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Found 63 clinical trials
Featured trial
Marfan Syndrome (MFS) Medication Study

Marfan Syndrome (MFS) Medication Study

  • 88 views
  • 25 Mar, 2021
  • 1 location
None
A Randomized Open-label LOSARTAN Therapy on the Progression of Aortic Root Dilation in Patients With Marfan Syndrome

To assess the efficacy of angiotensin II receptor blocker, Losartan, to prevent progressive dilation of aortic root in patients with Marfan syndrome.

  • 0 views
  • 07 Nov, 2020
None
Renin Angiotensin System Blockade in Renal Transplant Patients With Presence of PECs in Urine

By means of a personalized medicine strategy, investigators are going to evaluate if the treatment with an angiotensin II receptor antagonist (ARAII) in renal transplant patients with the

  • 0 views
  • 27 May, 2021
  • 1 location
None
Nebivolol Versus Losartan Versus Nebivolol+Losartan Against Aortic Root Dilation in Genotyped Marfan Patients

death in MFS is TGFb which is antagonised by existing drugs employed in the clinical practice, the Angiotensin II receptor blockers (ARB).

  • 160 views
  • 07 Nov, 2020
  • 1 location
None
The Potential of Candesartan to Retard the Progression of Aortic Stenosis

The present study defines a blinded, randomized, placebo-controlled, prospective study, the aim of which is to determine the influence of effective treatment with Type 1 angiotensin II

angiotensin ii
fibrosis
stenotic
  • 9 views
  • 07 Nov, 2020
  • 1 location
None
Losartan for Improved Vascular Endothelial Function After Preeclampsia

mechanisms contributing to this lasting blood vessel damage and to test whether taking a medication that blocks angiotensin II receptors (losartan) decrease these negative effects in women who have had

  • 0 views
  • 30 Jan, 2021
  • 1 location
None
Explorative Study for Treating Persistent Developmental Stuttering With Ramipril

>Angiotensin receptors are present in the striatum Angiotensin causes elevated striatum dopamine levels ACE inhibitors penetrate the blood brain barrier and reduce brain angiotensin II levels

  • 0 views
  • 17 Feb, 2021
  • 2 locations
None
A Comparison of Hydrochlorothiazide and Metolazone in Combination With Furosemide in Congestive Heart Failure Patients

The purpose of this research study is to compare the effectiveness of hydrochlorothiazide or metolazone in combination with furosemide. Patients with heart failure suffer from swelling because of too much fluid in the body. Furosemide, hydrochlorothiazide, and metolazone are all water pills used to treat the swelling. For most patients, …

ejection fraction
beta-adrenergic blocking agents
congestive heart failure
diuretics
edema
  • 8 views
  • 07 Nov, 2020
  • 1 location
None
Intracoronary Infusion of Mononuclear Cells Autologous Bone Marrow in Patients With Chronic Coronary Occlusion and Ventricular Dysfunction Previously Revascularized.

Clinical trial phase III, prospective, controlled, randomized, open. We hypothesize work that patients with chronic coronary occlusion and poor myocardial viability who failed to recover ventricular function after subjecting coronary revascularization with new techniques of recanalization, could achieve an improvement of ventricular function if given further regenerative treatment with mononuclear …

  • 33 views
  • 20 Mar, 2021
  • 3 locations
None
ARNI in Asymptomatic Patients With Elevated Natriuretic Peptide and Elevated Left Atrial Volume Index eLEvation

The purpose of this study is to determine whether LCZ696 (valsartan/sacubitril) is safe and has beneficial effects on the heart and blood vessels in patients with high blood pressure and/or diabetes or other risk factors for developing heart failure (elevated levels of natriuretic peptide and elevated left atrial volume index). …

valsartan
heart failure
sacubitril
diabetes
natriuretic peptide
  • 0 views
  • 08 Nov, 2020
  • 1 location