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Found 247 clinical trials
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Hypertension Intracranial Pulsatility and Brain Amyloid-beta Accumulation in Older Adults (HIPAC Trial)

The aim of this study is to determine if lowering blood pressure using FDA approved medication (antihypertensive drugs) alters brain pulsatility and reduces brain amyloid beta protein

calcium
beta amyloid protein
hypertension
angiotensin ii
mental state examination
  • 0 views
  • 16 Jun, 2021
  • 1 location
featured
[Remote] Cognitive Impairment Registry

The purpose of this study is to develop a recruitment registry of potential drug study participants who may have amyloid, a specific biomarker for Alzheimer's disease, using a phone assessment

  • 0 views
  • 23 Nov, 2020
  • 1 location
featured
A Washington University sleep research study seeks healthy participants.

A Washington University sleep research study seeks healthy participants.

  • 1876 views
  • 25 Mar, 2021
  • 1 location
featured
Proteins and Brain Networks in Atypical Alzheimer's Disease

Participants will take part in 2-4 study visits including detailed history and neurological exam, pen-&-paper cognitive testing, and functional MRI and PET scans designed to help us understand how different forms of Alzheimer's disease affect brain circuits over time.

  • 37 views
  • 31 Aug, 2020
  • 1 location
featured
A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

  • 82 views
  • 25 Mar, 2021
  • 1 location
featured
A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease

A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease

  • 142 views
  • 08 Dec, 2020
  • 1 location
First-in-Human Study of NI006 in Patients With Amyloid Transthyretin Cardiomyopathy

extension phase in subjects with Amyloid Transthyretin Cardiomyopathy (ATTR-CM).

  • 0 views
  • 01 Aug, 2021
  • 7 locations
A Trial of Doxycycline vs. Standard Supportive Therapy in Newly-diagnosed Cardiac AL Amyloidosis Patients Undergoing Bortezomib-based Therapy

antibodies, the light chains (LC) that form amyloid deposits. Almost every organ, with the exception of the brain, can be affected by AL amyloidosis. The heart is involved in three fourths of patients and is

  • 26 views
  • 28 Jan, 2021
  • 8 locations
BCG and Plasma Amyloid in Non-Demented Adults

a plasma test for amyloid, a biomarker for cerebral amyloid.

  • 3 views
  • 29 Apr, 2021
  • 1 location
Long-term Monitoring of Patients With Cardiac Amyloidosis With Implantable Event Monitors

Researchers are gathering information to see if using an FDA approved implantable device can help with monitoring of your heart arrhythmias.

  • 0 views
  • 26 Jan, 2021