Found 247 clinical trials
Hypertension Intracranial Pulsatility and Brain Amyloid-beta Accumulation in Older Adults (HIPAC Trial)
The aim of this study is to determine if lowering blood pressure using FDA approved medication (antihypertensive drugs) alters brain pulsatility and reduces brain amyloid beta protein
- 0 views
- 16 Jun, 2021
- 1 location
![[Remote] Cognitive Impairment Registry](/media/imagery/255756.svg)
[Remote] Cognitive Impairment Registry
The purpose of this study is to develop a recruitment registry of potential drug study participants who may have amyloid, a specific biomarker for Alzheimer's disease, using a phone assessment
- 0 views
- 23 Nov, 2020
- 1 location
A Washington University sleep research study seeks healthy participants.
A Washington University sleep research study seeks healthy participants.
- 1876 views
- 25 Mar, 2021
- 1 location
Proteins and Brain Networks in Atypical Alzheimer's Disease
Participants will take part in 2-4 study visits including detailed history and neurological exam, pen-&-paper cognitive testing, and functional MRI and PET scans designed to help us understand how different forms of Alzheimer's disease affect brain circuits over time.
- 37 views
- 31 Aug, 2020
- 1 location
A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease
A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease
- 82 views
- 25 Mar, 2021
- 1 location
A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease
A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease
- 142 views
- 08 Dec, 2020
- 1 location
First-in-Human Study of NI006 in Patients With Amyloid Transthyretin Cardiomyopathy
extension phase in subjects with Amyloid Transthyretin Cardiomyopathy (ATTR-CM).
- 0 views
- 01 Aug, 2021
- 7 locations
A Trial of Doxycycline vs. Standard Supportive Therapy in Newly-diagnosed Cardiac AL Amyloidosis Patients Undergoing Bortezomib-based Therapy
antibodies, the light chains (LC) that form amyloid deposits. Almost every organ, with the exception of the brain, can be affected by AL amyloidosis. The heart is involved in three fourths of patients and is
- 26 views
- 28 Jan, 2021
- 8 locations
BCG and Plasma Amyloid in Non-Demented Adults
a plasma test for amyloid, a biomarker for cerebral amyloid.
- 3 views
- 29 Apr, 2021
- 1 location
Long-term Monitoring of Patients With Cardiac Amyloidosis With Implantable Event Monitors
Researchers are gathering information to see if using an FDA approved implantable device can help with monitoring of your heart arrhythmias.
- 0 views
- 26 Jan, 2021