Found 163 clinical trials
Methodology Study of Novel Electrophysiological, Physical, and Imaging Outcome Measures to Assess the Progression of Amyotrophic Lateral Sclerosis
Methodology Study of Novel Electrophysiological, Physical, and Imaging Outcome Measures to Assess the Progression of Amyotrophic Lateral Sclerosis
- 209 views
- 23 Nov, 2020
- 1 location
New Approaches to Dementia Heterogeneity.
This study is looking for adults who have mild cognitive impairment, Alzheimer’s, or other forms of dementia. The study is also looking for people with normal cognition, as a comparison. The study is interested in the ways that brain function changes over time with the goal of improving the ability to diagnose …
- 160 views
- 25 May, 2021
- 1 location
A Phase 3 Randomized, Placebo-Controlled Trial With a Longitudinal Natural History Run-In and Open-Label Extension to Evaluate BIIB067 Initiated in Clinically Presymptomatic Adults With a Confirmed Superoxide Dismutase 1 Mutation (ATLAS)
initiated prior to versus at the time of emergence of clinically manifest amyotrophic lateral sclerosis (ALS).
- 8 views
- 17 Sep, 2022
- 27 locations
Adenosine 2A Receptor Antagonism and AIH in ALS
intermittent hypoxia, or AIH), on breathing. This project will study breathing in people with amyotrophic lateral sclerosis (ALS) and unaffected, age-matched adults. Istradefylline is prescribed to increase
- 0 views
- 24 Jul, 2022
- 1 location
Efficacy and Safety Extension Study of Oral Edaravone Administered in Subjects With ALS
To evaluate and compare the efficacy of two dosing regimens of oral edaravone in subjects with amyotrophic lateral sclerosis (ALS), based on the time from the randomization date in Study MT-1186
- 0 views
- 05 May, 2022
- 9 locations
Social Cognition in Patients With Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis, also known as Charcot disease, is a neurodegenerative disease evidenced by gradual paralysis of the muscles involved in voluntary motor function. The clinical
- 0 views
- 27 Jan, 2021
- 1 location
Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease (3TLA)
A two-arm, individual participant randomised controlled, assessor-blinded trial in 7 MND care centres across Australia will be undertaken.
- 0 views
- 12 Jul, 2022
- 1 location
A Study of Monepantel in Individuals With Motor Neurone Disease
Amyotrophic lateral sclerosis/ Motor Neurone Disease (ALS/MND) is a rare and invariably fatal neurological disease. ALS/MND has a terribly high burden on patients, family and carers, and carries
- 0 views
- 15 Jul, 2022
- 2 locations
![Clinical Applications of (S)-[18F]FBFP PET/CT in Healthy Volunteers and Patients With Central Nervous System Diseases](/media/imagery/298168.svg)
Clinical Applications of (S)-[18F]FBFP PET/CT in Healthy Volunteers and Patients With Central Nervous System Diseases
This is an open-label whole-body PET/CT (positron emission tomography/computed tomography) study for investigation of radiation dosimetry, plasma pharmacokinetics, biodistribution, safety and diagnostic performance of (S)-[18F]FBFP in healthy volunteers and patients with central nervous system diseases. A single dose of nearly 370 MBq (S)-[18F]FBFP will be intravenously injected into healthy volunteers …
- 0 views
- 30 Apr, 2022
- 1 location
Evaluation of Vision-Guided Shared Control for Assistive Robotics Manipulators (ARM Control)
The purpose of this study is to evaluate a new control (i.e., the vision-guided shared control) for a wheelchair-mounted assistive robotic manipulator among powered wheelchair users. This study will consist of a questionnaire about general demographics, health information, and previous experience with assistive technology. Several tests will also be administered …
- 0 views
- 14 Jun, 2022
- 1 location