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Found 14 clinical trials
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Therapeutic Effect of Cytoreductive Radical Prostatectomy in Men With Newly Diagnosed Metastatic Prostate Cancer

This randomized phase II trial studies how well surgical removal of the prostate and antiandrogen therapy with or without docetaxel work in treating men with newly diagnosed prostate cancer that

  • 22 views
  • 18 Apr, 2021
  • 15 locations
None
Androgen Deprivation Therapy in Treating Patients With Prostate Cancer

RATIONALE: Androgens can cause the growth of prostate cancer cells. Androgen deprivation therapy may stop the adrenal glands from making androgens. PURPOSE: This randomized phase III trial is studying how well androgen deprivation therapy works in treating patients with prostate cancer.

androgen suppression
androgens
antiandrogens
orchiectomy
epinephrine
  • 403 views
  • 07 Nov, 2020
  • 9 locations
None
Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery

This randomized phase II/III trial studies docetaxel, antiandrogen therapy, and radiation therapy to see how well it works compared with antiandrogen therapy and radiation therapy alone in

  • 1468 views
  • 14 Nov, 2021
  • 341 locations
None
Vitamin B6 in Reducing Hot Flashes in Participants With Prostate Cancer Undergoing Antiandrogen Therapy

This pilot phase II trial studies how well vitamin B6 works in reducing hot flashes in participants with prostate cancer undergoing antiandrogen therapy. A nutritional supplement such as vitamin

flashes
cancer
antiandrogens
antiandrogen therapy
  • 8 views
  • 29 Jul, 2021
  • 1 location
None
Antiandrogen Therapy and SBRT in Treating Patients With Recurrent Metastatic Prostate Cancer

This phase II trial studies how well antiandrogen therapy (leuprolide, apalutamide, and abiraterone acetate) and stereotactic body radiation therapy (SBRT) works in treating patients with

antiandrogens
metastasis
prostatectomy
tumor cells
abiraterone
  • 0 views
  • 19 Aug, 2021
  • 1 location
None
Antiandrogen Therapy Abiraterone Acetate and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer

This phase II trial studies how well antiandrogen therapy, abiraterone acetate, and prednisone with or without neutron radiation therapy work in treating patients with prostate cancer. Hormone

androgens
hormone therapy
tumor cells
testosterone
cancer treatment
  • 0 views
  • 01 Oct, 2021
  • 1 location
None
Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

This randomized phase II trial studies how well abiraterone acetate and antiandrogen therapy, with or without cabazitaxel and prednisone, work in treating patients with castration-resistant

androgens
hormone therapy
tumor cells
metastatic prostate cancer
biomarker analysis
  • 1524 views
  • 11 May, 2021
  • 471 locations
None
Feasibility and Safety of Physical Exercise in Men With Prostate Cancer

Prostate cancer (PCa) is among the most widespread in the male population and represents 19% of all cancers diagnosed from the age of fifty, in Italy. Androgen deprivation therapy (ADT) and Radiotherapy (RT) are used for increase survival. However, both therapies are associated with significant side effects, such as fatigue, …

  • 0 views
  • 02 Aug, 2021
  • 1 location
None
Androgen Deprivation Therapy Muscle Protein Metabolism and Blood Glucose

Prostate cancer (PCa) patients receiving androgen deprivation therapy (ADT) (e.g., Zoladex), experience troublesome side effects during and after treatment (e.g., loss of lean body mass (LBM) and increased fat mass). Although the negative effects of ADT on muscle mass are well documented, the cellular effects of ADT on muscle tissue …

androgen suppression
androgens
insulin
zoladex
antiandrogen therapy
  • 45 views
  • 24 May, 2021
  • 1 location
None
Neoadjuvant Degarelix With or Without Apalutamide (ARN-509) Followed by Radical Prostatectomy

RATIONALE: Neoadjuvant hormonal therapy using luteinizing hormone releasing hormone (LHRH) agonists and/or anti-androgens has already demonstrated to downstage primary prostate cancer in patients treated by radical prostatectomy without a survival benefit. There is no evidence yet of a survival impact of LHRH antagonist (LHRHa) +/- new-generation anti-androgens in this setting. …

degarelix
antiandrogens
androgens
prostatectomy
hormone therapy
  • 0 views
  • 27 Jan, 2021
  • 1 location