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Found 102 clinical trials
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Randomised Controlled Study of Physical Exercise Intervention in Breast Cancer Patients at Risk of Anthracycline-induced Cardiomyopathy: The EMBRACE Study

condition can affect as many as 10% of all patients after undergoing anthracycline cancer drug therapy and unfortunately carries the worst prognosis of all cardiomyopathies. To date, there is no effective

Accepts healthy volunteers
antineoplastic
anthracyclines
  • 7 views
  • 06 Oct, 2021
  • 1 location
None
Cancer Activity and Lifestyle Measurement Study

function and overall outcomes for postmenopausal breast cancer patients treated with anthracycline chemotherapy.

anthracyclines
immunostimulant
  • 0 views
  • 25 Jan, 2021
  • 1 location
None
Generation of Heart Muscle Cells From Blood or Skin Cells of Breast Cancer Patients

including anthracycline (e.g. Doxorubicin) and anti-HER2 therapy (e.g. Herceptin) develop decreased heart function.

her2/neu-positive breast cancer
herceptin
trastuzumab
erbb2
anthracyclines
  • 2 views
  • 11 Jun, 2021
  • 1 location
None
Cancer Therapy Effects on the Heart

Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) are commonly given to treat pediatric cancer, and carry a risk of cardiotoxicity. Over the long term, children who receive these

doxorubicin
cancer treatment
daunorubicin
anthracyclines
cancer
  • 6 views
  • 09 May, 2021
  • 1 location
None
Study of Intracellular Nucleotide Pools Determination as Biomarker of the Efficacy of the Induction Treatment in Acute Myeloid Leukemia

nucleoside analog, and an anthracycline (most often daunorubucin). About 60-70% of patients achieved complete remission after this standard chemotherapy. As cytarabine competes with endogenous nucleotides to

induction chemotherapy
hematologic disorder
daunorubicin
cytarabine/daunorubicin
anthracyclines
  • 12 views
  • 06 Aug, 2021
  • 1 location
None
Localized Leiomyosarcoma Biomarker Protocol

metastasis following curative surgery. Clinical trials of neoadjuvant or adjuvant anthracycline and ifosfamide have suggested that patients with localized STS who are at high-risk of metastasis

metastasis
cancer chemotherapy
combination chemotherapy
ifosfamide
immunomodulators
  • 0 views
  • 25 Jun, 2021
  • 4 locations
None
Atherosclerosis in Chemotherapy-related Cardiotoxicity

group of 80 patients diagnosed with cancer before starting high-dose anthracycline chemotherapy (doxorubicin 240 mg / m2 or epirubicin 540 mg / m2 body weight), without a history of heart failure and

infarction
hmg-coa reductase inhibitor
stroke
myocardial infarction
diabetes
  • 0 views
  • 28 Nov, 2021
  • 1 location
None
2D Speckle-tracking Echocardiography in Chemotherapy-induced Cardiomyopathy With Cardiovascular Risk Factors

The aims of this study is to evaluate the role of 2D speckle-tracking echocardiography in diagnosis chemotherapy related left ventricular dysfunction in breast cancer patients with cardiovascular risks

  • 0 views
  • 15 Feb, 2021
  • 1 location
None
Investigating the Long-term Cardiac Sequelae of Trastuzumab Therapy

The introduction of trastuzumab for the treatment of patients with human epidermal growth factor receptor 2 (HER2) positive breast cancer has had a major impact upon cancer outcomes. However, cardiac toxicity remains a substantial concern. Conventionally, this toxicity has been considered as a transient and reversible phenomenon occurring in the …

her2/neu-positive breast cancer
trastuzumab
erbb2
HER2
  • 0 views
  • 30 Aug, 2021
  • 1 location
None
Impact of Neoadjuvant Chemotherapy on the Peripheral Blood Immune Phenotype in Operable Breast Cancer the ENHANCE Study

This early phase I trial evaluates the impact of chemotherapy before surgery (neoadjuvant) on the peripheral blood immune phenotype in patients with operable breast cancer. Collecting blood and information from patients with breast cancer may help to understand how the immune system influences response to treatment, and how the immune …

  • 0 views
  • 18 Jun, 2021
  • 1 location