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Found 22 clinical trials
Featured trial
  • 278 views
  • 25 Mar, 2021
  • 1 location
None
Examination of Radiographic Progression Efficacy and Safety of Long-Term Treatment With Infliximab in Patients With Ankylosing Spondylitis

Ankylosing spondylitis (AS) is a chronic inflammatory disease that involves the sacroiliac joints, axial skeleton, entheses and peripheral joints. Current therapy for AS is mainly NSAIDs and physiotherapy which are oft insufficient. Treatment with the TNF-alpha blocking agent infliximab was shown to have definite clinical efficacy in patients with active …

NSAID
anti-tumor necrosis factor therapy
steroidal anti-inflammatory drugs
infliximab
tumor necrosis factor alpha
  • 51 views
  • 07 Nov, 2020
  • 8 locations
None
Interest of Continuous Non-Steroidal Anti-Inflammatory Drug Treatment in Ankylosing Spondylitis Patients Treated by Anti-TNF Therapy in the Prevention of Radiographic Outcomes

Ankylosing spondylitis (AS) is a frequent chronic inflammatory rheumatic disease that affects the axial skeleton, starting in the sacroiliac joints and spreading to the spine in most patients. Non-steroidal anti-inflammatory drugs (NSAIDs) are the primary treatment for AS. Even if the use of anti-TNF agents has demonstrated good clinical efficacy …

arthritis
rheumatic diseases
steroidal anti-inflammatory drugs
NSAID
anti-tumor necrosis factor therapy
  • 120 views
  • 05 Feb, 2021
  • 25 locations
None
Study to Demonstrate the Efficacy Safety and Tolerability of Intravenous Secukinumab up to 52 Weeks in Subjects With Active Psoriatic Arthritis

thereafter with 3 mg/kg administered every four weeks) in patients with active psoriatic arthritis (PsA) despite current or previous NSAID, DMARD and/or anti-TNF therapy.

tumor necrosis factor
steroidal anti-inflammatory drugs
retinoids
phototherapy
puva
  • 84 views
  • 16 May, 2021
  • 89 locations
None
De-escalation of Anti-TNF Therapy in Inflammatory Bowel Disease

necrosis factor (anti-TNF) therapy. As a result, 67 to 91% of paediatric patients and 66% of adult patients is still in sustained remission two years after the initiation of anti-TNF therapy. Prolonged use

  • 0 views
  • 27 Mar, 2021
  • 4 locations
None
Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy

daily dietary supplement in pediatric and young adult IBD participants in stable remission receiving infliximab, adalimumab, or infliximab-dyyb biosimilar anti-TNF therapy.

  • 0 views
  • 03 Feb, 2021
  • 2 locations
None
Low Dose Oral Methotrexate in Pediatric Crohn's Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy

The purpose of this study is to determine whether adding low dose methotrexate to anti -TNF therapy is more effective than treatment with anti-TNF therapy alone in inducing and maintaining

  • 91 views
  • 24 Jan, 2021
  • 37 locations
None
The Immunogenicity and Safety of Zostavax in Rheumatoid Arthritis Patients Using Abatacept

patients using anti-TNF therapy is encouraging in that few patients experienced adverse events (56 adverse events in 50 participants, out of 140 participants in total) and that 96.2% of these adverse

varicella
tumor necrosis factor
zoster vaccine
attenuated vaccine
hysterectomy
  • 145 views
  • 20 Aug, 2021
  • 4 locations
None
Adjunctive Treatment With Vitamin D3 in Patients With Active IBD

TNFpathway, suggesting a synergy with anti-TNF therapy. This is a randomized, double blind, placebo-controlled trial to study the effect of Vitamin D3 as an adjunct therapy for patients with active

  • 0 views
  • 08 Mar, 2021
  • 1 location
None
Shingrix Vaccine in Patients With Moderate to Severe Ulcerative Colitis on Tofacitinib

on anti-tumor necrosis alpha (anti-TNF) monotherapy, and superior to those on anti-TNF therapy in combination with a thiopurine. Strong cell mediated immunity is shown to prevent reactivation of HZ

ulcerative colitis
colitis
infliximab
immunosuppressive agents
enteropathy
  • 0 views
  • 28 Jan, 2021
  • 1 location