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Found 300 clinical trials
Recruitment Assessment in Patients With Acute Respiratory Distress Syndrome and Covid-19

Respiratory failure associated with Covid-19 can be expressed as acute respiratory distress syndrome (ARDS), which is an acute inflammatory lung injury,which generally requires the use of invasive mechanical ventilation (MV). There are inconclusive results regarding the potential lung recruitment in ARDS. Recently, a new index based on lung compliance has …

mechanical ventilation
respiratory failure
acute respiratory distress
positive end expiratory pressure
assisted ventilation
  • 12 Apr, 2022
Gene Polymorphisms and Morphine Analgesic Consumption

Variation of morphine requirements are seen considerably. Studies showed that pharmacogenetics (PGx) could possibly be used to tailor pain medication according to an individual's genetic background. While prior studies demonstrated the association of genetic polymorphism with opioid requirements in various types of surgeries in Asian and European populations, there are …

  • 16 Aug, 2021
  • 1 location
Analgesic Consumption in Chronic Marijuana Users Following Orthopedic Trauma Surgery

Marijuana use has increased since its legalization in Canada and many believe that it may help patients that are experiencing chronic pain. The investigators want to assess if patients who have used marijuana chronically will need more medication to control their pain after they have undergone orthopedic trauma surgery (ex. …

  • 08 Jun, 2022
  • 1 location
Analgesic Effectiveness of the Serratus-intercostal Plane Block Versus Quadratus Lumborum Block in Nephrectomy: Randomized Study

Performing the nephrectomy by laparoscopy has decrease the incidence of postoperative pain, but there are still some patients who describe a severe pain after this surgery. Regional techniques allow a better recovery quality and adequate- managed pain control.

postoperative pain
  • 15 Oct, 2022
  • 1 location
Measuring Analgesic Interventions

It is generally recognized that pain assessment and management especially in newborns, children and other nonverbal populations is an unmet need. According to the American Medical Association, "the pediatric population is at risk of inadequate pain management, with age-related factors affecting pain management in children. Children are often given minimal …

pain assessment
pain relieving
  • 24 Feb, 2022
  • 1 location
Study of Postoperative Respiratory Complications in Children With Obstructive Sleep Apnea (PORC) (PORC)

Adenotonsillectomy is the first line surgical treatment for children with Obstructive Sleep apnea Syndrome (OSAS). Postoperative respiratory complications (PORC) may occur and are often related to co-morbidities. Despite guidelines from different scientific groups, there is no consensus on the monitoring requirements and management of PORC in these children.

  • 04 Oct, 2022
  • 1 location
An Open Internet-based Survey and Natural Language Processing Project Analysing Written Monologues by Headache Patients

Headache disorders are among the most prevalent medical conditions worldwide. The diagnosis of headache disorders is based on medical history taking. Digital solutions such as natural language processing (NLP) may be of aid to understand the linguistic aspects of headache attack and headache related disability descriptions by patients. Participants will …

headache disorder
  • 16 Dec, 2021
  • 1 location
Dysbiosis Impact on Lung Disease in HIV (DimPL)

Despite the high burden of respiratory symptoms in the HIV+ population, causes of chronic obstructive pulmonary disease (COPD) in individuals with HIV are poorly understood. Microbial communities present in the lungs or gut could play an important role in COPD via their ability to stimulate inflammation and oxidative stress and …

respiratory symptom
HIV Vaccine
hiv-1 infection
pulmonary function test
  • 17 Feb, 2022
  • 1 location
CGRP Inhibition, Autonomic Function, and Migraine (CGRP-1)

The purpose of this clinical study is to better understand the function of the autonomic nervous system in patients with migraine. We aim to understand whether the autonomic functions change depending on the migraine status (i.e. whether they are between or during attacks) and whether the CGRP monoclonal antibody (mAb) …

Accepts healthy volunteers
  • 24 Apr, 2022
  • 1 location
NUMITOR Study: Nummular Headache Iberian Study on the Treatments and Outcomes in Real-World Setting (NUMITOR)

The NUMITOR study is an analytical observational study with an multicenter ambisective (retrospective and prospective) cohort design.

  • 04 Oct, 2022
  • 1 location