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Found 562 clinical trials
Treatment of In-Stent Restenosis 2 Study

The aim of this study is to compare the efficacy of sirolimus-eluting balloon catheters (SEB) and iopromide-coated paclutaxel-eluting balloon catheters (PEB) in the treatment of bare metal (BMS) - or drug-eluting stents restenosis (DES-ISR).

paclitaxel
sirolimus
in stent restenosis
  • 2 views
  • 25 Feb, 2021
  • 1 location
Permanent Cerebral Oxymetry Monitoring for Early Diagnosis and Treatment of Delayed Vasospasm After Subarachnoid Hemorrhage

Transcranial Doppler ultrasound (TCD) monitoring and CT-scanner perfusion are useful but imperfect tools to identify vasospasm and allow intervention to avoid infarction. Permanent monitoring of cerebral tissue oximetry (rSO2) by NIRS, a noninvasive method could allow better vasospasm detection. This study will evaluate diagnostic accuracy of cerebral oxymetry (NIRS) -by …

vasospasm
transcranial doppler ultrasound
  • 0 views
  • 23 Jan, 2021
  • 1 location
The Potential of Candesartan to Retard the Progression of Aortic Stenosis

The present study defines a blinded, randomized, placebo-controlled, prospective study, the aim of which is to determine the influence of effective treatment with Type 1 angiotensin II (Ang II) receptor (AT-1R) antagonist, using candesartan (target dose 16 mg) on stenotic aortic valves. The investigators will specifically quantify whether candesartan attenuates …

stenotic
angiotensin ii
fibrosis
  • 9 views
  • 07 Nov, 2020
  • 1 location
Middle Meningeal Artery Embolization With Liquid Embolic Agent for Treatment of Chronic Subdural Hematoma

The study evaluates the clinical and imaging outcome of middle meningeal artery (MMA) embolization with liquid embolic agent for treatment of chronic subdural hematoma (CSDH)

  • 0 views
  • 26 Jan, 2021
  • 1 location
CB-PRP in Retinitis Pigmentosa

The study will provides the enrollment of patients with genetic retinal dystrophies with primary rod impairment. A subretinal injection of umbilical cord blood platelet-rich plasma (CB-PRP) will be performed only in one eye, the other eye will be considered as a control group. A complete morpho-functional ophthalmological evaluation will be …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Evaluation of the Efficacy and Safety of the Application of BeGraft Peripheral Stent Graft System

The trial will be conducted to evaluate the safety and efficacy of the BeGraft Peripheral Stent Graft System in interventional revascularisation for subjects with primary iliac artery stenosis and/or occlusive lesions by conducting a multi-centre, randomised controlled clinical study with a bare metal stent system as the control, thus providing …

  • 0 views
  • 23 Jan, 2021
  • 12 locations
Clinical Study of Thoracic Aortic Aneurysm Exclusion

The Valiant stent-graft system is a flexible, implantable vascular stent-graft endoluminal device preloaded in a delivery system that is used to exclude thoracic aortic lesions (thoracic aneurysms, thoracic dissections, penetrating ulcers, traumatic transections and both traumatic and degenerative pseudoaneurysms.

aortic dissection
ct scan
pseudoaneurysm
dissections
  • 23 views
  • 07 Nov, 2020
  • 1 location
Treatment of Central Retinal Vein Occlusion Using Stem Cells Study

This study evaluates whether intravitreal autologous CD34+ stem cell therapy is safe, feasible and potentially beneficial in eyes with vision loss from central retinal vein occlusion (CRVO). Half of the participants will receive immediate cellular therapy followed by sham therapy 6 months later, while the other half will receive immediate …

venous obstruction
blindness
sham therapy
stem cell therapy
  • 0 views
  • 24 Jan, 2021
  • 1 location
A Study to Evaluate Direct Wire Pacing (DWP) for Measuring Fractional Flow Reserve (FFR)

This is a randomized, non-inferiority, crossover investigation comparing the Direct Wire Pacing (DWP) versus standard method to measure Fractional Flow Reserve (FFR) in subjects with FFR indications. All subjects requiring on a clinical basis a pressure wire assessment of coronary artery stenosis(es) will be eligible to take part in the …

  • 0 views
  • 31 Jul, 2021
  • 1 location
Doxycycline for Hereditary Hemorrhagic Telangiectasia

This study will investigate the effectiveness of oral doxycycline for the treatment of recurrent nasal hemorrhage in Hereditary Hemorrhagic Telangiectasia (HHT) subjects. The primary outcome for the trials will be the reduction of epistaxis severity (minutes of bleeding per week). The biological outcomes of interest are the regression of vascular …

  • 2 views
  • 25 Jan, 2021
  • 1 location