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Found 10 clinical trials
Therapeutic Effect of Cytoreductive Radical Prostatectomy in Men With Newly Diagnosed Metastatic Prostate Cancer

This randomized phase II trial studies how well surgical removal of the prostate and antiandrogen therapy with or without docetaxel work in treating men with newly diagnosed prostate cancer that

  • 22 views
  • 08 Oct, 2020
  • 15 locations
Androgen Deprivation Therapy in Treating Patients With Prostate Cancer

RATIONALE: Androgens can cause the growth of prostate cancer cells. Androgen deprivation therapy may stop the adrenal glands from making androgens. PURPOSE: This randomized phase III trial is studying how well androgen deprivation therapy works in treating patients with prostate cancer.

androgens
androgen suppression
antiandrogens
epinephrine
orchiectomy
  • 401 views
  • 07 Nov, 2020
  • 9 locations
Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery

This randomized phase II/III trial studies docetaxel, antiandrogen therapy, and radiation therapy to see how well it works compared with antiandrogen therapy and radiation therapy alone in

  • 1468 views
  • 19 Dec, 2020
  • 315 locations
Vitamin B6 in Reducing Hot Flashes in Participants With Prostate Cancer Undergoing Antiandrogen Therapy

This pilot phase II trial studies how well vitamin B6 works in reducing hot flashes in participants with prostate cancer undergoing antiandrogen therapy. A nutritional supplement such as vitamin

antiandrogen therapy
antiandrogens
flashes
cancer
  • 8 views
  • 25 Jan, 2021
  • 1 location
Antiandrogen Therapy and SBRT in Treating Patients With Recurrent Metastatic Prostate Cancer

This phase II trial studies how well antiandrogen therapy (leuprolide, apalutamide, and abiraterone acetate) and stereotactic body radiation therapy (SBRT) works in treating patients with

antiandrogen therapy
antiandrogens
prostate adenocarcinoma
adenocarcinoma
platelet count
  • 0 views
  • 25 Jan, 2021
Antiandrogen Therapy Abiraterone Acetate and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer

This phase II trial studies how well antiandrogen therapy, abiraterone acetate, and prednisone with or without neutron radiation therapy work in treating patients with prostate cancer. Hormone

endocrine therapy
cancer treatment
bone scan
prostatectomy
androgen ablation
  • 0 views
  • 05 Nov, 2020
  • 1 location
Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

This randomized phase II trial studies how well abiraterone acetate and antiandrogen therapy, with or without cabazitaxel and prednisone, work in treating patients with castration-resistant

endocrine therapy
bone scan
cabazitaxel
tumor cells
androgens
  • 1518 views
  • 24 Jan, 2021
  • 453 locations
Androgen Deprivation Therapy Muscle Protein Metabolism and Blood Glucose

Prostate cancer (PCa) patients receiving androgen deprivation therapy (ADT) (e.g., Zoladex), experience troublesome side effects during and after treatment (e.g., loss of lean body mass (LBM) and increased fat mass). Although the negative effects of ADT on muscle mass are well documented, the cellular effects of ADT on muscle tissue …

androgens
antiandrogen therapy
androgen suppression
zoladex
insulin
  • 45 views
  • 22 Jan, 2021
  • 1 location
Neoadjuvant Degarelix With or Without Apalutamide (ARN-509) Followed by Radical Prostatectomy

RATIONALE: Neoadjuvant hormonal therapy using luteinizing hormone releasing hormone (LHRH) agonists and/or anti-androgens has already demonstrated to downstage primary prostate cancer in patients treated by radical prostatectomy without a survival benefit. There is no evidence yet of a survival impact of LHRH antagonist (LHRHa) +/- new-generation anti-androgens in this setting. …

antiandrogens
endocrine therapy
adenocarcinoma
hormone therapy
platelet count
  • 0 views
  • 31 Dec, 2020
  • 1 location
Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer

This phase II trial studies how well surgery and radiation therapy work in treating patients with prostate cancer that has come back or spread to other parts of the body. Radiation therapy uses high energy beams to kill tumor cells and shrink tumors. Surgical procedures, such as oligometastasectomy, may remove …

prostate adenocarcinoma
adenocarcinoma
prostatectomy
positron emission tomography
transrectal ultrasound
  • 0 views
  • 05 Nov, 2020
  • 1 location