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Found 429 clinical trials
Evaluate the Use of Glibenclamide on Acute aSAH

A randomized, open-labeled, blank-controlled and prospective trial meant to evaluate the use of glibenclamide on acute aneurysmatic subarachnoid hemorrhage. Patients will allocated randomly in two groups, one for 3.75 mg daily intake of glibenclamide for 7 days and another as a blank contrast. General clinical data and late cognitive status …

  • 25 Mar, 2022
  • 1 location
The CASPER Registry

The CASPER study is a prospective, international, multicenter registry which aims to evaluate the use of an algorithm for choosing the size of the prosthesis to be implanted in patients with bicuspid aortic stenosis type I treated by TAVI with Evolut® Pro prostheses (23 -26-29) and Evolut® R 34.

  • 09 Jun, 2022
  • 1 location
The DISSECT Study: Effect of Peri-aDventItial SMA diSsECtion on Margin sTatus During Pancreaticoduodenectomy for Resectable Pancreatic Cancer

There is a high rate of R1 resection following patients undergoing pancreaticoduodenectomy for pancreatic cancer. The most commonly positive margin is the SMA. Peri-adventitial dissection has been proposed as an effective method of achieving R0 margins. There is lack of standardisation of the proposed technique and no grade 1 evidence …

  • 04 Jun, 2021
  • 1 location
Trial of Maternal Oxygen for Fetal Left Heart Hypoplasia

The purpose of this study is to determine if maternal hyperoxygenation is an effective treatment for fetal left heart hypoplasia versus room air (placebo). This will be determined by measuring how well a baby's heart valves and their surrounding tissue are growing and functioning. In addition the investigators will examine …

  • 08 Dec, 2021
  • 1 location
Prediction of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage Using Dynamic 18F-FDG PET/CT (PREDISP)

A pilot trial for assessing early microvascular alterations after aneurysmal subarachnoid hemorrhage using dynamic 18F-FDG PET/CT. The primary endpoint will be the measure of early changes in cerebral glucose uptake reflecting microperfusion.

  • 02 May, 2022
Comprehensive Aneurysm Management Trial (CAM)

The uncertainty regarding the management of Unruptured Intracranial Aneurysms (UIAs) has not progressed in the last 30 years. The fundamental ethical basis for this study is that physicians

  • 19 Jun, 2022
  • 2 locations
Stenting in the Treatment of Aneurysm Trial (STAT)

The STAT trial aims at comparing coiling versus coiling plus stenting in patients with aneurysms prone to recurrence, that is large aneurysms or recurring aneurysms after previous coiling or

  • 19 Jun, 2022
  • 4 locations
Cerclage After Full Dilatation Caesarean Section (CRAFT)

trial arm; To assess treatment for short cervix in women at high risk of preterm birth following a caesarean section at full dilatation CRAFT-IMG: Imaging sub-study; To aid understanding of micro

fetal fibronectin
transvaginal ultrasound
Accepts healthy volunteers
  • 16 Feb, 2022
  • 1 location
ACT Guided Heparinization During Open Abdominal Aortic Aneurysm Repair. (ACTION-1)

Aim of the ACTION-1 study is to determine whether ACT guided heparinization decreases thrombo-embolic complications (TEC) and mortality after elective open AAA surgery, without causing more bleeding complications.

aneurysm repair
aortic aneurysm
open repair
aaa surgery
  • 02 Mar, 2022
  • 18 locations
A Study to Look at Performance of MICRUSFRAME and GALAXY Coils for the Treatment of Intracranial Aneurysms (STERLING)

A post-market registry evaluating ruptured/unruptured aneurysms treated with MICRUSFRAME and GALAXY coils

intracranial aneurysm
ruptured aneurysm
embolization procedure
  • 29 May, 2022
  • 3 locations