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Found 231 clinical trials
Surgical Treatment of Tonsillar Abscess

The diagnosis and treatment of tonsillar abscess are very physician-dependent, as sufficient prospective medical literature is lacking to choose the most efficient regimen. The proposed study aims to assess the therapeutic efficacy of tonsillectomy compared to drainage under local anesthesia. This is a prospective, randomized clinical trial in adults in …

  • 0 views
  • 15 May, 2021
  • 1 location
Tailoring Pacemaker Output to Physiology in Chronic Heart Failure

Aims: To explore the clinical effect on exercise tolerance and quality of life, safety and tolerability of pacing at higher outputs in patients with chronic heart failure and a pacemaker. Background: Heart failure (HF) is a very common condition of breathlessness or fatigue associated with heart muscle weakness. In around …

systolic dysfunction
weakness
exercise test
dyspnea
left ventricular systolic dysfunction
  • 0 views
  • 02 Mar, 2022
  • 1 location
iCorMicA - Stratified Medicine in Angina

medical therapy guided by an adjunctive interventional diagnostic procedure (IDP) during the invasive management of patients with known or suspected angina but no obstructive coronary artery disease

  • 0 views
  • 27 Jan, 2021
  • 2 locations
Cost-effectiveness and Safety of the CADScorSystem in Patients With Symptoms Suggestive of Stable Coronary Artery Disease. (FILTER-SCAD)

This study evaluates the addition of the CADScorSystem to a standard Diamond-Forrester score guided rule-out strategy in ambulatory patients referred with symptoms suggestive of stable coronary artery disease. Half of the patients will undergo stratification using a Diamond-Forrester score only, while the other half will undergo stratification using a Diamond-Forrester …

myocardial infarction
artery disease
infarct
  • 0 views
  • 16 Mar, 2022
  • 8 locations
Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial (HOST-IDEA)

(DAPT) for these stent systems still needs to be established. With a 2x2 factorial design for patients of stable angina or silent ischemia, the investigators formulate a head-to-head randomized

antiplatelet therapy
myocardial infarction
infarct
stenosis
ischemia
  • 0 views
  • 26 Jan, 2022
  • 4 locations
Evaluation of Safety and Efficacy of Two Ticagrelor-based De-escalation Antiplatelet Strategies in Acute Coronary Syndrome (ELECTRA-SIRIO)

The ELECTRA-SIRIO 2 study is a randomized, multicenter, double-blind, investigator-initiated clinical trial aimed to evaluate safety and efficacy of two ticagrelor-based de-escalation antiplatelet strategies in patients with acute coronary syndrome (ACS). During the hospitalization due to ACS, participants will be randomized in a 1:1:1 ratio into one of three arms: …

ticagrelor
antiplatelet therapy
acute coronary syndrome
aspirin
  • 0 views
  • 13 Mar, 2022
  • 1 location
Edoxaban Versus Edoxaban With antiPlatelet Agent In Patients With Atrial Fibrillation and Chronic Stable Coronary Artery Disease (EPIC-CAD)

This study evaluates the efficacy and safety of Edoxaban with the combination of edoxaban and antiplatelet in patients with stable CAD (coronary artery stenosis 50% on medical treatment or revascularized stable CAD [ 12 months for acute coronary syndrome and 6 months after stable CAD]) and high-risk atrial fibrillation (CHA2DS2-VASc …

acute coronary syndrome
revascularisation
fibrillation
percutaneous coronary intervention
angina pectoris
  • 51 views
  • 09 Feb, 2022
  • 8 locations
PRospective Evaluation of Complete Revascularization in Patients With multiveSsel Disease Excluding chroNic Total Occlusions (PRESENT)

guidance (OCT) in patients with multivessel coronary artery disease including left anterior descending (LAD) presenting with stable angina, or documented silent ischemia, or non-ST segment elevation acute

acute coronary syndrome
revascularisation
zotarolimus
onyx
ischemia
  • 0 views
  • 22 Mar, 2022
  • 1 location
The Flash FFR Ⅱ Study

The overall purpose of Flash FFR Ⅱ is to investigate whether coronary angiography-derived fractional flow reserve (caFFR), compared with fractional flow reserve (FFR) measured by a pressure wire, has non-inferior clinical effect and cost benefit in guiding the percutaneous coronary intervention (PCI) for patients with moderate coronary artery stenosis in …

myocardial infarction
heart disease
infarct
unstable angina
ischemia
  • 0 views
  • 24 Mar, 2022
  • 10 locations
Abnormal Coronary Vasomotion in Patients With Suspected Coronary Artery Disease (CAD) (ACOVA)

In patients with chest pain and/or shortness of breath coronary artery disease (CAD) is suspected depending on the pattern of symptoms and the electrocardiogram (ECG). Coronary angiography is the method of choice to verify this suspicion. If the patient coronary arteries on coronary angiography are totally normal or unobstructed, one …

angiography
ischemia
artery disease
chest pain
angina pectoris
  • 119 views
  • 25 Mar, 2022
  • 1 location