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Found 235 clinical trials
Beta-blockers to Patients With Chronic Obstructive Pulmonary Disease

Background: In patients with chronic obstructive pulmonary disease (COPD) and concomitant cardiovascular conditions cardio-selective beta-blockers reduce mortality and can be used without significant negative effects on lung function or respiratory symptoms. Observational studies indicate that beta-blocker therapy in COPD even without overt cardiovascular disease, is associated with reduced risk for …

asthma
spirometry
pulmonary function test
respiratory symptom
bronchodilator
  • 21 views
  • 18 May, 2022
  • 1 location
BEtablocker Treatment After Acute Myocardial Infarction in Patients Without Reduced Left Ventricular Systolic Function (BETAMI)

The study aims to investigate whether oral betablocker (BB) therapy is superior to no such treatment following an acute myocardial infarction (AMI).

bundle branch block
ischemia
clot
q waves
secondary prevention
  • 0 views
  • 14 Feb, 2022
  • 4 locations
Heart Disease of the Small Arteries in Women and Men

Women suffer disproportionately than men from Cardiac Syndrome X ( chest pain in the absence of flow limiting coronary artery stenosis). Coronary microvascular disease is hypothesized to mediate chest pain in this syndrome. This disorder of the small heart vessels (arterioles) compared to the large vessels (arteries) is not diagnosed …

angina pectoris
ischemia
hmg-coa reductase inhibitors
coronary disease
hmg-coa reductase inhibitor
  • 11 views
  • 23 Jan, 2022
  • 1 location
Dual Antithrombotic Therapy With Dabigatran and Ticagrelor in Patients With ACS and Non-valvular AF Undergoing PCI

More than 25% of patients referred for diagnostic coronary angiography and percutaneous coronary intervention (PCI) due to acute coronary syndrome (ACS) suffer from non-valvular atrial fibrillation (AF). In this particular setting, balancing between the prevention of thrombosis and the risk of bleeding remains challenging. Oral anticoagulation (OAC) prevents stroke and …

ticagrelor
fibrillation
bypass graft
transient ischemic attack
dabigatran
  • 0 views
  • 12 Nov, 2021
  • 1 location
Treatment of Hypertension During Sleep (THADEUS)

On the basis of new evidence on the relationship between achieved office blood pressure (BP) measurements (OBPM) and the risk of cardiovascular disease (CVD) morbidity and mortality documented in the SPRINT trial, the recent 2017 guidelines of the American College of Cardiology (ACC) and the American Heart Association (AHA) have …

cardiovascular disease
systolic blood pressure
hypertension
blood pressure diastolic
ambulatory blood pressure monitoring
  • 63 views
  • 27 Feb, 2022
  • 9 locations
Direct Complete Versus Staged Complete Revascularization in Patients Presenting With Acute Coronary Syndromes and Multivessel Disease (BioVasc)

To test whether immediate complete revascularization is non-inferior to staged (but within six weeks after index procedure) complete revascularization in Patients presenting with ACS, including Non-ST-elevation ACS (NSTEACS) and ST-elevation myocardial infarction (STEMI), with multivessel disease accepted for PCI

creatine kinase mb
angina pectoris
ischemia
stemi
infarct
  • 0 views
  • 12 Feb, 2022
  • 1 location
Aspirin to Target Arterial Events in Chronic Kidney Disease (ATTACK)

This study aims to find out whether people with chronic kidney disease [CKD] should take low dose aspirin to reduce the risk of first heart attack or stroke (cardiovascular disease [CVD]). CKD is common and is associated with an increased risk of CVD. CVD is caused by small blood clots …

cardiovascular disease
proteinuria
clot
glomerular filtration rate
primary prevention
  • 0 views
  • 25 Mar, 2022
  • 1 location
Coronary Microvascular Angina Cardiac Magnetic Resonance Imaging (CorCMR) Trial

Anginal symptoms due to ischaemia with no obstructive coronary arteries (INOCA) is a common clinical problem, however, diagnosis and onward management is heterogeneous, and prognosis is affected. Recent advances in quantifying myocardial blood flow using stress perfusion cardiac magnetic resonance imaging (CMR) has potential for accurate detection coronary microvascular dysfunction. …

  • 0 views
  • 27 Mar, 2021
  • 1 location
Percutaneous Coronary Intervention Versus Medical Treatment for Stable Angina Pectoris

Patients with ischemic heart disease and symptoms due to lack of oxygen to the heart on exertion (stable angina pectoris) are usually treated by either percutaneous coronary intervention (PCI

coronary artery disease
revascularisation
stable angina
medical therapy
arterial disease
  • 0 views
  • 25 Jan, 2021
  • 1 location
Precision Medicine With Zibotentan in Microvascular Angina

Microvascular angina (MVA) is caused by abnormalities of the small vessels in the heart. Endothelin is a small chemical that circulates and accumulates in the blood vessel walls, causing them to

  • 0 views
  • 26 Jan, 2021
  • 1 location