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Found 257 clinical trials
Carpal Tunnel Syndrome and Amyloidosis (AMICAR)

amyloid.

amyloid
amyloid deposition
carpal tunnel release
  • 13 views
  • 25 Feb, 2022
  • 1 location
A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis

treatment and Arm B: daratumumab + deferred VCd) in newly diagnosed systemic amyloid light chain (AL) amyloidosis with cardiac involvement and to identify potential mitigation strategies for cardiac

dexamethasone
amyloid deposition
daratumumab
cyclophosphamide
  • 0 views
  • 06 Jun, 2022
  • 1 location
Amyloidosis TTR Flow Reserve Evaluation (AMYTRE)

Anginal symptoms and signs of ischemia have been reported in some patients with cardiac amyloidosis (TTR) without obstructive epicardial coronary artery disease (CAD). It was found that

  • 0 views
  • 27 Jun, 2022
  • 1 location
Molecular Imaging of Primary Amyloid Cardiomyopathy (MICA)

Cardiac amyloidosis is a major cause of early treatment-related death and poor overall survival in individuals with systemic light chain amyloidosis. This project will develop a novel approach

multiple myeloma
heart failure
cardiac amyloidosis
immunofixation
nt-probnp
  • 28 views
  • 23 Feb, 2022
  • 1 location
Brain iron, amyloid, and Alzheimer's disease

The goal of this study is to determine how levels of iron in the brain can affect proteins associated with Alzheimer’s disease, including amyloid.

amyloid
  • 0 views
  • 03 Mar, 2022
  • 1 location
Cerebral Amyloid Imaging Using Florbetapir (AV-45) (IDEA3)

This study is aimed at examining the interest of amyloid radiotracer Florbetapir (18F-AV-45) for the etiological diagnosis of poststroke cognitive impairment and dementia

cognitive impairment
amyloid
18f-av-45
stroke
cognitive assessment
  • 3 views
  • 24 Jan, 2022
  • 1 location
Ixazomib Maintenance Study in Patients With AL Amyloidosis

prevent or delay relapse of AL Amyloidosis.

neutrophil count
platelet count
stem cell transplantation
congo red
measurable disease
  • 140 views
  • 26 Mar, 2022
  • 8 locations
Daratumumab and Pomalidomide in Previously Treated Patients With AL Amyloidosis

This study aims at establishing a new powerful combination of daratumumab and pomalidomide as rescue treatment for patients with R/R AL amyloidosis.

alkylating agent
dexamethasone
daratumumab
bone marrow procedure
  • 0 views
  • 30 Jun, 2021
  • 3 locations
Propylene Glycol-Free Melphalan Hydrochloride (Evomela) in AL Amyloidosis Patients

This is a single arm, open label study designed to evaluate the safety and efficacy of propylene glycol-free melphalan hydrochloride in patients with AL amyloidosis. Treatment will be comprised

  • 2 views
  • 24 Mar, 2022
  • 1 location
Amyloid Plaque Deposition in Chemotherapy-Induced Cognitive Impairment

increased amyloid plaque burden as a potential contributing factor to the cognitive deficits and complaints seen in patients experiencing CICI. The novel feature of this project is in the combined use of

adjuvant chemotherapy
immunostimulant
  • 1 views
  • 25 Mar, 2022
  • 1 location