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Found 46 clinical trials
SC IL-1Ra in SAH - Phase III Trial (SCIL)

This phase III trial will establish whether IL-1Ra, with sub-cutaneous (SC) administration twice daily for up to 21 days post aneurysmal subarachnoid haemorrhage (aSAH), improves clinical

withdrawn
  • 59 views
  • 07 Oct, 2021
  • 11 locations
Integrated Platform for Multimodal Patient Monitoring and Therapy Support in ICU Patients

In neurocritical care, besides the standard intensive care monitoring, even more data are obtained from the very complex pathophysiological changes in brain disease. Medical staff for decision-making cannot integrate the huge amount of clinical data generated every second and visualized on different monitors, anymore. Lack of data integration and usability …

  • 0 views
  • 09 Apr, 2021
  • 1 location
Intraventricular Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage.

Aneurysmal subarachnoid hemorrhage (SAH) is a devastating form of stroke, with delayed cerebral ischemia (DCI) as a major complication. There are several evidences, both in preclinical and in

fibrinolysis
intracranial aneurysm
aneurysmal subarachnoid hemorrhage
hydrocephalus
delayed cerebral ischaemia
  • 1 views
  • 04 Jul, 2021
  • 1 location
Prediction of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage Using Dynamic 18F-FDG PET/CT

A pilot trial for assessing early microvascular alterations after aneurysmal subarachnoid hemorrhage using dynamic 18F-FDG PET/CT. The primary endpoint will be the measure of early changes in

  • 0 views
  • 08 Jan, 2022
  • 1 location
Triggers And Risk Factors to Develop a Reversible Cerebral Vasoconstriction Syndrome

This study will be the first to evaluate the role played by potential precipitating factors and risk factors in Reversible Cerebral Vasoconstriction Syndrome (RCVS) through of prospective selection of carefully characterised patients and controls. The impact of these factors on the prognosis will be evaluated through a follow-up assessment of …

  • 0 views
  • 03 Feb, 2021
  • 1 location
The ETCHES I Study (Endovascular Treatment of Communicating Hydrocephalus With an Endovascular Shunt)

The eShunt™ System is a minimally invasive method of treating communicating hydrocephalus. The eShunt System includes a proprietary eShunt Delivery System and the eShunt Implant, a permanent implant deployed in a minimally invasive, neuro-interventional procedure. The eShunt Implant is designed to drain excess cerebrospinal fluid (CSF) from the intracranial subarachnoid …

  • 0 views
  • 20 Jan, 2022
  • 1 location
Clinical Research Study With Clazosentan to Evaluate Its Effects on Preventing Complications Due to the Narrowing of the Blood Vessels (Vasospasm) in the Brain Caused by Bleeding Onto the Surface of the Brain

This study will evaluate if clazosentan (on top of normal routine medical care) can reduce the risk of developing complications related to cerebral vasospasm and permanent brain damage as compared to normal routine medical care alone.

  • 36 views
  • 19 Jan, 2022
  • 232 locations
Prediction for Coma Recovery With Comaweb

outcome of patients unresponsive to simple orders after traumatic brain injury (TBI), aneurysmal subarachnoid hemorrhages (aSAH) and cardiac arrest (CA) in the day 7 - day 45 period post brain injury.

cardiac arrest
traumatic brain injury
coma
MRI
  • 4 views
  • 23 Jan, 2021
  • 1 location
CorPath® GRX Neuro Study

The primary objective of this study is to evaluate the effectiveness and safety of robotic-assisted endovascular embolization procedures compared to objective performance criteria for traditional, manual operation based on the scientific literature.

aneurysm
Accepts healthy volunteers
embolization procedure
cerebral aneurysm
endovascular procedure
  • 4 views
  • 19 Jan, 2022
  • 9 locations
Aneurysmal Subarachnoid Hemorrhage Trial RandOmizing Heparin

A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients with

anesthesia
clot
global aphasia
angiography
heparin
  • 19 views
  • 26 Aug, 2021
  • 10 locations