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Found 31 clinical trials
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Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial

severe PsA. Arm 1 will receive standard step up therapy in the cohort and act as the control group. Arm 2 will receive early combination conventional synthetic disease modifying anti-rheumatic drugs

tumor necrosis factor
tumour necrosis
anti-rheumatic drugs
leflunomide
rheumatic diseases
  • 2 views
  • 05 May, 2021
  • 1 location
None
Vagus Nerve Stimulation for Moderate to Severe Rheumatoid Arthritis

an inadequate response or intolerance to biologic or targeted synthetic Disease-Modifying Anti-Rheumatic Drugs (DMARDs). The study device contains a miniaturized stimulator (implant) that is

DMARD
antirheumatics
  • 0 views
  • 26 Nov, 2021
  • 25 locations
None
Efficacy and Safety of Selective JAK 1 Inhibitor Filgotinib in Active Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate

The administration of Janus kinase (JAK) inhibitors as well as biological disease-modifying anti-rheumatic drugs has dramatically improved even the clinical outcomes in rheumatoid arthritis (RA

antirheumatics
methotrexate
tocilizumab
  • 0 views
  • 10 Nov, 2021
  • 1 location
None
MusculRA: The Effects of Rheumatoid Arthritis on Skeletal Muscle Biomechanics

the patient has had symptoms/disease, not the length of time since RA diagnosis) AND prior to starting biologic Disease-modifying anti-rheumatic drugs (bDMARD) therapy and 15 age-, sex-, and BMI

antirheumatics
rheumatism
rheumatic diseases
DMARD
stiffness
  • 7 views
  • 09 Aug, 2021
  • 2 locations
None
Discontinuation of Methotrexate in Rheumatoid Arthritis Patients Achieving Clinical Remission by Treatment With Upadacitinib Plus Methotrexate

The administration of Janus kinase (JAK) inhibitors as well as biological disease-modifying anti-rheumatic drugs has dramatically improved even the clinical outcomes in rheumatoid arthritis (RA

antirheumatics
methotrexate
remission
rheumatism
  • 0 views
  • 24 Nov, 2021
  • 1 location
None
Arthroscopic Synovectomy of the Wrist in Inflammatory Arthritis

function and reduced quality of life. The first line treatment usually consists of conventional Disease-Modifying Anti-Rheumatic Drugs (cDMARDs) along with bridging therapy using systemic corticosteroids

  • 12 views
  • 07 Mar, 2021
  • 1 location
None
Rheumatoid Arthritis Memory B Cells and Abatacept (RAMBA)

Single-Open Label Study to Assess Changes in the Immune Profile in Response to Treatment with Intravenous Abatacept Adults with Rheumatoid Arthritis who are Naive to Biologic Disease-Modifying Antirheumatic Drugs

antirheumatics
corticosteroids
rheumatism
prednisone
DMARD
  • 14 views
  • 12 Jul, 2021
  • 1 location
None
The MEDIPSA Clinical Trial

The main purpose of this study is to validate the positive effect of "Omnibiotic Stress Repair" on patients with active psoriatic Arthritis.

  • 0 views
  • 28 Mar, 2021
  • 1 location
None
SarS-Cov-2 Viral Infection (COVID-19) in Patients With Chronic Inflammatory Rheumatism

The purpose of this study is to assess whether immunosuppressive therapies used by patients with chronic inflammatory rheumatic diseases have an impact on the viral load and the humoral and cellular responses during viral infection with SarSCoV2, compared to members of their family cluster infected with the same viral strain.

tumor necrosis factor
rheumatism
leflunomide
rheumatic diseases
rituximab
  • 0 views
  • 10 May, 2021
  • 1 location
None
Subunit Vaccine Against Herpes Zoster in RA Patients Treated With JAK-inhibitors (VACCIMIL-ZOSTER)

Background. A new subunit vaccine against herpes zoster (HZ) has recently been approved for vaccination of adults i in Sweden. This vaccine (Shingrix) elicits a strong cellular and humoral immune response in healthy adults regardless of age. Studies on the immunogenicity and efficacy of this vaccine in immunosuppressed patients, such …

prednisolone
DMARD
rheumatic diseases
rheumatism
  • 6 views
  • 24 Jan, 2021
  • 2 locations