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Found 10 clinical trials
Iron Infusion Into a Vein Compared to Iron Tablet Taken by Mouth for Treating Iron Deficiency Anemia in Pregnancy (IVON) (IVON)

deficiency anaemia (IDA). The earliest of these, iron dextran is not commonly used because of its potential to cause anaphylactic reactions. Newer preparations have been found to be safer and their use for

Accepts healthy volunteers
  • 4 views
  • 10 Jul, 2022
  • 10 locations
Treatment With Omalizumab in Food Allergic Children (TOFAC)

often milk, egg, wheat, peanut and tree nut. Peanut and hazelnut are common triggers of severe and potentially fatal food-induced anaphylactic reactions. Currently, there is no curative treatment for

anaphylaxis
xolair
Accepts healthy volunteers
allergen
omalizumab
  • 0 views
  • 16 Oct, 2022
  • 1 location
SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors

Phase IV multi-center, US-centric, open-label, safety study enrolling participants with Hemophilia A or B with inhibitors aged 12 to 65 years, inclusive, who are either on long term prophylactic treatment (e.g., emicizumab) at risk of experiencing a breakthrough bleeding event (BE), or who are not on prophylactic treatment who may …

  • 0 views
  • 04 Oct, 2022
  • 9 locations
Uterine Serous Carcinoma and Adjuvant Combined Intraperitoneal Chemotherapy and Radiation

Uterine serous carcinoma (USC) is an uncommon, but aggressive variant of endometrial carcinoma that has poor response to standard therapy. After staging and surgery, radiation therapy and/or chemotherapy is recommended to treat patients at high risk for recurrence. In advanced stage and recurrent setting, high risk uterine cancer mirrors ovarian …

carboplatin
ovarian cancer
carcinoma
hysterectomy
metastasis
  • 0 views
  • 25 Nov, 2021
  • 1 location
Canadian Anaphylaxis Network- Predicting Recurrence After Emergency Presentation for Allergic REaction (CAN-PREPARE)

Canada, approximately every 10 minutes there is an Emergency Department (ED) visit for food allergy, and up to 80% of anaphylactic reactions in children are triggered by food. The ambiguity in how

  • 0 views
  • 06 May, 2022
  • 1 location
Acquisition and Long-term Observation of Patients With Severe Allergic Reactions

The Anaphylaxis Registry aims to assess data in a standardized form about symptoms, triggers, cofactors and therapy management from patients who experienced an anaphylactic reaction. This should improve diagnosis and long-term management of these life-threatening allergic reactions.

  • 0 views
  • 25 Mar, 2022
  • 1 location
SHARED Study (Saguenay Hospitals Anaphylaxis Rule for Early Discharge) (SHARED)

Anaphylaxis is a potentially fatal condition with a prevalence between 0.05 and 2% in the general population. This is therefore a frequent reason for emergency visits. Its diagnosis is mainly based on the NIAID / FAAN2 criteria, developed in 2006. The treatment of the condition consists of administration of intramuscular …

  • 0 views
  • 30 May, 2022
  • 1 location
A Registry for the Food Allergy Community (FPR)

The FARE Patient Registry will serve as a prospective, observational food allergy reporting system that stores detailed health and other basic information about patients' real-world experiences with food allergies, to encourage open sharing of de-identified data and participation in clinical trials. The FARE Patient Registry intends to make and support …

  • 0 views
  • 21 Mar, 2022
  • 1 location
Defining ENDOtypes in Perioperative Hypersensitivity by Extensive Cellular and Molecular PHENotyping (ENDOPHEN) (ENDOPHEN)

after the induction of anesthesia or a new product by the anesthetist. The main mechanism evoked is an immune response of immediate systemic hypersensitivity or anaphylaxis. Anaphylactic reactions are

anaphylaxis
allergen
skin test
anesthesia
  • 0 views
  • 01 May, 2022
  • 4 locations
Impact of Closely Grouped, Iterative Exposures to Suxamethonium During ECT on the Sensitization to NMBA and the Development of Protective Antibodies (SismoSens)

Acute per-anesthetic hypersensitivity reaction (HSA-PA) is a rapidly occurring systemic reaction following injection of a drug during anesthesia (mortality between 3 and 9%). The substances responsible for these reactions in France are Neuro-Muscular Blocking Agents (NMBA) in 60% of cases. The main mechanism mentioned is an immediate systemic hypersensitivity immune …

antidepressants
electroconvulsive therapy
  • 0 views
  • 23 Apr, 2022
  • 1 location