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Found 6 clinical trials
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Study Evaluating the Safety and Efficacy of C-CHOP in Untreated Subjects With Angioimmunoblastic T Cell Lymphoma

This is a single-arm, open-label phase 2study of Chidamide in combination with CHOP in the treatment of subjects with untreated angioimmunoblastic T cell lymphoma.

cyclophosphamide
prednisone
doxorubicin
measurable disease
lymphoma
  • 0 views
  • 23 Jan, 2021
None
Study of Lacutamab in Peripheral T-cell Lymphoma

/Relapsing (R/R) KIR3DL2 positive Peripheral T Cell Lymphoma (PTCL) : Not Other Specified (NOS), PTCL-TFH (including Angioimmunoblastic T-cell Lymphoma (AITL), Follicular T-cell lymphoma, Nodal peripheral T

t-cell leukemia
measurable disease
leukemia
peripheral t-cell lymphoma
stem cell transplantation
  • 0 views
  • 15 Dec, 2021
  • 37 locations
None
Pembrolizumab and Pralatrexate in Treating Patients With Relapsed or Refractory Peripheral T-Cell Lymphomas

This phase I/II trial studies the side effects and best dose of pralatrexate when given together with pembrolizumab and how well they work in treating patients with peripheral T-cell lymphomas that has come back after a period of improvement or has not responded to treatment. Pralatrexate may stop the growth …

direct bilirubin
mycosis fungoides
enteropathy
measurable disease
peripheral t-cell lymphoma
  • 3 views
  • 20 Aug, 2021
  • 3 locations
None
Sintilimab Combined With Chidamide in Treating Peripheral T Cell Lymphoma

This is a single-center, single-arm, phase 2 study to evaluate the efficacy and safety of Anti-PD-1 antibody(Sintilimab) plus HDAC inhibitor(Chidamide) in patients with relapsed/refractory peripheral T-cell lymphoma (r/r PTCL).

peripheral t-cell lymphoma
measurable disease
anaplastic large cell lymphoma
renal function
large cell lymphoma
  • 0 views
  • 16 Dec, 2021
  • 1 location
None
Combination Chemotherapy Including Cisplatin Ifosfamide Gemcitabine L-asparaginase Etoposide and Dexamethasone as Treatment of Newly Diagnosed and Relapsed/Refractory Peripheral T Cell Lymphomas

The PIGLETS regimen was devised to replace the conventional SMILE regimen in management of extranodal NK/T cell lymphoma in our institution. It had been three years since the introduction of PIGLETS regimen in treatment of NK malignancies. The response rate is encouraging, with an overall response rate (ORR) of 90% …

t-cell lymphoma
etoposide
dexamethasone
cancer
  • 2 views
  • 22 Jan, 2021
None
Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

This phase II trial studies the effect of duvelisib or CC-486 and usual chemotherapy consisting of cyclophosphamide, doxorubicin, vincristine, etoposide, and prednisone in treating patients with peripheral T-cell lymphoma. Duvelisib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such …

platelet count
peripheral t-cell lymphoma
mycosis fungoides
hormonal therapy
measurable disease
  • 0 views
  • 19 Jan, 2022
  • 7 locations