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Found 679 clinical trials
Avatrombopag in TPO-RA Refractory Aplastic Anemia Patients Safety and Efficacy Study --Single-arm, Multicenter, Open, Phase Π Clinical Study

This study was a single-arm, multicenter, phase Π clinical study. Patients admitted to the enrollment unit center with a confirmed diagnosis of TDNSAA/VSAA/SAA, treated with IST (p/r-ATG+CSA) in combination with TPO-RA (including eltrombopta or hydtrombopta) for at least 3 months with no hematologic response at 6-month follow-up, and who were …

  • 0 views
  • 14 Sep, 2022
  • 1 location
A Randomized Trial of Sirolimus (Rapamune(R)) for Relapse Prevention in Patients With Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

Background People with severe aplastic anemia (SAA) do not make enough red and white blood cells, and/or platelets. Their body's immune system stops the bone

white blood cells
blood test
sirolimus
aplastic anemia
cyclosporine
  • 14 views
  • 19 Sep, 2022
  • 1 location
Ferric Derisomaltose (Iron Isomaltoside) Versus Iron Sucrose for Treatment of Iron Deficiency in Pregnancy

Ion deficiency anemia (IDA) is associated with poor neonatal outcomes and maternal morbidity. Iron replacement may be done with oral iron or intravenous iron, with intravenous iron being

Accepts healthy volunteers
  • 0 views
  • 01 Jul, 2022
  • 1 location
A Phase 2 Clinical Study of Pegerythropoietin Injection (RD01) for the Treatment of Anemia in Chronic Renal Failure Patients With Hemodialysis

and routes of pegerythropoietin Injection (RD01) as maintenance therapy in the treatment of anemia in chronic renal failure patients with hemodialysis

  • 3 views
  • 24 Feb, 2022
  • 1 location
T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Conditioned With a Reduced Intensity Regimen in Patients With Hematologic Malignancies and Aplastic Anemia

The main purpose of this study is to learn if a new combination of chemotherapy, in combination with low-dose radiation, will be safe for the patient, and at the same time provide the best opportunity to cure the bone marrow cancer. The combination of chemotherapy and radiation described in the …

  • 13 views
  • 21 Mar, 2022
  • 2 locations
A Phase 1 Study of SSS17 in Healthy Subjects.

This study will investigate the efficacy, safety, pharmacokinetics and pharmacodynamics of single oral administration of 5 mg, 15 mg, 20 mg and 25 mg of SSS17 compared with placebo, and evaluate the efficacy, safety, tolerance, pharmacokinetics and pharmacodynamics of multiple oral administration of 15 mg and 20 mg of SSS17 …

Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
  • 1 location
  • 0 views
  • 22 Sep, 2022
Pomalidomide for the Treatment of Bleeding in HHT (PATH-HHT)

This is a Phase II placebo-controlled double-blind study of pomalidomide in patients with hereditary hemorrhagic telangiectasia (HHT) with moderate to severe epistaxis who have anemia and/or

platelet count
iron
pomalyst
parenteral infusion
epistaxis
  • 11 views
  • 21 Jul, 2022
  • 10 locations
IUB SEAD RED (Revolutionary Endometrial Ablation Device Study

One of the AUB symptoms, heavy menstrual bleeding (HMB), can lead to iron deficiency and iron deficiency anemia and in acute and severe cases, can necessitate emergency medical care. This

sound measurement
cavity
hysteroscopy
serum pregnancy test
iron deficiency
  • 11 views
  • 30 Sep, 2021
  • 2 locations
Senicapoc and Dehydrated Stomatocytosis

Dehydrated stomatocytosis is a genetic disorder characterized by chronic hemolysis, variable anemia and erythrocyte dehydration. Causative mutations have been identified in either the Gardos

  • 0 views
  • 13 Jun, 2021
  • 1 location