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Found 103 clinical trials
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Acute Promyelocytic Leukemia 2006 (APL)

, with reduced toxicity and without increasing the relapse rate by comparison with a classical anthracycline-AraC consolidation regimen.

anthracyclines
idarubicin
tretinoin
arsenic
  • 13 views
  • 07 Nov, 2020
  • 1 location
None
Research Study for Treatment of Children and Adolescents With Acute Myeloid Leukaemia 0-18 Years

either standard anthracycline therapy with mitoxantrone or experimental DaunoXome. In the second course patients are randomised between standard treatment with ADxE (cytarabine, DaunoXome, etoposide) or

  • 26 views
  • 21 Jan, 2021
  • 33 locations
None
Multi Centre Trial of DSMM for Newly Diagnosed Multiple Myeloma up to 60 Years

The study is evaluating whether risk-stratification by the means of a chromosomal aberration provides a tool to discriminate between standard and high risk. Risk-adapted therapy is based on allogeneic stem-cell transplantation for high-risk subjects instead of a second autograft in patients with deletion of chromosome 13 who have an HLA-identical …

autograft
cell transplantation
  • 30 views
  • 07 Nov, 2020
  • 15 locations
None
Neoadjuvant Treatment of HER2 Positive Early High-risk and Locally Advanced Breast Cancer

n the present study the neoadjuvant approach with the anti-HER2 trastuzumab and pertuzumab combined with carboplatin and paclitaxel will be used to compare the Event-Free Survival (EFS) in regimens with and without atezolizumab. Following the neoadjuvant part of the study, after surgery all patients will continue to receive trastuzumab and …

trastuzumab
tubal ligation
sentinel node
atezolizumab
paclitaxel
  • 21 views
  • 24 Jan, 2021
  • 51 locations
None
Remote Ischemic Conditioning in Oncology

This is a feasibility study at a single site, Cincinnati Children's Hospital Medical Center. Patients undergoing anthracycline chemotherapy for Hodgkin disease and soft-tissue and bone sarcoma

  • 0 views
  • 26 Jun, 2021
  • 1 location
None
Treatment of Patients With Relapsed or Primary Refractory Aggressive B- Cell NHL

Phase II study for treatment of patients with relapsed or primary refractory aggressive B- cell NHL and anthracycline chemotherapy pretreatment, who received or did not qualify for

anthracyclines
salvage therapy
cell transplantation
bendamustine
rituximab
  • 16 views
  • 07 Nov, 2020
  • 1 location
None
Everolimus (RAD001) and Carboplatin in Pretreated Metastatic Breast Cancer

taxane- and anthracycline-pretreated patients with progressive metastatic breast cancer. Additionally, the study is designed to characterize the safety, the tolerability and efficacy of this

stage iv breast cancer
anthracyclines
carboplatin
taxane
  • 22 views
  • 07 Nov, 2020
  • 1 location
None
Midostaurin Associated With Standard Chemotherapy in Patients With Core-binding Factor Leukemia

investigators believe that Midostaurin, associated with standard therapy Anthracycline/AraC Induction, to the consolidation regimen with high doses of araC and maintenance therapy to single agent in patients

  • 0 views
  • 01 Feb, 2021
  • 2 locations
None
Neoadjuvant Carboplatin in Triple Negative Breast Cancer

neoadjuvant chemotherapy based on anthracycline and taxane, with or without carboplatin.

  • 2 views
  • 23 Jan, 2021
  • 1 location
None
Comparative Study of Scalp Cooling System and Chemical Cold Cap (COHAIR Study)

This is a phase III, single-center, prospective, open-label, randomized,controlled study

  • 11 views
  • 26 Jan, 2021
  • 1 location