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Found 91 clinical trials
Research Study for Treatment of Children and Adolescents With Acute Myeloid Leukaemia 0-18 Years

either standard anthracycline therapy with mitoxantrone or experimental DaunoXome. In the second course patients are randomised between standard treatment with ADxE (cytarabine, DaunoXome, etoposide) or

  • 26 views
  • 21 Jan, 2021
  • 34 locations
Caloric Restriction and Exercise for Protection From Anthracycline Toxic Effects (CREATE)

is to determine whether short-term application of these interventions with specific timing relative to the receipt of each treatment can prevent the negative effects of anthracycline treatment on the

anthracyclines
doxorubicin
breast cancer
cancer
breast cancer staging
  • 143 views
  • 24 Jul, 2022
  • 1 location
A Study of NOX66 Plus Doxorubicin in Anthracycline-naïve, Adult Patients With Soft Tissue Sarcoma

anthracycline therapy, using a fixed dose-escalation schema every 21 days to establish the maximum tolerated dose (MTD) of the combination of NOX66 and doxorubicin.

  • 0 views
  • 23 Jul, 2022
  • 2 locations
Remote Ischemic Conditioning in Oncology (RICO)

This is a feasibility study at a single site, Cincinnati Children's Hospital Medical Center. Patients undergoing anthracycline chemotherapy for Hodgkin disease and soft-tissue and bone sarcoma

  • 0 views
  • 11 Jul, 2022
  • 1 location
Protective Effects of the Nutritional Supplement Sulforaphane on Doxorubicin-Associated Cardiac Dysfunction

Cardiomyopathy is a major complication of doxorubicin (DOX) chemotherapy, and 10-21% of breast cancer patients receiving DOX experience compromised cardiac function. Recent advancements have increased cancer survivorship but it remains clinically challenging to mitigate the cardiotoxic side effects. Although there are several strategies used to reduce the occurrence and severity …

  • 14 views
  • 25 Jul, 2022
  • 1 location
Midostaurin Associated With Standard Chemotherapy in Patients With Core-binding Factor Leukemia (AML FLT3)

investigators believe that Midostaurin, associated with standard therapy Anthracycline/AraC Induction, to the consolidation regimen with high doses of araC and maintenance therapy to single agent in patients

  • 0 views
  • 25 Mar, 2022
  • 1 location
Neoadjuvant Carboplatin in Triple Negative Breast Cancer

neoadjuvant chemotherapy based on anthracycline and taxane, with or without carboplatin.

Accepts healthy volunteers
  • 2 views
  • 24 Feb, 2022
  • 1 location
Fosaprepitant , Tropisetron and Olanzapine for the Prevention of Nausea and Vomiting in Patients With Breast Cancer

Standard antiemetic therapy without dexamethasone for the prevention of nausea and vomiting in patients with breast cancer

  • 0 views
  • 03 May, 2022
  • 2 locations
Comparative Study of Scalp Cooling System and Chemical Cold Cap (COHAIR Study)

This is a phase III, single-center, prospective, open-label, randomized,controlled study

  • 144 views
  • 05 Dec, 2021
  • 1 location
Eribulin in Advanced Solitary Fibrous Tumor (ERASING)

Phase II study on advanced Solitary Fibrous Tumor (SFT) treated with eribulin

  • 6 views
  • 14 Feb, 2022
  • 2 locations