Found 1547 clinical trials
An MRI-Study to Characterize Cerebrospinal Fluid Geometry and Dynamics in Individuals with Rett Syndrome
Knowledge of the CSF geometry and dynamics in RTT will allow for customized intrathecal (IT) drug delivery for subjects with RTT and may help improve gene therapy distribution and exposure at the CNS target areas.Delivery of drugs to the CSF to help treat central nervous system diseases has shown promising …
- 0 views
- 15 Feb, 2022
- 1 location
A Randomized Controlled Trial of Regional versus General Anesthesia for Promoting Independence after Hip Fracture (REGAIN Trial)
A Randomized Controlled Trial of Regional versus General Anesthesia for Promoting Independence after Hip Fracture (REGAIN Trial)
- 570 views
- 23 Nov, 2020
- 1 location
Phase 1 Study To Assess the Safety and Tolerability of Human Embryonic Stem Cell-Derived Midbrain Dopamine Neuron Cell Therapy (MSK-DA01) For Advanced Parkinson's Disease
Dopamine neurons made from stem cells are injected into the brain under general anesthesia. Subjects then take medicines to partially suppress their immune system (aimed to prevent the body from
- 57 views
- 18 Apr, 2022
- 2 locations
Double-blind, placebo-controlled, parallel group, single-injection study in which subjects will be randomized to receive three doses of CNTX-4975 or placebo injected into the intermetatarsal space around a Morton's neuroma.
Double-blind, placebo-controlled, parallel group, single-injection study in which subjects will be randomized to receive three doses of CNTX-4975 or placebo injected into the intermetatarsal space around a Morton's neuroma.
- 434 views
- 08 Nov, 2020
- 1 location
Driving Pressure During General Anesthesia for Open Abdominal Surgery (DESIGNATION)
The purpose of this international multicenter, patient and outcome-assessor blinded randomized controlled trial is to determine whether the application of an individualized high PEEP strategy, aiming at avoiding an increase in the driving pressure during intraoperative ventilation, protects against the development of postoperative pulmonary complications.
- 97 views
- 11 Mar, 2022
- 19 locations
Namsos Anaesthesia Children Outcome Study (NACOS)
Behavioral disturbances are often seen in children after anesthesia both immediately after surgery (emergence delirium) and after discharge from hospital. Persisting behavioral changes may
- 2 views
- 02 Mar, 2022
- 2 locations
EEG Guidance of Anesthesia (ENGAGES-CANADA) (ENGAGES)
This study examines the potential link between deep levels of anesthesia and delirium.
- 92 views
- 24 Feb, 2022
An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study (PRIME-AIR)
and others have suggested a crucial role of anesthesia related interventions such as ventilatory strategies, and administration and reversal of neuromuscular blocking agents in reducing PPCs. These
- 75 views
- 28 Feb, 2022
- 9 locations
Ultrasound Guided Peripheral Venous Cannulation in Patient Undergoing Elective Surgery Under General Anesthesia.
This study evaluates two different techniques for peripheral venous cannulation in operating theatre. Ultrasound guided insertion of peripheral cannula in comparison with conventional approach without any ultrasound guidance.
- 0 views
- 29 Nov, 2021
- 1 location
Cardiovascular Protection Conservative Effects of Esketamine Versus µ-opioid Receptor Agonists in General Anesthesia
causes the disaster? Piles of evidence demonstrate that deep anesthesia or deep sedation is related to the high mortality of the patients (Anesthesiology. 2012; 116:1195-1203; Crit Care. 2014; 18(4):R156
- 0 views
- 02 May, 2022
- 1 location