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Found 8 clinical trials
Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in PGTC Seizures

This trial is intended to study the safety and effectiveness of an new anti-epileptic drug (AED) on Primary Generalized Tonic-Clonic (PGTC) Seizures. Eligible Subjects will continue to take

  • 0 views
  • 03 Jun, 2022
  • 6 locations
Comparing Pregabalin and Placebo in Patients With Persistent Globus Sensation (Lyrica)

To evaluate the relative merits, safety and effectiveness of pregabalin in globus patients compared with placebo.

  • 0 views
  • 21 Jul, 2022
  • 2 locations
Seizure Treatment in Glioma (STING)

Currently, treatment with a specific anti-epileptic drug mainly depends on the physicians' preference, as there are no studies supporting the use of one specific anticonvulsant in glioma

astrocytoma
anaplastic astrocytoma
levetiracetam
oligodendroglioma
anaplastic oligodendroglioma
  • 9 views
  • 28 Feb, 2022
  • 4 locations
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Lacosamide in Neonates With Repeated Electroencephalographic Neonatal Seizures (LENS)

total minutes of electroencephalographic neonatal seizures (ENS) per hour) in neonates with seizures that are not adequately controlled with previous anti-epileptic drug (AED) treatment.

levetiracetam
anti-epileptic drug
antiepileptics
electroencephalogram
lacosamide
  • 22 views
  • 22 Mar, 2022
  • 24 locations
Uncovering a Novel Therapeutic Target to Reduce Dementia Risk in Parkinson's Disease (TRIP)

The present study is a proof-of-concept clinical trial to test the efficacy of low doses of a repurposed anti-epileptic drug (levetiracetam) in treating memory problems in Parkinson's disease

dementia
cognitive impairment
Accepts healthy volunteers
  • 0 views
  • 25 Jan, 2022
  • 1 location
Role of Zonisamide in Advanced Parkinson's Disease (PD) in Egyptian Population: Pilot Study

Zonisamide (ZNS) (1,2-Benzisoxazole-3-methanesulfonamide) is an anti-epileptic drug. In three double blinded placebo controlled studies, ZNS- as an adjunctive treatment- showed beneficial

levodopa
antiparkinsonian agents
motor symptoms
dyskinesia
  • 0 views
  • 25 Jan, 2022
  • 2 locations
Reducing Hippocampal Hyperactivity and Improving Cognition in Schizophrenia

This study plans to learn more about the effects of levetiracetam (LEV) on brain activity and cognition in schizophrenia and schizoaffective disorder. Levetiracetam is an anti-seizure drug, also called an anticonvulsant.

schizoaffective disorder
Accepts healthy volunteers
  • 68 views
  • 25 Mar, 2022
  • 1 location
Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 in Subjects With Focal Seizures With Temporal Lobe Onset With or Without Secondary Generalization

This is a Phase 2 double-blind, randomized, placebo-controlled study to assess the safety and efficacy of ICV delivery of CT-010 via an implantable pump and a cranial port and dual lumen catheter (CIC) in subjects with focal seizures, with temporal lobe onset with or without secondary generalization. Up to 70 …

electroencephalogram
neurological disorder
central nervous system infection
seizure
psychiatric disorder
  • 0 views
  • 26 Jul, 2021
  • 8 locations