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Found 229 clinical trials
Precision Medicine With Zibotentan in Microvascular Angina

Microvascular angina (MVA) is caused by abnormalities of the small vessels in the heart. Endothelin is a small chemical that circulates and accumulates in the blood vessel walls, causing them to

  • 0 views
  • 26 Jan, 2021
  • 1 location
Adenovirus Vascular Endothelial Growth Factor D (AdvVEGF-D) Therapy for Treatment of Refractory Angina Pectoris (ReGenHeart)

patients with refractory angina to whom revascularisation cannot be performed.

angiography
stenosis
angina pectoris
exercise stress test
bypass graft
  • 6 views
  • 28 Feb, 2022
  • 2 locations
Efficacy of Spinal Cord Stimulation in Patients With Refractory Angina Pectoris (SCRAP)

There are a growing number of patients with refractory angina pectoris (RAP). RAP is defined as a 'chronic condition (> three months) characterized by diffuse coronary artery disease in the

  • 0 views
  • 20 Apr, 2022
  • 1 location
A Placebo-controlled Trial of Percutaneous Coronary Intervention for the Relief of Stable Angina

ORBITA-2 is a double blinded randomised placebo-controlled trial comparing the effects of coronary angioplasty versus placebo procedure on symptoms of stable angina without background anti

cardiac mri
coronary artery stenosis
ischemia
stenosis
stress echocardiography
  • 60 views
  • 01 Sep, 2021
  • 8 locations
Safety and Efficacy of Low Temperature Contrast in UAP Patients During PCI (LOTA-I)

, many studies have found that the incidence of PCI-related myocardial injury is relatively high, and affect the efficacy of PCI and prognosis in patients with unstable angina pectoris (UAP). A meta

heart disease
unstable angina
percutaneous coronary intervention
angina pectoris
  • 36 views
  • 06 May, 2022
  • 9 locations
A Placebo-controlled Trial of Chronic Total Occlusion Percutaneous Coronary Intervention for the Relief of Stable Angina

ORBITA-CTO Pilot is a double blinded randomised placebo-controlled trial comparing the effects of chronic total occlusion percutaneous coronary intervention versus placebo on symptoms of angina

percutaneous coronary intervention
stable angina
  • 0 views
  • 08 Dec, 2021
  • 2 locations
PRIZE ET Sub-Study

Microvascular angina (MVA) is caused by abnormalities of the small blood vessels in the heart. Endothelin-1 (ET-1) is a chemical messenger that circulates and accumulates in the blood vessel

exercise stress test
bruce
exercise ecg
  • 0 views
  • 01 Oct, 2021
  • 1 location
Physiology as Guidance to Evaluate the Direct Impact of Coronary Lesion Treatment: The PREDICT Study (EASY-PREDICT)

(TVF) and angina-related events than standard angiographic guidance.

angiography
stenosis
  • 0 views
  • 25 Mar, 2022
  • 1 location
Use of the Neovasc Coronary Sinus Reducer System for the Treatment of Refractory Angina Pectoris in Patients With Ngina Class 3-4 Who Are Not Candidates for Revascularization (Reducer)

The purpose of this study is to implant the Reducer in patients with the symptoms of refractory angina, that suffer from refractory angina who demonstrate reversible ischemia.

  • 106 views
  • 24 Mar, 2022
  • 2 locations
Coronary Sinus Reducer Objective Impact on Symptoms MRI Ischaemia and Microvascular Resistance

perfusion on MRI, exercise time and symptoms in 40 participants with refractory angina and ischaemia.

  • 0 views
  • 08 Sep, 2021
  • 5 locations