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Found 182 clinical trials
A Study of the Safety Tolerability Pharmacokinetics and Efficacy of Treatment With AP1189 in Patients With iMN

membranous nephropathy (iMN) who are on ACE inhibitor or angiotensin II receptor blocker treatment.

angiotensin
protein creatinine ratio
ace inhibitor
kidney biopsy
nephrotic syndrome
  • 14 views
  • 30 Sep, 2021
  • 1 location
Secondhand Tobacco Smoke and Cardiovascular Disease

This is a double-blind randomized placebo-controlled crossover clinical trial of efficacy and safety of an FDA-approved angiotensin receptor blocker (losartan) to improve cardiopulmonary

losartan
cardiovascular disease
angiotensin
chronic obstructive pulmonary disease
  • 0 views
  • 14 May, 2022
  • 1 location
Bisoprolol for Early Cardiomyopathy in Duchenne Muscular Dystrophy: a Randomized, Controlled Trial

fraction. On top of angiotensin-converting enzyme inhibitor (ACEI) , half of the participants will receive bisoprolol in combination, while the other half will not receive any beta-blocker.

angiotensin
angiotensin converting enzyme
ejection fraction
dmd gene
muscular dystrophy
  • 0 views
  • 14 Oct, 2022
Dapagliflozin in Non-diabetic Stage IV CKD

. Consistently, human studies show that proteinuria is an independent predictor of progression and that its reduction is renoprotective. At comparable BP control, inhibitors of the renin-angiotensin system (RAS

diabetes
hemoglobin a1c
  • 0 views
  • 08 Dec, 2021
  • 1 location
Effect of Losartan on Chronic Obstructive Pulmonary Disease (COPD)

Losartan, an angiotensin receptor blocker, has been effective in preventing the development of emphysema and lung inflammation in animal models of COPD. Moreover, there is epidemiologic

pulmonary disease
emphysema
losartan
COPD
  • 857 views
  • 07 Nov, 2020
  • 1 location
Apelin as a Potential Treatment for Chronic Kidney Disease (AlPaCKa)

aims to reduce blood pressure and proteinuria through the use of angiotensin converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARB). However, many patients still progress to end

endothelial dysfunction
chronic disease
angiotensin
renal function study
arterial stiffness
  • 31 views
  • 25 May, 2022
  • 1 location
Multidiscipline Care for Acute Kidney Disease (AKD)

randomization to add Angiotensin-Converting Enzyme Inhibitors (ACE-I)/Angiotensin II Receptor Blocker (ARB), or by randomization to multidisciplinary care. Patients will be followed up at least 6 months to

aldosterone
dialysis
  • 0 views
  • 06 Oct, 2021
  • 7 locations
Preventing Metabolic Side Effects of Thiazide Diuretics With KMgCitrate

Chlorthalidone (CTD) may produce various metabolic disturbances, including hypokalemia, activation of Renin-Angiotensin- Aldosterone (RAA) system, oxidative stress, dyslipidemia, Fibroblast

dyslipidemia
angiotensin
chlorthalidone
thiazide
renin
  • 24 views
  • 21 Mar, 2022
  • 3 locations
Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum Hypertension

The purpose of this study is to see if a combined pill of Angiotensin-converting enzyme (ACE) inhibitors (a medication that helps relax your veins and arteries to lower your blood pressure) with

  • 0 views
  • 03 Nov, 2021
  • 1 location
Losartan for Diffuse Myocardial Fibrosis in Sickle Cell Disease

This study is a pilot, phase II, open-label study of the angiotensin II receptor blocker, losartan, in patients with Sickle Cell Disease (SCD) 6 years or older for 12 months. The investigators

Accepts healthy volunteers
  • 0 views
  • 26 Jan, 2022
  • 1 location