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Found 16 clinical trials
COVID-19: SARS Vaccination

severe and include life- threatening anaphylactic reactions, although no deaths have been reported with either vaccine. This study is designed with two principal aims: To estimate

  • 0 views
  • 14 May, 2021
  • 27 locations
Bioavailability of Nasal Epinephrine

A Study to Compare the Bioavailability of Epinephrine following a Single Nasal Dose of FMXIN002 Microspheres Powder with Epinephrine 0.3 mg Intramuscular Injection in Adult Subjects with Seasonal Allergic Rhinitis with and without Nasal Allergen Challenge

  • 0 views
  • 31 Jan, 2021
  • 1 location
DEpth of EPinephrine Delivery With Auto-injectors Devices

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death. Although there are several causes of fatal anaphylaxis, food allergy is one of the most common. Epinephrine is recommended as the initial treatment of choice for anaphylaxis. A delay in epinephrine administration may contribute to …

  • 19 views
  • 03 Feb, 2021
  • 1 location
Behandling af Boern Med Foedevareallergi Med Omalizumab (Xolair)

often milk, egg, wheat, peanut and tree nut. Peanut and hazelnut are common triggers of severe and potentially fatal food-induced anaphylactic reactions. Currently, there is no curative treatment for

anaphylaxis
allergen
omalizumab
xolair
  • 0 views
  • 25 Jan, 2021
  • 1 location
Use of Dexamethasone in Prevention of the Second Phase or a Biphasic Reaction of Anaphylaxis

Anaphylaxis is an acute serious allergic reaction, with multi-organ system manifestations caused by the release of chemical mediators and it is potentially fatal . Between 5% and 14% of patients may experience a recurrence of anaphylaxis 8-12 hours after the initial presentation, called biphasic (late-phase) . The mainstay of treatment …

  • 599 views
  • 25 Jan, 2021
  • 1 location
Pilot Study: Characterization of the Immune Phenotype of Patients Allergic to Wasp Venom or Penicillin

Severity of allergic reactions are highly variable from one individual to another, they can range from absent to life threatening. Allergic manifestations and specifically those of anaphylactic

anaphylaxis
allergen
penicillin
wasp venom
  • 230 views
  • 26 Jan, 2021
  • 3 locations
A Phase III Transition Study of DRL Rituximab to Reference Medicinal Products

The objective of the current study is to assess the immunogenicity and safety of transitioning subjects with RA to DRL_RI from US-rituximab/EU-rituximab to continued treatment with US-rituximab/EU-rituximab. The primary objective of this study is to assess the immunogenicity of transitioning subjects with RA to DRL_RI (biosimilar rituximab) from US-rituximab/EU-rituximab to …

methotrexate
folic acid
antirheumatics
rituxan
rituximab
  • 74 views
  • 24 Jan, 2021
  • 15 locations
SEVENFACT for Bleeding Events in Hemophilia With Inhibitors

Phase IV multi-center, US-centric, open-label, safety study enrolling participants with Hemophilia A or B with inhibitors aged 12 to 65 years, inclusive, who are either on long term prophylactic treatment (e.g., emicizumab) at risk of experiencing a breakthrough bleeding event (BE), or who are not on prophylactic treatment who may …

  • 0 views
  • 02 May, 2021
  • 7 locations
Kinetics of Nasal Cytokine Responses to Mechanical Stimulation

IgE-associated allergy is a hypersensitivity disease affecting more than 40% of the population in industrialised countries. Recently the kinetics of change of clinical and immunological parameters (e.g. nasal blockage and cytokine profiles) in response to allergen exposure have been described. Additionally through recent placebo controlled studies it has become clear …

  • 0 views
  • 13 May, 2021
  • 1 location
Quantitative Fluorescent Guided Robotic Surgery for Cancer of the Gastroesophageal Junction

The investigators also aim to use our previously described quantifying method (q-ICG), to evaluate changes in gastric perfusion, during resection of cancer in the gastroesophageal junction (GEJ) and if a change in the operative technique influences microvascular flow in the gastroesophageal (GE) anastomosis.

cancer
indocyanine green
  • 0 views
  • 25 Jan, 2021
  • 1 location