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Found 696 clinical trials
Wound Healing Endpoint and Recurrence

This prospective pilot study is to enroll patients with clinically-defined infected wounds. Patients enrolled in the study will be followed for 16 weeks for wound closure (Phase A), and will then begin Phase B. 265 clinically diagnosed infected burn or chronic wound patients will be recruited for this study in …

epiceram
vaseline
wound treatment
wound infection
decubitus ulcer
  • 156 views
  • 11 Jul, 2022
  • 1 location
The Role of Bacterial Toxins in Human Skin Disease

Atopic dermatitis and psoriasis are two skin diseases often associated with bacterial infections and inflammation. Studies indicate that skin cells from these patients may have some changes that make these patients more susceptible to bacterial infections. Inflammatory environment may have an effect on the function of skin cells. The purpose …

psoriasis
bacterial infection
elidel
antibiotics
topical corticosteroid
  • 269 views
  • 23 Feb, 2022
  • 1 location
Myocardial Injury Following Non-cardiac Surgery (EMINENT)

It is estimated that > 200 million patients in the world undergo surgery each year of which approximately 10 million will suffer from a myocardial injury in the perioperative period. Mortality is high in patients with myocardial injury since it often goes undiagnosed and management is unclear. In contrast to …

artery disease
heart surgery
troponin
infarct
myocardial infarction
  • 1 views
  • 03 Jun, 2022
  • 1 location
Dysbiosis Impact on Lung Disease in HIV (DimPL)

Despite the high burden of respiratory symptoms in the HIV+ population, causes of chronic obstructive pulmonary disease (COPD) in individuals with HIV are poorly understood. Microbial communities present in the lungs or gut could play an important role in COPD via their ability to stimulate inflammation and oxidative stress and …

pulmonary function test
drug use
respiratory symptom
hiv-1 infection
HIV Vaccine
  • 0 views
  • 17 Feb, 2022
  • 1 location
Exploring Immune Cell Signatures in Autoimmunity and Dry Eye Syndrome

Ocular surface disease, especially dry eye and scleritis, commonly affects patients with autoimmune diseases. Ocular surface immune cells are increased in autoimmune disease; however the full subset of immune cells activated is unknown. Recent experimental studies show that dendritic cells and T cells in the cornea are critically associated with …

systemic lupus erythematosus
erythema
contact lens prescription
tearing
lupus
  • 120 views
  • 06 Apr, 2022
  • 1 location
Liquid Biopsy for ctDNA in Peritoneal Lavage and Blood in Pancreatic Cancer (LIPAC)

Pancreatic cancer (PC) is a deadly disease and surgical resection of the tumor is the only hope of cure. Approximately 20-25% of the PC patients are candidates for intended curative resection, but despite microscopically radical resection the majority of patients will have recurrent disease within 2 years. This indicates that …

KRAS
cancer chemotherapy
tumor cells
pdac
pancreatic resection
  • 0 views
  • 16 Jun, 2022
  • 1 location