve atrial fibrillation symptoms by controlling your heart rate.

fibrillation
syncope
antiarrhythmic drug
  • 0 views
  • 10 Mar, 2022
Low Voltage-Directed Catheter Ablation for Atrial Fibrillation

A two-pronged approach to evaluate long term success of non-paroxysmal ablation when using a: specified low voltage-directed with pulmonary vein isolation (LD+PVI) approach compared to , an approach of pulmonary vein isolation (PVI) alone.

  • 12 views
  • 21 Apr, 2022
  • 1 location
A Clinical Trial Utilizing Dantrolene in Patients With Ventricular Arrhythmias.

This is a randomized, placebo controlled trial of Dantrolene (N= 84 participants) to demonstrate the feasibility of using I.V. dantrolene to study the effect of RyR2 inhibition on cardiac electrophysiology, hemodynamics and ventricular arrhythmia inducibility in patients with structural heart disease referred for VT ablation. The investigators will also explore …

  • 0 views
  • 15 Nov, 2021
  • 1 location
Refralon Versus Amiodarone for Cardioversion of Paroxysmal Fibrillation and Atrial Flutter

Patients hospitalized with paroxysmal atrial fibrillation and flutter to restore sinus rhythm will be randomized into two groups: one will be cardioversion with refralon and the other with amiodarone

  • 0 views
  • 26 Jul, 2022
  • 1 location