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Found 40 clinical trials
SC IL-1Ra in SAH - Phase III Trial (SCIL) (SCIL)

This phase III trial will establish whether IL-1Ra, with sub-cutaneous (SC) administration twice daily for up to 21 days post aneurysmal subarachnoid haemorrhage (aSAH), improves clinical

withdrawn
  • 59 views
  • 04 Jun, 2022
  • 12 locations
Intraventricular Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage. (FIVHeMA)

Aneurysmal subarachnoid hemorrhage (SAH) is a devastating form of stroke, with delayed cerebral ischemia (DCI) as a major complication. There are several evidences, both in preclinical and in

intracranial aneurysm
cerebral infarction
fibrinolysis
tissue plasminogen activator
aneurysmal subarachnoid hemorrhage
  • 1 views
  • 13 Feb, 2022
  • 1 location
Prediction of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage Using Dynamic 18F-FDG PET/CT (PREDISP)

A pilot trial for assessing early microvascular alterations after aneurysmal subarachnoid hemorrhage using dynamic 18F-FDG PET/CT. The primary endpoint will be the measure of early changes in

  • 0 views
  • 02 May, 2022
Triggers And Risk Factors to Develop a Reversible Cerebral Vasoconstriction Syndrome (TARDIS)

This study will be the first to evaluate the role played by potential precipitating factors and risk factors in Reversible Cerebral Vasoconstriction Syndrome (RCVS) through of prospective selection of carefully characterised patients and controls. The impact of these factors on the prognosis will be evaluated through a follow-up assessment of …

Accepts healthy volunteers
  • 0 views
  • 20 Feb, 2022
  • 1 location
The ETCHES I Study (Endovascular Treatment of Communicating Hydrocephalus With an Endovascular Shunt) (ETCHES I)

The eShunt™ System is a minimally invasive method of treating communicating hydrocephalus. The eShunt System includes a proprietary eShunt Delivery System and the eShunt Implant, a permanent implant deployed in a minimally invasive, neuro-interventional procedure. The eShunt Implant is designed to drain excess cerebrospinal fluid (CSF) from the intracranial subarachnoid …

  • 0 views
  • 13 Apr, 2022
  • 1 location
Prediction for Coma Recovery With Comaweb (COMASCORE)

outcome of patients unresponsive to simple orders after traumatic brain injury (TBI), aneurysmal subarachnoid hemorrhages (aSAH) and cardiac arrest (CA) in the day 7 - day 45 period post brain injury.

Accepts healthy volunteers
traumatic brain injury
MRI
coma
cardiac arrest
  • 4 views
  • 25 Feb, 2022
  • 1 location
Cilostazol and Nimodipine Combined Therapy After Aneurysmal Subarachnoid Hemorrhage (aSAH)

The investigators seek to demonstrate that the combined use of cilostazol and nimodipine will significantly decrease the rate of delayed cerebral infarction and cerebral vasospasm after cerebrovascular intervention when compared to nimodipine alone.

  • 2 views
  • 21 Mar, 2022
  • 1 location
Deferoxamine In the Treatment of Aneurysmal Subarachnoid Hemorrhage (aSAH) (DISH)

Aneurysmal subarachnoid hemorrhage (aSAH) has a high incidence of mortality and significant morbidity, with mortality exceeding 30% in the first two days.The initial injury is related to

  • 10 views
  • 25 Apr, 2022
  • 1 location
Fight INflammation to Improve Outcome After Aneurysmal Subarachnoid HEmorRhage (FINISHER)

Aneurysmal subarachnoid hemorrhage (SAH) is a fatal disease with high morbidity and mortality. While the primary injury results from the initial bleeding and cannot be influenced, secondary

  • 0 views
  • 03 Jun, 2022
  • 7 locations
Danish RAndomized Trial of External Ventricular Drainage Cessation IN Aneurysmal Subarachnoid Haemorrhage (DRAIN)

To assess the benefits and harms of two commonly used regimens for external ventricular drainage cessation in in patients with hydrocephalus following aneurysmal subarachnoid haemorrhage a

drainage
  • 3 views
  • 10 May, 2022
  • 1 location