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Found 12 clinical trials
Transgender Estradiol Affirming Therapy

The purpose of this open label, pilot, randomized clinical trial is to evaluate the effectiveness, safety and tolerability of estrogen use in transgender female and the degree of testosterone suppression achieved in this population when placed on gender affirming pharmacological therapy.

  • 0 views
  • 27 Aug, 2021
  • 1 location
Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery

This randomized phase II/III trial studies docetaxel, antiandrogen therapy, and radiation therapy to see how well it works compared with antiandrogen therapy and radiation therapy alone in treating patients with prostate cancer that has been removed by surgery. Androgen can cause the growth of prostate cells. Antihormone therapy may lessen …

  • 1468 views
  • 22 Sep, 2021
  • 329 locations
Neoadjuvant Degarelix With or Without Apalutamide (ARN-509) Followed by Radical Prostatectomy

RATIONALE: Neoadjuvant hormonal therapy using luteinizing hormone releasing hormone (LHRH) agonists and/or anti-androgens has already demonstrated to downstage primary prostate cancer in patients treated by radical prostatectomy without a survival benefit. There is no evidence yet of a survival impact of LHRH antagonist (LHRHa) +/- new-generation anti-androgens in this setting. …

prostatectomy
apalutamide
gonadorelin
platelet count
adenocarcinoma of prostate
  • 0 views
  • 27 Jan, 2021
  • 1 location
Randomized Double-blind Study on the Benefit of Spironolactone for Treating Acne of Adult Woman.

inflammatory lesions and were shown less effective than cycline Antiandrogens, with acetate of cyproterone associated with risks of phlebitis and pulmonary embolism, and increase risk of

isotretinoin
antibiotics
acne treatment
doxycycline
pituitary
  • 1013 views
  • 07 Aug, 2021
  • 9 locations
Topical Cetirizine in Androgenetic Alopecia in Females

Cetirizine is a safe and selective, second-generation histamine H1 receptor antagonist, widely used in daily practice. A study showed that cetirizine causes a significant reduction in both the inflammatory cell infiltrate and PGD2 production. A pilot study on topical cetirizine showed that cetirizine increased total hair density, terminal hair density …

alopecia
androgenic alopecia
topical minoxidil
histamine h1 receptor antagonist
vitamins
  • 441 views
  • 24 Jan, 2021
  • 1 location
Androgen Deprivation Therapy Muscle Protein Metabolism and Blood Glucose

Prostate cancer (PCa) patients receiving androgen deprivation therapy (ADT) (e.g., Zoladex), experience troublesome side effects during and after treatment (e.g., loss of lean body mass (LBM) and increased fat mass). Although the negative effects of ADT on muscle mass are well documented, the cellular effects of ADT on muscle tissue …

insulin
antiandrogen therapy
androgen suppression
zoladex
androgens
  • 45 views
  • 24 May, 2021
  • 1 location
Feasibility and Safety of Physical Exercise in Men With Prostate Cancer

Prostate cancer (PCa) is among the most widespread in the male population and represents 19% of all cancers diagnosed from the age of fifty, in Italy. Androgen deprivation therapy (ADT) and Radiotherapy (RT) are used for increase survival. However, both therapies are associated with significant side effects, such as fatigue, …

  • 0 views
  • 02 Aug, 2021
  • 1 location
Vitamin B6 in Reducing Hot Flashes in Participants With Prostate Cancer Undergoing Antiandrogen Therapy

This pilot phase II trial studies how well vitamin B6 works in reducing hot flashes in participants with prostate cancer undergoing antiandrogen therapy. A nutritional supplement such as vitamin B6 may help improve hot flashes caused by antiandrogen therapy in participants with prostate cancer.

antiandrogens
antiandrogen therapy
cancer
flashes
  • 8 views
  • 29 Jul, 2021
  • 1 location
Antiandrogen Therapy and SBRT in Treating Patients With Recurrent Metastatic Prostate Cancer

This phase II trial studies how well antiandrogen therapy (leuprolide, apalutamide, and abiraterone acetate) and stereotactic body radiation therapy (SBRT) works in treating patients with prostate cancer that has come back and has spread to other parts of the body. Drugs used in chemotherapy, such as leuprolide, apalutamide, and abiraterone …

prostatectomy
antiandrogen therapy
platelet count
abiraterone
antiandrogens
  • 0 views
  • 19 Aug, 2021
  • 1 location
Antiandrogen Therapy Abiraterone Acetate and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer

This phase II trial studies how well antiandrogen therapy, abiraterone acetate, and prednisone with or without neutron radiation therapy work in treating patients with prostate cancer. Hormone therapy such as antiandrogen therapy may fight prostate cancer by blocking the production and interfering with the action of hormones. Abiraterone acetate may …

prostatectomy
antiandrogen therapy
cancer
androgen ablation
ct scan
  • 0 views
  • 22 Sep, 2021
  • 1 location