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Found 42 clinical trials
CBT Group Intervention for Children With Food Allergy and Anxiety

The research will design and evaluate a CBT based intervention to support children aged 12-17 with food allergies. The research on this population has shown that they can experience high levels of anxiety in management of their allergy which can have a significant impact on quality of life. However, the …

  • 0 views
  • 07 Mar, 2021
  • 1 location
Phase I Study of MOv18 IgE a First in Class Chimeric IgE Antibody in Patients With Advanced Solid Tumours

This first in human study of the new therapeutic antibody MOv18 IgE in patients with advanced cancer seeks to demonstrate the potential for the use of this IgE antibody as an example of the use of the IgE class of antibodies for the treatment of cancer.

  • 167 views
  • 27 Jan, 2021
  • 4 locations
The Effect of Sitagliptin on Hypertension Arterial Stiffness Oxidative Stress and Inflammation

Recently a new category of antihyperglycemic therapy aiming to modulate the incretin system has emerged. These drugs induce insulin secretion without inducing hypoglycemia. The effect of the incretin modulators drugs on hypertension, arterial stiffness, inflammation and oxidative stress parameters have not been fully investigated yet.GLP-1 analogue has been suggested to …

arterial stiffness
hemoglobin a1c
sitagliptin
metformin
dipeptidyl peptidase-4 inhibitor
  • 11 views
  • 07 Nov, 2020
  • 1 location
Development of Diagnostic Pathway for Teicoplanin Allergy

Hospitals NHS Trust alone, in 2014-15. Unfortunately, anaphylaxis (a severe allergic reaction) to the drug appears to be increasing. These reactions can result in admission to intensive care, prolong

anaphylaxis
antibiotics
skin test
allergic response
  • 15 views
  • 22 Jan, 2021
  • 1 location
Diagnostic Accuracy of the MADx Multi Array Xplorer (MAX 45k) Automated Laboratory System and the MADx Allergy Explorer Version 2 (ALEX ) - IgE Multiplex Test for the Diagnosis of Pre-defined Groups of Specific High-priority Allergens

allergies (e.g. grass pollen, house dust mite or cat allergy) will be included as well as patients suffering from Hymenoptera venom allergy, which is the major cause of anaphylaxis.

  • 0 views
  • 25 Jan, 2021
  • 2 locations
Can Vitamin D Supplementation in Infants Prevent Food Allergy in the First Year of Life? The VITALITY Trial

allergy in the world, with 10% of infants having challenge-proven food allergy in Melbourne. There has been a 5-fold increase in hospital admissions for life-threatening anaphylaxis. These changes are

atopy
atopic dermatitis
vitamin
anaphylaxis
  • 18 views
  • 26 Jan, 2021
  • 1 location
COVID-19: SARS Vaccination

Background: Allergic reactions have been reported to occur after vaccination with both the Pfizer-BioNTech COVID-19 Vaccine and Moderna COVID-19 Vaccine. Allergic reactions range from mild to severe and include life- threatening anaphylactic reactions, although no deaths have been reported with either vaccine. This study is designed with two principal aims: …

  • 0 views
  • 11 Apr, 2021
  • 7 locations
Randomised Evaluation of COVID-19 Therapy

RECOVERY is a randomised trial investigating whether treatment with Lopinavir-Ritonavir, Hydroxychloroquine, Corticosteroids, Azithromycin, Colchicine, IV Immunoglobulin (children only), Convalescent plasma, Synthetic neutralizing antibodies (REGN-COV2), Tocilizumab, Aspirin, Baricitinib or Anakinra (children only) prevents death in patients with COVID-19.

ritonavir
pneumonia
covid-19
corticosteroids
azithromycin
  • 0 views
  • 11 Mar, 2021
  • 3 locations
A Trial of CONvalescent Plasma for Hospitalized Adults With Acute COVID-19 Respiratory Illness

There is currently no treatment available for COVID-19, the acute respiratory illness caused by the novel SAR-CoV-2. Convalescent plasma from patients who have recovered from COVID-19 that contains antibodies to the virus is a potential therapy. On March 25th, 2020, the FDA approved the use of convalescent plasma under the …

intubation
covid-19
  • 69 views
  • 24 Jan, 2021
  • 3 locations
Intravenous Iron for Treatment of Anaemia Before Cardiac Surgery

This randomised double-blind, controlled phase IV trial will compare the efficacy, safety and cost-effectiveness of preoperative IV iron with placebo in patients with anaemia before elective cardiac surgery.

ferric carboxymaltose
iron
  • 225 views
  • 27 Jan, 2021
  • 1 location