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Found 10 clinical trials
Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery

This randomized phase II/III trial studies docetaxel, antiandrogen therapy, and radiation therapy to see how well it works compared with antiandrogen therapy and radiation therapy alone in treating patients with prostate cancer that has been removed by surgery. Androgen can cause the growth of prostate cells. Antihormone therapy may lessen …

  • 1468 views
  • 26 Jan, 2021
  • 315 locations
Neoadjuvant Degarelix With or Without Apalutamide (ARN-509) Followed by Radical Prostatectomy

RATIONALE: Neoadjuvant hormonal therapy using luteinizing hormone releasing hormone (LHRH) agonists and/or anti-androgens has already demonstrated to downstage primary prostate cancer in patients treated by radical prostatectomy without a survival benefit. There is no evidence yet of a survival impact of LHRH antagonist (LHRHa) +/- new-generation anti-androgens in this setting. …

adenocarcinoma
antiandrogen therapy
gonadorelin
endocrine therapy
antiandrogens
  • 0 views
  • 26 Jan, 2021
  • 1 location
Randomized Double-blind Study on the Benefit of Spironolactone for Treating Acne of Adult Woman.

inflammatory lesions and were shown less effective than cycline Antiandrogens, with acetate of cyproterone associated with risks of phlebitis and pulmonary embolism, and increase risk of

pituitary
antibiotics
androgens
acne treatment
doxycycline
  • 1013 views
  • 23 Jan, 2021
  • 9 locations
Topical Cetirizine in Androgenetic Alopecia in Females

Cetirizine is a safe and selective, second-generation histamine H1 receptor antagonist, widely used in daily practice. A study showed that cetirizine causes a significant reduction in both the inflammatory cell infiltrate and PGD2 production. A pilot study on topical cetirizine showed that cetirizine increased total hair density, terminal hair density …

androgenic alopecia
alopecia
treatment regimen
histamine h1 receptor antagonist
combinations
  • 437 views
  • 24 Jan, 2021
  • 1 location
Androgen Deprivation Therapy Muscle Protein Metabolism and Blood Glucose

Prostate cancer (PCa) patients receiving androgen deprivation therapy (ADT) (e.g., Zoladex), experience troublesome side effects during and after treatment (e.g., loss of lean body mass (LBM) and increased fat mass). Although the negative effects of ADT on muscle mass are well documented, the cellular effects of ADT on muscle tissue …

androgen suppression
antiandrogen therapy
zoladex
androgens
insulin
  • 45 views
  • 22 Jan, 2021
  • 1 location
Vitamin B6 in Reducing Hot Flashes in Participants With Prostate Cancer Undergoing Antiandrogen Therapy

This pilot phase II trial studies how well vitamin B6 works in reducing hot flashes in participants with prostate cancer undergoing antiandrogen therapy. A nutritional supplement such as vitamin B6 may help improve hot flashes caused by antiandrogen therapy in participants with prostate cancer.

cancer
antiandrogens
antiandrogen therapy
flashes
  • 8 views
  • 25 Jan, 2021
  • 1 location
Antiandrogen Therapy and SBRT in Treating Patients With Recurrent Metastatic Prostate Cancer

This phase II trial studies how well antiandrogen therapy (leuprolide, apalutamide, and abiraterone acetate) and stereotactic body radiation therapy (SBRT) works in treating patients with prostate cancer that has come back and has spread to other parts of the body. Drugs used in chemotherapy, such as leuprolide, apalutamide, and abiraterone …

adenocarcinoma
antiandrogen therapy
antiandrogens
abiraterone
prostate adenocarcinoma
  • 0 views
  • 25 Jan, 2021
Antiandrogen Therapy Abiraterone Acetate and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer

This phase II trial studies how well antiandrogen therapy, abiraterone acetate, and prednisone with or without neutron radiation therapy work in treating patients with prostate cancer. Hormone therapy such as antiandrogen therapy may fight prostate cancer by blocking the production and interfering with the action of hormones. Abiraterone acetate may …

cancer
antiandrogen therapy
androgen suppression
orchiectomy
endocrine therapy
  • 0 views
  • 26 Jan, 2021
  • 1 location
Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

This randomized phase II trial studies how well abiraterone acetate and antiandrogen therapy, with or without cabazitaxel and prednisone, work in treating patients with castration-resistant prostate cancer previously treated with docetaxel that has spread to other parts of the body. Androgens can cause the growth of prostate cancer cells. Hormone …

antiandrogen therapy
androgen suppression
endocrine therapy
orchiectomy
antiandrogens
  • 1518 views
  • 24 Jan, 2021
  • 453 locations
Intramuscular Mechanisms of Androgen Deprivation-related Sarcopenia

Prostate cancer (PCa) is the most common cancer among men and is even more common in the military and veteran population. For patients with advanced prostate cancer, the most common treatment includes lowering the levels of the hormone testosterone as much as possible. This is called "androgen deprivation therapy" or …

antiandrogen therapy
androgen ablation
androgens
gonadotropin
testosterone
  • 0 views
  • 25 Jan, 2021
  • 1 location