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Found 154 clinical trials
B-lines-guided Heart Failure Management in Heart Failure Patients (IMP-OUTCOME)

management on outcome for discharged patients with residual B-lines up to 1 year after discharge in the era of sodium-glucose cotransporter-2 inhibitors and angiotensin receptor blocker-neprilysin inhibitor

chronic heart failure
heart failure
  • 29 Apr, 2022
  • 1 location
The Role of Histamine in Breast Cancer Bone Pain

This trial studies histamine and bone pain association in participants with breast cancer that has spread to the bone. Studying histamine levels in samples of blood from participants with breast cancer in the laboratory may help doctors learn more about reducing cancer bone pain and preventing further bone metastasis.

  • 16 Oct, 2022
  • 1 location
Eicosanoids in Human Heart Failure

Our translational project aims to evaluate the role of eicosanoids in human HF.

Accepts healthy volunteers
heart failure
  • 25 Apr, 2022
  • 1 location
Pathophysiologic Hemodynamics After Primary Unilateral Total Hip Arthroplasty in Patients Receiving ACEIs and ARBs

Incidence and pathophysiologic hemodynamics of postoperative orthostatic intolerance and orthostatic hypotension in patients receiving antihypertensives

  • 21 Apr, 2021
  • 1 location
Fractional Excretion of Urea for the Differential Diagnosis of Acute Kidney Injury in Cirrhosis

The aim of this study is to evaluate: The diagnostic performance of Fractional Excretion of Urea (FEUrea) for the differential diagnosis of acute kidney injury in patients with cirrhosis and ascites presenting to a tertiary care hospital. The ability of Fractional Excretion of Urea to distinguish between structural group of …

  • 04 Oct, 2021
  • 1 location
Effect of Intensive Medical Treatment on Quantified Coronary Artery Plaque Components With Serial Coronary CTA in Women With NonObstructive CAD

In this study, quantitative characterization of plaque using coronary computed tomographic angiography (CTA) will be used to determine if women who were treated with intensive medical therapy have a greater reduction in the amount and type of cholesterol plaque compared to women receiving usual care and if this results in …

  • 18 Oct, 2022
  • 1 location
Long COVID-19 Fatigue and Obstructive Sleep Apnea (PostCoV2OSA)

Identify the relationship of obstructive sleep apnea (OSA) prevalence with post-COVID-19 fatigue that remains at least six months after acute disease

  • 20 Apr, 2022
  • 10 locations
Pilot Study of Cardiac MR in Patients With Muscular Dystrophy

Muscular Dystrophy can affect the skeletal muscles and also the heart and breathing muscles, causing significant morbidity and mortality. As patients are now living longer, treatment of muscular dystrophies involves drugs that help improve heart function. However, better types of heart imaging studies are needed to understand how these treatments …

limb-girdle muscular dystrophy
heart imaging
muscular dystrophy
  • 11 Mar, 2022
  • 1 location
LOnger-term Effects of COVID-19 INfection on Blood Vessels And Blood pRessure (LOCHINVAR) (LOCHINVAR)

The COVID-19 pandemic is the biggest medical challenge in decades. Individuals with pre-existing cardiovascular diseases have a higher risk of severe disease and death from COVID-19. The SARS-CoV-2 virus causes infection by targeting a molecule on the walls of the cells lining the lungs and the blood vessels leading to …

antihypertensive drugs
  • 13 May, 2022
  • 1 location
Effects of Sarilumab on Interleukin 6 Levels in Critically Ill COVID-19 Patients

Investigate the possible effects of interleukin-6 receptor antagonists such as tocilizumab and sarilumab on the levels of IL-6 before and after treatment in critically ill corona virus disease-19 patients. Correlate between IL-6 levels with other inflammatory markers as ferritin and C-reactive protein.

  • 25 Oct, 2022
  • 1 location