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Found 291 clinical trials
Radiofrequency Perineural Injection Idiopathic Carpal Tunnel Syndrome

Aim of the study The aim of the study is to evaluate the role of pulsed radiofrequency versus platelet rich plasma injection in treatment of idiopathic mild to moderate carpal tunnel syndrome Patients will be classified into three equal groups using randomized closed envelop method into three groups. Control Group …

nerve conduction
Accepts healthy volunteers
tingling sensation
  • 06 Oct, 2021
  • 1 location
Fractional CO2 Laser Treatment of Hypertrophic Scars

Executive Summary Hypertrophic scars are irregular, raised scars that can cause debilitating symptoms including pain, pruritus, and restricted movement in nearby joints. There are also often significant psychosocial elements with these scars that are especially significant in the vulnerable pediatric population and their parents. Current scar treatment modalities are limited. …

Accepts healthy volunteers
  • 17 Oct, 2021
  • 1 location
I-COPE Study: Opioid Use and Pain Management in Older Adults

Adults over 65 years of age are at higher risk of experiencing chronic pain and adverse events from opioids and opioid use disorder (OUD). Older adults are more likely to inadequately report their pain due to age-related health, which may lead to undertreatment of pain. In the last two decades, …

chronic pain
pain relieving
  • 17 Nov, 2021
  • 2 locations
Opioid Analgesic Reduction Study (OARS)

The goal is to provide health care professionals, including dentists, with the best possible evidence for clinical decision making when deciding upon analgesics for acute post-surgical pain

Accepts healthy volunteers
  • 22 Mar, 2022
  • 5 locations
Efficacy and Safety of VER-01 in the Treatment of Patients With Chronic Non-specific Low Back Pain

treatment of patients with chronic non-specific low back pain when drug treatment is indicated and previous optimised treatments with non-opioid analgesics have not led to sufficient pain relief or were

  • 29 Sep, 2021
  • 1 location
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients (CODEX)

Anesthesia is a drug induced, reversible, comatose state that facilitates surgery and it is widely assumed that cognition returns to baseline after anesthetics have been eliminated. However, many patients have persistent memory impairment for weeks to months after surgery. Cardiac surgery appears to carry the highest risk of postoperative cognitive …

cognitive deficits
cognitive disorder
postoperative cognitive dysfunction
  • 28 Feb, 2022
  • 1 location
Effect of Combinations of Paracetamol, Ibuprofen, and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty (RECIPE)

paracetamol and ibuprofen is superior to each single drug when assessing pain after hip replacement. Further improvement is needed, investigating additional non-opioid analgesics to this combination

hip arthroplasty
  • 09 Mar, 2022
  • 5 locations
Effect of Nalmefene on the Quality of Resuscitation in Patients Under General Anesthesia

the perioperative period are opioid analgesics, sedatives and muscle relaxants. Studies have shown that intravenous opioids are more difficult to control than neuromuscular relaxants. Opioids can

  • 21 Oct, 2022
  • 3 locations
PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients (PANDORA)

Our objective is to find an effective prophylactic intervention by evaluating IV acetaminophen's impact in reducing the frequency of postoperative delirium, one of the most common and detrimental complications of cardiac surgery in older adults.

bypass graft
postoperative delirium
heart surgery
coronary artery bypass graft
  • 03 Jul, 2022
  • 6 locations
Does Higher OT Temperature and IV Ondansetron Reduce Incidence of PSS in Parturients?

This study will look at the incidence of post-spinal shivering (PSS) among the obstetrics population and will investigate whether higher operation theater (OT) temperature range or/and IV Ondansetron are able to reduce the incidence of PSS. This is a double-blind, randomized, factorial study, patients will be grouped into 4 groups …

Accepts healthy volunteers
  • 21 Oct, 2021
  • 1 location