Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 258 clinical trials
Diagnosis of Alzheimer's Disease Using Event Related Potentials

This study evaluates the use of an EEG device using Event Related Potentials to help diagnose Alzheimer's Disease in the outpatient clinical setting.

memory loss
memory impairment
alzheimer's disease
  • 5 views
  • 23 Feb, 2022
  • 1 location
Predicting Cognition After DBS for Parkinson's Disease

The aim of the study is to improve estimation of cognitive outcome after STN-DBS in PD in order to avoid risk factors by optimizing peri- and intraoperative management personalize therapeutic strategies for optimal long-term benefit The investigators will test possible predictors (clinical, neuropsychological, neuroimaging, electrophysiological and molecular) for the risk …

brain stimulation
cognitive impairment
  • 0 views
  • 09 Feb, 2022
  • 1 location
Biomarkers in Polyradiculoneuropathies (BIP)

The nodes of Ranvier contain ion channels that enable the rapid propagation of the nerve impulse. Cell adhesion molecules and glycolipids play an important role in the formation of the nodes of Ranvier. Antibodies against glycolipids are detected in half of patients with Guillain-Barr syndrome, an acute inflammatory neuropathy affecting …

adhesion
inflammatory neuropathy
neuromuscular diseases
polyradiculoneuropathy
cell adhesion molecules
  • 59 views
  • 24 Feb, 2022
  • 1 location
Atlas of Retinal Imaging in Alzheimer's Study (ARIAS)

The Atlas of Retinal Imaging in Alzheimer's (ARIAS) study is a 5-year study examining the natural history of retinal imaging biomarkers associated with disease risk, disease burden, and disease progression in Alzheimer's disease (AD). The objective of this project is to create a 'gold standard' reference database of structural anatomic …

cognitive assessment
Accepts healthy volunteers
depression
cognitive impairment
alzheimer's disease
  • 0 views
  • 25 Jan, 2022
  • 3 locations
Tau PET Imaging in the NACC Study Cohort (TPI)

The purpose of this study is to measure the amount of a protein in the brain known as tau using an imaging procedure called Positron Emission Tomography (PET/CT). 18F-AV-1451 is a specialized radioactive PET imaging agent that is able to detect the presence of tau in the brain. In this …

amyloid
mental deterioration
Accepts healthy volunteers
amyloidosis
alzheimer's disease
  • 0 views
  • 29 May, 2022
  • 1 location
Longitudinal Study of Mild Cognitive Impairment in Parkinson's Disease (PD-MCI)

Parkinson's disease (PD) is known for its motor symptoms and affects more than 100,000 Canadians. However, PD patients also show cognitive deficits and neuropsychiatric problems that significantly impair their quality of life. The occurrence of dementia in PD is much higher than in the general population. The proposed study will …

cognitive disorder
Accepts healthy volunteers
demented
cognitive impairment
dementia
  • 125 views
  • 23 Feb, 2022
  • 1 location
CNS Tau Kinetics in Healthy Aging and Alzheimer's Disease

Alzheimer's disease (AD) is the most common cause of dementia and currently has no disease modifying treatments or simple accurate diagnostic tests. The goal of this project is to study how tau (a protein thought to cause AD) is made, transported and cleared in the human body. Better understanding of …

neurological disorder
l-leucine
Accepts healthy volunteers
neurological disorders
alzheimer's disease
  • 92 views
  • 03 May, 2022
  • 1 location
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic Inflammatory and Takotsubo Cardiomyopathy (MEMORY)

Manganese is a calcium analogue which actively enters viable cells with intact calcium-handling mechanisms and its uptake is evident by an increase in MRI-detectable T1 relaxivity of tissues. Mangafodipir is a novel manganese-based magnetic resonance imaging (MRI) contrast medium with unique biophysical properties that are ideal for application to cardiac …

angiography
Accepts healthy volunteers
MRI
electrocardiogram
heart failure
  • 47 views
  • 18 Oct, 2021
  • 1 location