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Found 9 clinical trials
Can Vitamin D Supplementation in Infants Prevent Food Allergy in the First Year of Life? The VITALITY Trial

allergy in the world, with 10% of infants having challenge-proven food allergy in Melbourne. There has been a 5-fold increase in hospital admissions for life-threatening anaphylaxis. These changes are

vitamin
anaphylaxis
atopy
atopic dermatitis
  • 25 views
  • 26 Jan, 2021
  • 1 location
Intravenous Iron for Treatment of Anaemia Before Cardiac Surgery (ITACS)

This randomised double-blind, controlled phase IV trial will compare the efficacy, safety and cost-effectiveness of preoperative IV iron with placebo in patients with anaemia before elective cardiac surgery.

iron
ferric carboxymaltose
  • 252 views
  • 23 Feb, 2022
  • 1 location
Antibiotic Prophylaxis in Patients Undergoing Elective TKA- Multi-center Trial

The Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty (TKA): Multi-Center Trial is a study that will compare the effectiveness of various perioperative strategies for antibiotic delivery as prophylaxis for periprosthetic joint infections (PJI) and surgical site infection in elective primary TKA. The investigators hypothesize that a single dose …

inflammatory arthritis
osteoarthritis
total knee replacement
cefazolin
  • 177 views
  • 10 Aug, 2022
  • 11 locations
Pilot Study on Traditional Chinese Medicine and Food Allergy (TCMFA)

> FAHF2 completely blocked peanut-induced anaphylaxis in a murine model, and currently being studied in human. Therefore, in collaboration with the Institute of Chinese Medicine, CUHK, the

Accepts healthy volunteers
  • 0 views
  • 08 Aug, 2022
  • 1 location
Tocilizumab in Schizophrenia

This study is a Phase 1 clinical trial to determine the safety, tolerability, and efficacy of Tocilizumab (Actemra) as an adjunct to antipsychotic medications in stable outpatients with schizophrenia. Tocilizumab (structural formula C6428H9976N1720O2018S42) is a recombinant humanized anti-human interleukin-6 (IL-6) receptor monoclonal antibody of the immunoglobulin G1 (IgG1) subclass. Tocilizumab …

psychiatric disorder
a 12
psychotropic drugs
schizoaffective disorder
schizophrenia
  • 290 views
  • 23 Feb, 2022
  • 1 location
Siltuximab in Schizophrenia

This study is a Phase 1 clinical trial to determine the safety, tolerability, and efficacy of Siltuximab (Sylvant) as an adjunct to antipsychotic medications in stable outpatients with schizophrenia. Siltuximab (structural formula C6450H9932N1688O2016S50) is a recombinant chimeric (human-murine) anti-human interleukin-6 (IL-6) monoclonal antibody. Siltuximab is formulated as a concentrate for …

psychotropic drugs
cancer
schizophrenia
antipsychotics
schizoaffective disorder
  • 93 views
  • 23 Feb, 2022
  • 1 location
Studies in the Pathogenesis of Systemic Capillary Leak Syndrome

Background Systemic Capillary Leak Syndrome (SCLS) is a disorder of unknown cause characterized by episodes of life-threatening drop in blood pressure and leakage of fluids into tissues. The outcome from an episode of SCLS may be mild and resolve on its own, or may be severe and result in death. …

Accepts healthy volunteers
  • 0 views
  • 10 Aug, 2022
  • 1 location
Screening Protocol for Genetic Diseases of Allergic Inflammation

disorders. To create a library of information about inherited diseases of mast cell homeostasis and activation, including piebaldism (problems with skin and hair pigmentation), anaphylaxis

inherited disease
  • 218 views
  • 29 Jul, 2022
  • 1 location
Cause of Unexplained Anaphylaxis

This study will explore the possible cause of unexplained, or idiopathic, anaphylaxis. Anaphylaxis is a rapid, life-threatening, severe reaction that occurs suddenly after contact with an

  • 38 views
  • 25 Jul, 2022
  • 1 location