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Found 64 clinical trials
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Pegliposomal Doxorubicin and 5-fluorouracil as Second Line Therapy for Metastatic Gastric Cancer

For second-line chemotherapy for metastatic gastric cancer, single-agent irinotecan is the standard treatment. Anthracyclines are active but lack well designed investigations. The combination of

renal function
solid tumor
neutrophil count
cancer chemotherapy
anthracyclines
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
A Study of RC48-ADC for the Treatment of Locally Advanced or Metastatic Breast Cancer With Low Expression of HER2

This study will compare RC48-ADC to physician choice standard treatment. Participants must have HER2-low breast cancer previous use of anthracyclines, and have been treated with one or two

  • 0 views
  • 14 Mar, 2021
  • 1 location
None
  • 0 views
  • 18 Mar, 2021
  • 1 location
None
Leronlimab (PRO 140) Combined With Carboplatin in Patients With CCR5+ mTNBC

patients with CCR5-positive, locally advanced or metastatic triple-negative breast cancer (mTNBC) who are nave to chemotherapy in metastatic setting but have been exposed to anthracyclines and taxane in

triple negative breast cancer
metastasis
neutrophil count
cancer
carboplatin
  • 36 views
  • 08 Oct, 2021
  • 3 locations
None
Ivabradine to Prevent Anthracycline-induced Cardiotoxicity

Anthracyclines are associated with cardiotoxic effects. Previous studies suggest that enalapril, and or carvedilol, protect against cardiovascular effects of these drugs. Ivabradine

  • 0 views
  • 23 Jan, 2021
  • 1 location
None
Pembrolizumab and Carboplatin in Treating Patients With Circulating Tumor Cells Positive Metastatic Breast Cancer

, HER2 negative metastatic breast cancer previously treated with anthracyclines and taxanes. Previous studies have indicated that recurrent breast cancers are more resistant to chemotherapy and maybe

anticoagulant therapy
triple negative breast cancer
metastasis
immunohistochemistry
cancer
  • 24 views
  • 10 May, 2021
  • 1 location
None
Anthracycline Induced Cardiotoxicity - Early Detection by Combination of Diastolic Strain and T2-mapping

Anthracyclines (e.g. Doxorubicin) are an important and highly effective chemotherapeutic. They are used in various tumor entities and are established for breast cancer treatment. The most

strain
breast cancer, treatment
cancer
cancer treatment
early detection
  • 0 views
  • 23 Jan, 2021
  • 1 location
None
CPX-351+GO in Subjects 55 Years Old or Older With AML

-dose cytarabine, or lenalidomide or a clinical trial drug in combination with hypomethylating agents or low-dose cytarabine, but may not have received intensive AML treatment with anthracyclines and/or

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Remote Ischaemic Preconditioning in Childhood Cancer

focused on changing the formulation or rate of administration of anthracyclines but with no observable benefits. While dexrazoxane, an iron chelator, has shown to reduce cardiotoxic outcomes, there

metastasis
troponin
cancer
childhood cancer
dexrazoxane
  • 0 views
  • 07 May, 2021
  • 2 locations
None
Cancer Adverse Effects PReventIon With Care & Exercise: the CAPRICE Study

Breast cancer is the most common cancer among women worldwide. Similarly, Hodgkin and nonHodgkin lymphomas make up two of the most prevalent cancers in men and women. Even though remarkable improvements in cancer-free survival have been achieved in the last decades, the development of cardiac toxicity, associated with anthracycline-based chemotherapy …

strain
hodgkin's disease
left ventricular dysfunction
troponin
cancer
  • 5 views
  • 16 May, 2021
  • 5 locations