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Found 59 clinical trials
featured
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy

medicines, for transfusions of red blood cells and platelets, and for collecting blood samples. Preparatory chemotherapy (fludarabine, cyclophosphamide and anti-thymocyte globulin) and total body

myelodysplastic syndromes
myelodysplastic syndrome (mds)
anemia
anemia studies
aplastic anemia
  • 48 views
  • 22 Dec, 2020
  • 1 location
featured
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused with a Reduced Dose of Non-Mobilized Donor T-Cells

of the National Institutes of Health Clinical Center and will receive regular doses of cyclophosphamide, fludarabine, and anti-thymocyte globulin to suppress their immune system and prepare for the

myelodysplastic syndromes
myelodysplastic syndrome (mds)
anemia
anemia studies
aplastic anemia
  • 86 views
  • 22 Dec, 2020
  • 1 location
featured
Antithymocyte Globulin (ATG) and Pegylated Granulocyte Colony Stimulating Factor (GCSF) in New Onset Type 1 Diabetes

Antithymocyte Globulin (ATG) and Pegylated Granulocyte Colony Stimulating Factor (GCSF) in New Onset Type 1 Diabetes

  • 230 views
  • 25 Mar, 2021
  • 1 location
featured
Research Study of ATG and Rituximab in Renal Transplantation (RESTARRT)

Research Study of ATG and Rituximab in Renal Transplantation (RESTARRT)

  • 1078 views
  • 23 Nov, 2020
  • 5 locations
featured
Eltrombopag Added to Standard Immunosuppression in Treatment-Naive Severe Aplastic Anemia

Background: Severe aplastic anemia is a rare and serious blood disorder. It happens when the immune system starts to attack the bone marrow cells. This causes the bone marrow to stop making red blood cells, platelets, and white blood cells. Standard treatment for this disease is horse-ATG and cyclosporine, which …

myelodysplastic syndromes
myelodysplastic syndrome (mds)
anemia
anemia studies
aplastic anemia
  • 123 views
  • 22 Dec, 2020
  • 1 location
Extracorporeal Photopheresis for Medicare Recipients of Lung Allografts

The primary aims of this study is to determine the efficacy and tolerability of Extracorporeal Photopheresis (ECP) for the treatment of either refractory (240) or newly diagnosed (400-450) Bronchiolitis Obliterans Syndrome (BOS) in patients after lung transplantation.In compliance with the Centers for Medicare and Medicaid Services' (CMS) Coverage with Evidence …

  • 5 views
  • 02 May, 2021
  • 22 locations
TLI ATG & Hematopoietic Stem Cell Transplantation and Recipient T Regs Therapy in Living Donor Kidney Transplantation

This study will determine whether a preparatory regimen including total lymphoid irradiation (TLI), anti-thymocyte globulin (ATG) and infusion of the donor hematopoietic stem cells when given

  • 6 views
  • 24 Jan, 2021
  • 2 locations
Allogeneic Transplantation for Pediatric Leukemias With Unrelated Donors

The study proposes the use of Fludarabine, Busulfan, Anti Thymocyte Globulin Rabbit (ATG) and Total Body Irradiation as a preparative regimen before hematopoietic stem cell transplant

fludarabine
busulfan
ejection fraction
remission
antithymocyte globulin
  • 10 views
  • 07 Nov, 2020
  • 1 location
Reduced Toxicity Fludarabine (Flu) + Cyclophosphamide (CPM) + Rabbit Antithymocyte Globulin (rATG) Conditioning Regimen for Unrelated Donor Transplantation in Severe Aplastic Anemia (SAA)

Anti-thymocyte globulin (ATG) has been used in severe aplastic anemia as a part of the conditioning regimen. Among the many kinds of ATG preparations, thymoglobulin had been found to be

fludarabine
cell transplantation
antithymocyte globulin
neutrophil count
cyclophosphamide
  • 26 views
  • 07 Nov, 2020
  • 1 location
Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA)

SSA is a combination of 3 drugs (Cyclosporine [CsA], Eltrombopag [EPAG], and horse anti-thymocyte globulin [h-ATG]). Researchers want to see if starting people at a lower dose of CsA with EPAG before

immunosuppressant
blood disorder
antithymocyte globulin
platelet count
neutrophil count
  • 1 views
  • 27 Feb, 2021
  • 1 location